CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 22 atoms

20 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
20
With full pages
5
Scaffold SMILES

O=C(c1ccccc1)c1cnc2c(c1)COc1ccccc1-2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)c1cnc2c(c1)COc1ccccc1-2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 20 of 20 chemicals

(5-Chloro-2-hydroxyphenyl)(5H-chromeno[4,3-b]pyridin-3-yl)methanone chemical structure, C19H12ClNO3, CAS 178808-86-1
(5-Chloro-2-hydroxyphenyl)(5H-chromeno[4,3-b]pyridin-3-yl)methanone
CAS 178808-86-1C19H12ClNO3
5H-Chromeno[4,3-b]pyridin-3-yl(2-hydroxy-5-methylphenyl)methanone chemical structure, C20H15NO3, CAS 178808-85-0
5H-Chromeno[4,3-b]pyridin-3-yl(2-hydroxy-5-methylphenyl)methanone
CAS 178808-85-0C20H15NO3
(9-Chloro-5H-chromeno[4,3-b]pyridin-3-yl)(2-hydroxyphenyl)methanone chemical structure, C19H12ClNO3, CAS 178808-89-4
(9-Chloro-5H-chromeno[4,3-b]pyridin-3-yl)(2-hydroxyphenyl)methanone
CAS 178808-89-4C19H12ClNO3
(2-Hydroxy-5-methylphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone chemical structure, C21H17NO3, CAS 651727-48-9
(2-Hydroxy-5-methylphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone
CAS 651727-48-9C21H17NO3
(5-Bromo-2-hydroxyphenyl)(5H-chromeno[4,3-b]pyridin-3-yl)methanone chemical structure, C19H12BrNO3, CAS 178808-87-2
(5-Bromo-2-hydroxyphenyl)(5H-chromeno[4,3-b]pyridin-3-yl)methanone
CAS 178808-87-2C19H12BrNO3
(5-Chloro-2-hydroxyphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone chemical structure, C20H14ClNO3, CAS 501911-21-3
(5-Chloro-2-hydroxyphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone
CAS 501911-21-3C20H14ClNO3
(5-Bromo-2-hydroxyphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone chemical structure, C20H14BrNO3, CAS 651727-49-0
(5-Bromo-2-hydroxyphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone
CAS 651727-49-0C20H14BrNO3
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-chloro-2-hydroxyphenyl)methanone chemical structure, C19H11Cl2NO3, CAS 178808-91-8
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-chloro-2-hydroxyphenyl)methanone
CAS 178808-91-8C19H11Cl2NO3
Methanone, 5H-[1]benzopyrano[4,3-b]pyridin-3-yl(2-hydroxyphenyl)- chemical structure, C19H13NO3, CAS 178808-84-9
Methanone, 5H-[1]benzopyrano[4,3-b]pyridin-3-yl(2-hydroxyphenyl)-
CAS 178808-84-9C19H13NO3
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(2-hydroxy-5-methylphenyl)methanone chemical structure, C20H14ClNO3, CAS 178808-90-7
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(2-hydroxy-5-methylphenyl)methanone
CAS 178808-90-7C20H14ClNO3
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-bromo-2-hydroxyphenyl)methanone chemical structure, C19H11BrClNO3, CAS 178808-92-9
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-bromo-2-hydroxyphenyl)methanone
CAS 178808-92-9C19H11BrClNO3
(2-Hydroxyphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone chemical structure, C20H15NO3, CAS 501911-19-9
(2-Hydroxyphenyl)(9-methyl-5H-chromeno[4,3-b]pyridin-3-yl)methanone
CAS 501911-19-9C20H15NO3
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(2-hydroxyphenyl)methanone chemical structure, C19H12FNO3, CAS 651727-55-8
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(2-hydroxyphenyl)methanone
CAS 651727-55-8C19H12FNO3
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-fluoro-2-hydroxyphenyl)methanone chemical structure, C19H11F2NO3, CAS 651727-56-9
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-fluoro-2-hydroxyphenyl)methanone
CAS 651727-56-9C19H11F2NO3
(5-Fluoro-2-hydroxyphenyl)(9-methyl-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)methanone chemical structure, C20H14FNO3, CAS 651727-50-3
(5-Fluoro-2-hydroxyphenyl)(9-methyl-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)methanone
CAS 651727-50-3C20H14FNO3
5H-[1]Benzopyrano[4,3-b]pyridin-3-yl(5-fluoro-2-hydroxyphenyl)methanone chemical structure, C19H12FNO3, CAS 651727-47-8
5H-[1]Benzopyrano[4,3-b]pyridin-3-yl(5-fluoro-2-hydroxyphenyl)methanone
CAS 651727-47-8C19H12FNO3
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-fluoro-2-hydroxyphenyl)methanone chemical structure, C19H11ClFNO3, CAS 651727-52-5
(9-Chloro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-fluoro-2-hydroxyphenyl)methanone
CAS 651727-52-5C19H11ClFNO3
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(2-hydroxy-5-methylphenyl)methanone chemical structure, C20H14FNO3, CAS 651727-53-6
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(2-hydroxy-5-methylphenyl)methanone
CAS 651727-53-6C20H14FNO3
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-chloro-2-hydroxyphenyl)methanone chemical structure, C19H11ClFNO3, CAS 651727-54-7
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-chloro-2-hydroxyphenyl)methanone
CAS 651727-54-7C19H11ClFNO3
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-bromo-2-hydroxyphenyl)methanone chemical structure, C19H11BrFNO3, CAS 924986-85-6
(9-Fluoro-5H-[1]benzopyrano[4,3-b]pyridin-3-yl)(5-bromo-2-hydroxyphenyl)methanone
CAS 924986-85-6C19H11BrFNO3