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Murcko scaffold

Ring system with 4 rings and 27 atoms

22 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
22
With full pages
1
Scaffold SMILES

O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1SCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)c1nc(-c2ccco2)oc1SCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 22 of 22 chemicals

5-((2-Chlorobenzyl)thio)-2-(furan-2-yl)-4-(phenylsulfonyl)oxazole chemical structure, C20H14ClNO4S2, CAS 850928-48-2
5-((2-Chlorobenzyl)thio)-2-(furan-2-yl)-4-(phenylsulfonyl)oxazole
CAS 850928-48-2C20H14ClNO4S2
2-(Furan-2-yl)-5-((4-methylbenzyl)thio)-4-(phenylsulfonyl)oxazole chemical structure, C21H17NO4S2, CAS 850928-49-3
2-(Furan-2-yl)-5-((4-methylbenzyl)thio)-4-(phenylsulfonyl)oxazole
CAS 850928-49-3C21H17NO4S2
5-((4-Fluorobenzyl)thio)-2-(furan-2-yl)-4-tosyloxazole chemical structure, C21H16FNO4S2, CAS 686737-71-3
5-((4-Fluorobenzyl)thio)-2-(furan-2-yl)-4-tosyloxazole
CAS 686737-71-3C21H16FNO4S2
2-(2-Furyl)-5-[(4-methylbenzyl)thio]-4-[(4-methylphenyl)sulfonyl]-1,3-oxazole chemical structure, C22H19NO4S2, CAS 686737-77-9
2-(2-Furyl)-5-[(4-methylbenzyl)thio]-4-[(4-methylphenyl)sulfonyl]-1,3-oxazole
CAS 686737-77-9C22H19NO4S2
5-((2-Fluorobenzyl)thio)-2-(furan-2-yl)-4-tosyloxazole chemical structure, C21H16FNO4S2, CAS 686737-78-0
5-((2-Fluorobenzyl)thio)-2-(furan-2-yl)-4-tosyloxazole
CAS 686737-78-0C21H16FNO4S2
5-((4-Fluorobenzyl)thio)-4-((4-fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazole chemical structure, C20H13F2NO4S2, CAS 850928-68-6
5-((4-Fluorobenzyl)thio)-4-((4-fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazole
CAS 850928-68-6C20H13F2NO4S2
5-((2-Chlorobenzyl)thio)-4-((4-fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazole chemical structure, C20H13ClFNO4S2, CAS 850928-70-0
5-((2-Chlorobenzyl)thio)-4-((4-fluorophenyl)sulfonyl)-2-(furan-2-yl)oxazole
CAS 850928-70-0C20H13ClFNO4S2
4-[(4-Fluorophenyl)sulfonyl]-2-(2-furyl)-5-[(4-methylbenzyl)thio]-1,3-oxazole chemical structure, C21H16FNO4S2, CAS 850928-71-1
4-[(4-Fluorophenyl)sulfonyl]-2-(2-furyl)-5-[(4-methylbenzyl)thio]-1,3-oxazole
CAS 850928-71-1C21H16FNO4S2
5-[(2-Fluorobenzyl)thio]-4-[(4-fluorophenyl)sulfonyl]-2-(2-furyl)-1,3-oxazole chemical structure, C20H13F2NO4S2, CAS 850928-72-2
5-[(2-Fluorobenzyl)thio]-4-[(4-fluorophenyl)sulfonyl]-2-(2-furyl)-1,3-oxazole
CAS 850928-72-2C20H13F2NO4S2
4-[(4-Chlorophenyl)sulfonyl]-5-[(4-fluorobenzyl)thio]-2-(2-furyl)-1,3-oxazole chemical structure, C20H13ClFNO4S2, CAS 686738-05-6
4-[(4-Chlorophenyl)sulfonyl]-5-[(4-fluorobenzyl)thio]-2-(2-furyl)-1,3-oxazole
CAS 686738-05-6C20H13ClFNO4S2
5-((2-Chlorobenzyl)thio)-4-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)oxazole chemical structure, C20H13Cl2NO4S2, CAS 686738-09-0
