Murcko scaffold
Ring system with 3 rings and 26 atoms
24 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 26
- Chemicals
- 24
- With full pages
- 2
Scaffold SMILES
O=C(NC(=S)Nc1cccc(NC(=O)c2ccco2)c1)c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 24 of 24 chemicals
![N-[3-({[(3,4-Dimethylphenyl)carbonyl]carbamothioyl}amino)phenyl]furan-2-carboxamide chemical structure, C21H19N3O3S, CAS 335213-19-9](/s/AIISDSOWMARONQ-UHFFFAOYSA-N.svg)
N-[3-({[(3,4-Dimethylphenyl)carbonyl]carbamothioyl}amino)phenyl]furan-2-carboxamide
CAS 335213-19-9C21H19N3O3S
![N-[3-({[(3,4-Dimethoxyphenyl)carbonyl]carbamothioyl}amino)phenyl]furan-2-carboxamide chemical structure, C21H19N3O5S, CAS 335214-03-4](/s/FWUKBDLGECZFBW-UHFFFAOYSA-N.svg)
N-[3-({[(3,4-Dimethoxyphenyl)carbonyl]carbamothioyl}amino)phenyl]furan-2-carboxamide
CAS 335214-03-4C21H19N3O5S
![N-[3-[(2-Methoxy-3-methylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C21H19N3O4S, CAS 836664-67-6](/s/AFDSTMZYAQFGKH-UHFFFAOYSA-N.svg)
N-[3-[(2-Methoxy-3-methylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 836664-67-6C21H19N3O4S
![N-[3-[(2,4-Dimethylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C21H19N3O3S, CAS 700849-69-0](/s/WGHZGZDZJWNOSQ-UHFFFAOYSA-N.svg)
N-[3-[(2,4-Dimethylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 700849-69-0C21H19N3O3S
![N-[3-[(3-Iodobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14IN3O3S, CAS 425679-07-8](/s/YHIRJRWMNKUQPA-UHFFFAOYSA-N.svg)
N-[3-[(3-Iodobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 425679-07-8C19H14IN3O3S
![N-[3-[(2-Bromobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14BrN3O3S, CAS 378757-00-7](/s/QENMSOHVEKWSLH-UHFFFAOYSA-N.svg)
N-[3-[(2-Bromobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 378757-00-7C19H14BrN3O3S
![N-[3-[(5-Chloro-2-methoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C20H16ClN3O4S, CAS 426232-37-3](/s/BMRMTPZNXCCPHV-UHFFFAOYSA-N.svg)
N-[3-[(5-Chloro-2-methoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 426232-37-3C20H16ClN3O4S
![N-[3-[(4-Ethoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C21H19N3O4S, CAS 428476-37-3](/s/JDDOEFBYWBZTPV-UHFFFAOYSA-N.svg)
N-[3-[(4-Ethoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428476-37-3C21H19N3O4S
![N-[3-[(4-Propan-2-ylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C22H21N3O3S, CAS 428832-46-6](/s/YGHKOXHFUBAHLM-UHFFFAOYSA-N.svg)
N-[3-[(4-Propan-2-ylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428832-46-6C22H21N3O3S
![N-[3-[(4-Bromobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14BrN3O3S, CAS 674362-60-8](/s/YXCQEYHBIBUUSO-UHFFFAOYSA-N.svg)
N-[3-[(4-Bromobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 674362-60-8C19H14BrN3O3S
![N-[3-[(3-Methylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C20H17N3O3S, CAS 381684-76-0](/s/UMJFKHAWRMEWEZ-UHFFFAOYSA-N.svg)
N-[3-[(3-Methylbenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 381684-76-0C20H17N3O3S
![N-[3-[(2-Iodobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14IN3O3S, CAS 428447-25-0](/s/HONUSLQBAQGMGA-UHFFFAOYSA-N.svg)
N-[3-[(2-Iodobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428447-25-0C19H14IN3O3S
![N-[3-[(2-Fluorobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14FN3O3S, CAS 378778-79-1](/s/GXHQJWWRHJLSKD-UHFFFAOYSA-N.svg)
