Murcko scaffold
Ring system with 3 rings and 23 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 23
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
O=C(NCc1ccccc1)C1CCN1C(=O)Cc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
Atecegatran
CAS 433937-74-7C21H21ClF2N4O4
Atecegatran metoxil
CAS 433937-93-0C22H23ClF2N4O5
![N-[(4-Carbamimidoylphenyl)methyl]-1-[2-[3-chloro-5-(difluoromethoxy)phenyl]-2-hydroxyacetyl]azetidine-2-carboxamide chemical structure, C21H21ClF2N4O4](/s/QTUUCFVBSVJGOH-UHFFFAOYSA-N.svg)
N-[(4-Carbamimidoylphenyl)methyl]-1-[2-[3-chloro-5-(difluoromethoxy)phenyl]-2-hydroxyacetyl]azetidine-2-carboxamide
C21H21ClF2N4O4
![2-Azetidinecarboxamide,N-[[4-(aminoiminomethyl)phenyl]methyl]-1-[(2R)-2-[3-chloro-5-(difluoromethoxy)phenyl]-2-hydroxyacetyl]- chemical structure, C21H21ClF2N4O4, CAS 917904-13-3](/s/QTUUCFVBSVJGOH-ZYMOGRSISA-N.svg)
2-Azetidinecarboxamide,N-[[4-(aminoiminomethyl)phenyl]methyl]-1-[(2R)-2-[3-chloro-5-(difluoromethoxy)phenyl]-2-hydroxyacetyl]-
CAS 917904-13-3C21H21ClF2N4O4
(R)-N-(4-Carbamimidoylbenzyl)-1-((R)-2-(3-chloro-5-(difluoromethoxy)phenyl)-2-hydroxyacetyl)azetidine-2-carboxamide
C21H21ClF2N4O4
Atecegatran TFA
CAS 433937-75-8C23H22ClF5N4O6
Related scaffolds
Same ring framework with different atoms or bond orders
