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Murcko scaffold

N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-phenyloxamide scaffold

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
29
Chemicals
11
With full pages
4
Scaffold SMILES

O=C(NCCN1CCN(S(=O)(=O)c2ccccc2)CC1)C(=O)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-phenyloxamide page
Murcko scaffold O=C(NCCN1CCN(S(=O)(=O)c2ccccc2)CC1)C(=O)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

N'-(4-Ethylphenyl)-N-[2-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethyl]oxamide chemical structure, C22H27N5O6S, CAS 331759-23-0
N'-(4-Ethylphenyl)-N-[2-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethyl]oxamide
CAS 331759-23-0C22H27N5O6S
N-(4-Chlorophenyl)-N'-(2-{4-[(4-nitrophenyl)sulfonyl]piperazin-1-yl}ethyl)ethanediamide chemical structure, C20H22ClN5O6S, CAS 400737-77-1
N-(4-Chlorophenyl)-N'-(2-{4-[(4-nitrophenyl)sulfonyl]piperazin-1-yl}ethyl)ethanediamide
CAS 400737-77-1C20H22ClN5O6S
N'-(4-Methoxyphenyl)-N-[2-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethyl]oxamide chemical structure, C21H25N5O7S, CAS 333352-23-1
N'-(4-Methoxyphenyl)-N-[2-[4-(4-nitrophenyl)sulfonylpiperazin-1-yl]ethyl]oxamide
CAS 333352-23-1C21H25N5O7S
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(4-ethylphenyl)oxamide chemical structure, C22H28N4O4S, CAS 332026-58-1
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(4-ethylphenyl)oxamide
CAS 332026-58-1C22H28N4O4S
N-[2-[4-(4-Nitrophenyl)sulfonylpiperazin-1-yl]ethyl]-N'-phenyloxamide chemical structure, C20H23N5O6S, CAS 6063-80-5
N-[2-[4-(4-Nitrophenyl)sulfonylpiperazin-1-yl]ethyl]-N'-phenyloxamide
CAS 6063-80-5C20H23N5O6S
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(4-ethoxyphenyl)oxamide chemical structure, C22H28N4O5S, CAS 341954-68-5
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(4-ethoxyphenyl)oxamide
CAS 341954-68-5C22H28N4O5S
N'-(3,4-Dimethylphenyl)-N-[2-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]ethyl]oxamide chemical structure, C22H27FN4O4S, CAS 488086-69-7
N'-(3,4-Dimethylphenyl)-N-[2-[4-(4-fluorophenyl)sulfonylpiperazin-1-yl]ethyl]oxamide
CAS 488086-69-7C22H27FN4O4S
N-[2-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]ethyl]-N'-(4-fluorophenyl)oxamide chemical structure, C20H22ClFN4O4S, CAS 309935-69-1
N-[2-[4-(4-Chlorophenyl)sulfonylpiperazin-1-yl]ethyl]-N'-(4-fluorophenyl)oxamide
CAS 309935-69-1C20H22ClFN4O4S
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(3,4-dimethylphenyl)oxamide chemical structure, C22H28N4O4S, CAS 496941-32-3
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(3,4-dimethylphenyl)oxamide
CAS 496941-32-3C22H28N4O4S
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-phenyloxamide chemical structure, C20H24N4O4S, CAS 331849-71-9
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-phenyloxamide
CAS 331849-71-9C20H24N4O4S
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(4-bromo-3-methylphenyl)oxamide chemical structure, C21H25BrN4O4S, CAS 488102-26-7
N-[2-[4-(Benzenesulfonyl)piperazin-1-yl]ethyl]-N'-(4-bromo-3-methylphenyl)oxamide
CAS 488102-26-7C21H25BrN4O4S