Murcko scaffold

N-(6,7-Dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)thiophene-2-carboxamide scaffold

16 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 21
Chemicals: 16
With full pages: 3

Scaffold SMILES

O=C(Nc1nc2cc3c(cc2s1)OCCO3)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-(6,7-Dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)thiophene-2-carboxamide page

Murcko scaffold O=C(Nc1nc2cc3c(cc2s1)OCCO3)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-(3-Methyl-6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-ylidene)thiophene-2-carboxamide

CAS 1321874-16-1C₁₅H₁₂N₂O₃S₂

5-Chloro-N-(6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)thiophene-2-carboxamide

CAS 892857-30-6C₁₄H₉ClN₂O₃S₂

N-(6,7-Dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)thiophene-2-carboxamide

CAS 892855-27-5C₁₄H₁₀N₂O₃S₂

N-(6,7-Dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)-5-nitrothiophene-2-carboxamide

CAS 892856-62-1C₁₄H₉N₃O₅S₂

5-Bromo-N-(6,7-dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)thiophene-2-carboxamide

CAS 892857-23-7C₁₄H₉BrN₂O₃S₂

5-Bromo-N-(2-(diethylamino)ethyl)-N-(6,7-dihydro-[1,4]dioxino[2',3':4,5]benzo[1,2-d]thiazol-2-yl)thiophene-2-carboxamide hydrochloride

CAS 1052534-09-4C₂₀H₂₃BrClN₃O₃S₂

5-Bromo-N-(6,7-dihydro-[1,4]dioxino[2',3':4,5]benzo[1,2-d]thiazol-2-yl)-N-(2-(dimethylamino)ethyl)thiophene-2-carboxamide hydrochloride

CAS 1052531-78-8C₁₈H₁₉BrClN₃O₃S₂

$5-Chloro-N-[2-(diethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride chemical structure, C20H23Cl2N3O3S2, CAS 1216760-41-6$

5-Chloro-N-[2-(diethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride

CAS 1216760-41-6C₂₀H₂₃Cl₂N₃O₃S₂

$5-Chloro-N-[2-(dimethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride chemical structure, C18H19Cl2N3O3S2, CAS 1216622-99-9$

5-Chloro-N-[2-(dimethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride

CAS 1216622-99-9C₁₈H₁₉Cl₂N₃O₃S₂

5-Chloro-N-(6,7-dihydro-[1,4]dioxino[2',3':4,5]benzo[1,2-d]thiazol-2-yl)-N-(3-(dimethylamino)propyl)thiophene-2-carboxamide hydrochloride

CAS 1328685-27-3C₁₉H₂₁Cl₂N₃O₃S₂

$N-[3-(Dimethylamino)propyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}-5-nitrothiophene-2-carboxamide hydrochloride chemical structure, C19H21ClN4O5S2, CAS 1135137-58-4$

N-[3-(Dimethylamino)propyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}-5-nitrothiophene-2-carboxamide hydrochloride

CAS 1135137-58-4C₁₉H₂₁ClN₄O₅S₂

$5-Bromo-N-[3-(dimethylamino)propyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride chemical structure, C19H21BrClN3O3S2, CAS 1135195-41-3$

5-Bromo-N-[3-(dimethylamino)propyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride

CAS 1135195-41-3C₁₉H₂₁BrClN₃O₃S₂

$N-[2-(Dimethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride chemical structure, C18H20ClN3O3S2, CAS 1135211-55-0$

N-[2-(Dimethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride

CAS 1135211-55-0C₁₈H₂₀ClN₃O₃S₂

$N-[2-(Dimethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}-5-nitrothiophene-2-carboxamide hydrochloride chemical structure, C18H19ClN4O5S2, CAS 1321715-09-6$

N-[2-(Dimethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}-5-nitrothiophene-2-carboxamide hydrochloride

CAS 1321715-09-6C₁₈H₁₉ClN₄O₅S₂

$N-[2-(Diethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride chemical structure, C20H24ClN3O3S2, CAS 1322238-74-3$

N-[2-(Diethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}thiophene-2-carboxamide hydrochloride

CAS 1322238-74-3C₂₀H₂₄ClN₃O₃S₂

$N-[2-(Diethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}-5-nitrothiophene-2-carboxamide hydrochloride chemical structure, C20H23ClN4O5S2, CAS 1321730-65-7$

N-[2-(Diethylamino)ethyl]-N-{10,13-dioxa-4-thia-6-azatricyclo[7.4.0.0^{3,7}]trideca-1,3(7),5,8-tetraen-5-yl}-5-nitrothiophene-2-carboxamide hydrochloride

CAS 1321730-65-7C₂₀H₂₃ClN₄O₅S₂

N-(6,7-Dihydro-[1,4]dioxino[2,3-f][1,3]benzothiazol-2-yl)thiophene-2-carboxamide scaffold

Chemicals with this scaffold

Related scaffolds