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Murcko scaffold

Ring system with 3 rings and 14 atoms

48 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
14
Chemicals
48
With full pages
2
Scaffold SMILES

c1ccc(-c2cc(C3CC3)on2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2cc(C3CC3)on2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 48 chemicals

5-Cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylic acid chemical structure, C13H11NO3, CAS 943130-42-5
5-Cyclopropyl-3-phenyl-1,2-oxazole-4-carboxylic acid
CAS 943130-42-5C13H11NO3
(5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methanol chemical structure, C13H11Cl2NO2, CAS 946426-89-7
(5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methanol
CAS 946426-89-7C13H11Cl2NO2
Ethyl 5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate chemical structure, C15H13Cl2NO3, CAS 1020569-65-6
Ethyl 5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylate
CAS 1020569-65-6C15H13Cl2NO3
Methyl 5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazole-4-carboxylate chemical structure, C14H11Cl2NO3, CAS 946426-88-6
Methyl 5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazole-4-carboxylate
CAS 946426-88-6C14H11Cl2NO3
4-(Bromomethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole chemical structure, C13H10BrCl2NO, CAS 946426-94-4
4-(Bromomethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazole
CAS 946426-94-4C13H10BrCl2NO
Methyl 5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylate chemical structure, C15H12F3NO4, CAS 1103500-32-8
Methyl 5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylate
CAS 1103500-32-8C15H12F3NO4
4-(Bromomethyl)-5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]isoxazole chemical structure, C14H11BrF3NO2, CAS 946427-86-7
4-(Bromomethyl)-5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]isoxazole
CAS 946427-86-7C14H11BrF3NO2
5-Cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-4-isoxazolemethanol chemical structure, C14H12F3NO3, CAS 946426-90-0
5-Cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-4-isoxazolemethanol
CAS 946426-90-0C14H12F3NO3
4-(Chloromethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazole chemical structure, C13H10Cl3NO, CAS 1268245-50-6
4-(Chloromethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazole
CAS 1268245-50-6C13H10Cl3NO
5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylic Acid chemical structure, C13H9Cl2NO3, CAS 2191434-19-0
5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carboxylic Acid
CAS 2191434-19-0C13H9Cl2NO3
5-Cyclopropyl-3-(o-tolyl)isoxazole-4-carboxylic acid chemical structure, C14H13NO3, CAS 2832324-66-8
5-Cyclopropyl-3-(o-tolyl)isoxazole-4-carboxylic acid
CAS 2832324-66-8C14H13NO3
5-Cyclopropyl-3-[2-(difluoromethoxy)phenyl]-4-isoxazolemethanol chemical structure, C14H13F2NO3, CAS 1383825-27-1
5-Cyclopropyl-3-[2-(difluoromethoxy)phenyl]-4-isoxazolemethanol
CAS 1383825-27-1C14H13F2NO3
4-(Chloromethyl)-5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole chemical structure, C14H11ClF3NO2, CAS 1952348-17-2
4-(Chloromethyl)-5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole
CAS 1952348-17-2C14H11ClF3NO2
5-Cyclopropyl-3-[2-(trifluoromethyl)phenyl]-4-isoxazolemethanol chemical structure, C14H12F3NO2, CAS 1383825-25-9
5-Cyclopropyl-3-[2-(trifluoromethyl)phenyl]-4-isoxazolemethanol
CAS 1383825-25-9C14H12F3NO2
4-(Chloromethyl)-5-cyclopropyl-3-(2,6-dichloro-4-fluorophenyl)isoxazole chemical structure, C13H9Cl3FNO, CAS 2165357-54-8
4-(Chloromethyl)-5-cyclopropyl-3-(2,6-dichloro-4-fluorophenyl)isoxazole
CAS 2165357-54-8C13H9Cl3FNO
5-Cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylic acid chemical structure, C14H10F3NO4, CAS 2191433-23-3
5-Cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylic acid
CAS 2191433-23-3C14H10F3NO4
Methyl 5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]-4-isoxazolecarboxylate chemical structure, C15H12F3NO3, CAS 1383825-22-6
Methyl 5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]-4-isoxazolecarboxylate
CAS 1383825-22-6C15H12F3NO3
5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carbaldehyde chemical structure, C13H9Cl2NO2, CAS 2222234-77-5
5-Cyclopropyl-3-(2,6-dichlorophenyl)isoxazole-4-carbaldehyde
CAS 2222234-77-5C13H9Cl2NO2
(5-Cyclopropyl-3-phenylisoxazol-4-yl)methanol chemical structure, C13H13NO2, CAS 2306261-13-0
(5-Cyclopropyl-3-phenylisoxazol-4-yl)methanol
CAS 2306261-13-0C13H13NO2
4-(Bromomethyl)-5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]isoxazole chemical structure, C14H11BrF3NO, CAS 1383825-31-7
4-(Bromomethyl)-5-cyclopropyl-3-[2-(trifluoromethyl)phenyl]isoxazole
CAS 1383825-31-7C14H11BrF3NO
4-Bromo-2-(5-cyclopropyl-3-isoxazolyl)phenol chemical structure, C12H10BrNO2, CAS 2354322-97-5
4-Bromo-2-(5-cyclopropyl-3-isoxazolyl)phenol
CAS 2354322-97-5C12H10BrNO2
Ethyl 5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylate chemical structure, C16H14F3NO4, CAS 2247973-73-3
Ethyl 5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazole-4-carboxylate
CAS 2247973-73-3C16H14F3NO4
5-Cyclopropyl-3-(2-(trifluoromethyl)phenyl)isoxazole-4-carboxylic acid chemical structure, C14H10F3NO3, CAS 2195385-21-6
5-Cyclopropyl-3-(2-(trifluoromethyl)phenyl)isoxazole-4-carboxylic acid
CAS 2195385-21-6C14H10F3NO3
4-(Chloromethyl)-5-cyclopropyl-3-(2,6-dichloro-4-methoxyphenyl)isoxazole chemical structure, C14H12Cl3NO2, CAS 2195388-28-2
4-(Chloromethyl)-5-cyclopropyl-3-(2,6-dichloro-4-methoxyphenyl)isoxazole
CAS 2195388-28-2C14H12Cl3NO2