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Murcko scaffold

Ring system with 5 rings and 29 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
29
Chemicals
10
With full pages
3
Scaffold SMILES

O=S(=O)(c1ccccc1)N1CN(Cc2ccccc2)c2nc3ccccc3nc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)N1CN(Cc2ccccc2)c2nc3ccccc3nc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-(4-Methoxybenzyl)-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C23H20N4O3S, CAS 847184-22-9
1-(4-Methoxybenzyl)-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 847184-22-9C23H20N4O3S
1-Benzyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C23H20N4O3S, CAS 845982-73-2
1-Benzyl-3-((4-methoxyphenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 845982-73-2C23H20N4O3S
1-(2-Methoxybenzyl)-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C23H20N4O3S, CAS 845989-07-3
1-(2-Methoxybenzyl)-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 845989-07-3C23H20N4O3S
1-((4-Methoxyphenyl)sulfonyl)-3-(4-methylbenzyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C24H22N4O3S, CAS 848213-87-6
1-((4-Methoxyphenyl)sulfonyl)-3-(4-methylbenzyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848213-87-6C24H22N4O3S
1-(4-Methoxybenzyl)-3-tosyl-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C24H22N4O3S, CAS 848681-73-2
1-(4-Methoxybenzyl)-3-tosyl-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848681-73-2C24H22N4O3S
1-(4-Fluorobenzyl)-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C22H17FN4O2S, CAS 848766-64-3
1-(4-Fluorobenzyl)-3-(phenylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848766-64-3C22H17FN4O2S
1-(4-Fluorobenzyl)-3-(m-tolylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C23H19FN4O2S, CAS 848728-14-3
1-(4-Fluorobenzyl)-3-(m-tolylsulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848728-14-3C23H19FN4O2S
1-(2-Methoxybenzyl)-3-tosyl-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C24H22N4O3S, CAS 848734-66-7
1-(2-Methoxybenzyl)-3-tosyl-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 848734-66-7C24H22N4O3S
1-Benzyl-3-(4-fluorophenyl)sulfonyl-2H-imidazo[4,5-b]quinoxaline chemical structure, C22H17FN4O2S, CAS 849913-98-0
1-Benzyl-3-(4-fluorophenyl)sulfonyl-2H-imidazo[4,5-b]quinoxaline
CAS 849913-98-0C22H17FN4O2S
1-(4-Fluorobenzyl)-3-((4-fluorophenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline chemical structure, C22H16F2N4O2S, CAS 844651-27-0
1-(4-Fluorobenzyl)-3-((4-fluorophenyl)sulfonyl)-2,3-dihydro-1H-imidazo[4,5-b]quinoxaline
CAS 844651-27-0C22H16F2N4O2S