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Murcko scaffold

Ring system with 4 rings and 32 atoms

8 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
32
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc(CN(CCCOc2ccccc2)CC(c2ccccc2)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CN(CCCOc2ccccc2)CC(c2ccccc2)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

3-(3-(((2-Chloro-3-(trifluoromethyl)phenyl)methyl)(2,2-diphenylethyl)amino)propoxy)benzeneacetic acid chemical structure, C33H31ClF3NO3, CAS 405911-09-3
3-(3-(((2-Chloro-3-(trifluoromethyl)phenyl)methyl)(2,2-diphenylethyl)amino)propoxy)benzeneacetic acid
CAS 405911-09-3C33H31ClF3NO3
Abequolixron chemical structure, C34H33ClF3NO3, CAS 610318-54-2
Abequolixron
CAS 610318-54-2C34H33ClF3NO3
2-(3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-diphenylethyl-amino]-propoxy}-phenyl)-acetamide chemical structure, C33H32ClF3N2O2, CAS 405910-78-3
2-(3-{3-[(2-Chloro-3-trifluoromethyl-benzyl)-diphenylethyl-amino]-propoxy}-phenyl)-acetamide
CAS 405910-78-3C33H32ClF3N2O2
GW3965 hydrochloride chemical structure, C33H32Cl2F3NO3, CAS 405911-17-3
GW3965 hydrochloride
CAS 405911-17-3C33H32Cl2F3NO3
3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy}-bromobenzene chemical structure, C31H28BrClF3NO, CAS 612494-90-3
3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy}-bromobenzene
CAS 612494-90-3C31H28BrClF3NO
Abequolixron hydrochloride chemical structure, C34H34Cl2F3NO3, CAS 610318-03-1
Abequolixron hydrochloride
CAS 610318-03-1C34H34Cl2F3NO3
(R)-2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]-3-methyl-propoxy}-phenyl)acetic acid methyl ester chemical structure, C35H35ClF3NO3, CAS 610319-02-3
(R)-2-(3-{3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]-3-methyl-propoxy}-phenyl)acetic acid methyl ester
CAS 610319-02-3C35H35ClF3NO3
Abequolixron zinc chemical structure, C68H64Cl2F6N2O6Zn, CAS 2648455-06-3
Abequolixron zinc
CAS 2648455-06-3C68H64Cl2F6N2O6Zn