5-((2-Chlorobenzyl)thio)-4-((4-chlorophenyl)sulfonyl)-2-(furan-2-yl)oxazole
CAS 686738-09-0C20H13Cl2NO4S2
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-((4-methylbenzyl)thio)oxazole chemical structure, C21H16ClNO4S2, CAS 686738-11-4
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-((4-methylbenzyl)thio)oxazole
CAS 686738-11-4C21H16ClNO4S2
4-(4-Chlorobenzenesulfonyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-2-(furan-2-yl)-1,3-oxazole chemical structure, C20H13ClFNO4S2, CAS 686738-13-6
4-(4-Chlorobenzenesulfonyl)-5-{[(2-fluorophenyl)methyl]sulfanyl}-2-(furan-2-yl)-1,3-oxazole
CAS 686738-13-6C20H13ClFNO4S2
4-((4-Bromophenyl)sulfonyl)-5-((4-fluorobenzyl)thio)-2-(furan-2-yl)oxazole chemical structure, C20H13BrFNO4S2, CAS 686738-34-1
4-((4-Bromophenyl)sulfonyl)-5-((4-fluorobenzyl)thio)-2-(furan-2-yl)oxazole
CAS 686738-34-1C20H13BrFNO4S2
4-((4-Bromophenyl)sulfonyl)-5-((2-chlorobenzyl)thio)-2-(furan-2-yl)oxazole chemical structure, C20H13BrClNO4S2, CAS 686738-36-3
4-((4-Bromophenyl)sulfonyl)-5-((2-chlorobenzyl)thio)-2-(furan-2-yl)oxazole
CAS 686738-36-3C20H13BrClNO4S2
4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)-5-((4-methylbenzyl)thio)oxazole chemical structure, C21H16BrNO4S2, CAS 686738-37-4
4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)-5-((4-methylbenzyl)thio)oxazole
CAS 686738-37-4C21H16BrNO4S2
4-((4-Bromophenyl)sulfonyl)-5-((2-fluorobenzyl)thio)-2-(furan-2-yl)oxazole chemical structure, C20H13BrFNO4S2, CAS 686738-38-5
4-((4-Bromophenyl)sulfonyl)-5-((2-fluorobenzyl)thio)-2-(furan-2-yl)oxazole
CAS 686738-38-5C20H13BrFNO4S2
2-(2-Furyl)-5-[(1-phenylethyl)thio]-4-(phenylsulfonyl)-1,3-oxazole chemical structure, C21H17NO4S2, CAS 830352-15-3
2-(2-Furyl)-5-[(1-phenylethyl)thio]-4-(phenylsulfonyl)-1,3-oxazole
CAS 830352-15-3C21H17NO4S2
2-(Furan-2-yl)-4-(4-methylbenzenesulfonyl)-5-[(1-phenylethyl)sulfanyl]-1,3-oxazole chemical structure, C22H19NO4S2, CAS 686737-73-5
2-(Furan-2-yl)-4-(4-methylbenzenesulfonyl)-5-[(1-phenylethyl)sulfanyl]-1,3-oxazole
CAS 686737-73-5C22H19NO4S2
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-((1-phenylethyl)thio)oxazole chemical structure, C21H16ClNO4S2, CAS 686738-07-8
4-((4-Chlorophenyl)sulfonyl)-2-(furan-2-yl)-5-((1-phenylethyl)thio)oxazole
CAS 686738-07-8C21H16ClNO4S2
4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)-5-((1-phenylethyl)thio)oxazole chemical structure, C21H16BrNO4S2, CAS 686738-35-2
4-((4-Bromophenyl)sulfonyl)-2-(furan-2-yl)-5-((1-phenylethyl)thio)oxazole
CAS 686738-35-2C21H16BrNO4S2
4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)-5-((1-phenylethyl)thio)oxazole chemical structure, C21H16FNO4S2, CAS 850928-69-7
4-((4-Fluorophenyl)sulfonyl)-2-(furan-2-yl)-5-((1-phenylethyl)thio)oxazole
CAS 850928-69-7C21H16FNO4S2