N-[3-[(2-Fluorobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 378778-79-1C19H14FN3O3S
![N-[3-[(4-Methoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C20H16N4O6S, CAS 425682-64-0](/s/XZKQDICQTXNLOL-UHFFFAOYSA-N.svg)
N-[3-[(4-Methoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 425682-64-0C20H16N4O6S
![N-[3-[(3,5-Dichloro-2-methoxybenzoyl)carbamothioylamino]-4-methoxyphenyl]furan-2-carboxamide chemical structure, C21H17Cl2N3O5S, CAS 708287-89-2](/s/YJKDYGUVHANFIU-UHFFFAOYSA-N.svg)
N-[3-[(3,5-Dichloro-2-methoxybenzoyl)carbamothioylamino]-4-methoxyphenyl]furan-2-carboxamide
CAS 708287-89-2C21H17Cl2N3O5S
![N-[4-Methoxy-3-[(2-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C20H16N4O6S, CAS 831253-12-4](/s/XUGPIUBKWWYHDL-UHFFFAOYSA-N.svg)
N-[4-Methoxy-3-[(2-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 831253-12-4C20H16N4O6S
![N-[3-[(4-Chlorobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14ClN3O3S, CAS 347328-31-8](/s/DMTSOMRHAKLUTG-UHFFFAOYSA-N.svg)
N-[3-[(4-Chlorobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 347328-31-8C19H14ClN3O3S
![N-[3-[(3-Chlorobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14ClN3O3S, CAS 347329-09-3](/s/GZVOGRJJHJSEOT-UHFFFAOYSA-N.svg)
N-[3-[(3-Chlorobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 347329-09-3C19H14ClN3O3S
![N-[3-[(3-Propoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C22H21N3O4S, CAS 428460-26-8](/s/LDCYKYRSSXCSQR-UHFFFAOYSA-N.svg)
N-[3-[(3-Propoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428460-26-8C22H21N3O4S
![N-[3-[(4-Ethoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C21H18N4O6S, CAS 428495-10-7](/s/PWKPCYIWPJJYRK-UHFFFAOYSA-N.svg)
N-[3-[(4-Ethoxy-3-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428495-10-7C21H18N4O6S
![N-[3-[(3-Nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C19H14N4O5S, CAS 428501-68-2](/s/KXHRYBFFNVSSCN-UHFFFAOYSA-N.svg)
N-[3-[(3-Nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428501-68-2C19H14N4O5S
![N-[3-[(4-Methyl-3-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C20H16N4O5S, CAS 428477-37-6](/s/FYUCWBHINOPIRV-UHFFFAOYSA-N.svg)
N-[3-[(4-Methyl-3-nitrobenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 428477-37-6C20H16N4O5S
![N-[3-[(3,4,5-Triethoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide chemical structure, C25H27N3O6S, CAS 355432-35-8](/s/RLVXCAZZZSADQJ-UHFFFAOYSA-N.svg)
N-[3-[(3,4,5-Triethoxybenzoyl)carbamothioylamino]phenyl]furan-2-carboxamide
CAS 355432-35-8C25H27N3O6S
![N-[3-({[2-(2-Ethoxyethoxy)benzoyl]carbamothioyl}amino)phenyl]furan-2-carboxamide chemical structure, C23H23N3O5S, CAS 1030429-31-2](/s/AUABMWFABGQPQI-UHFFFAOYSA-N.svg)
N-[3-({[2-(2-Ethoxyethoxy)benzoyl]carbamothioyl}amino)phenyl]furan-2-carboxamide
CAS 1030429-31-2C23H23N3O5S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(COc1ccccc1)Nc1cccc(NC(=O)c2ccco2)c19 chemicals
O=C(CSc1ccccc1)Nc1cccc(NC(=O)c2ccco2)c13 chemicals
C(=Nn1cnnc1)c1cccc(OCCOc2ccccc2)c12 chemicals
O=C(C=Cc1ccccc1)Nc1cccc(NC(=O)c2ccco2)c11 chemical
O=C(COc1ccccc1)Nc1cccc(NC(=O)c2cccs2)c11 chemical
O=C(NN=Cc1cccc(NC(=O)c2ccco2)c1)c1ccccc11 chemical
C(=Cc1ccccc1)COC1CCCC(COC2CCCO2)O11 chemical
O=C(OCc1ccccc1)Oc1cncc(C(=O)ON2C(=O)CCC2=O)c11 chemical
O=C(CCc1ccccc1)Nc1cccc(NC(=O)c2ccco2)c11 chemical
c1ccc(CCCOC2CCCC(COC3CCCO3)O2)cc11 chemical
O=S(=O)(C=Cc1ccccc1)Nc1cccc(S(=O)(=O)NC2=NCCC2)c11 chemical