Murcko scaffold
Ring system with 5 rings and 26 atoms
37 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 26
- Chemicals
- 37
- With full pages
- 3
Scaffold SMILES
c1ccc(N=c2oc3ccccc3cc2-c2nc3ccccc3[nH]2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold c1ccc(N=c2oc3ccccc3cc2-c2nc3ccccc3[nH]2)cc1](/scaffold/KACQQKWMCJWUHB-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 37 of 37 chemicals
![N-[(2Z)-3-(1H-Benzimidazol-2-yl)-6-bromo-2H-chromen-2-ylidene]-2-methoxyaniline chemical structure, C23H16BrN3O2, CAS 313966-62-0](/s/FOSIJFKMOGKKTI-UHFFFAOYSA-N.svg)
N-[(2Z)-3-(1H-Benzimidazol-2-yl)-6-bromo-2H-chromen-2-ylidene]-2-methoxyaniline
CAS 313966-62-0C23H16BrN3O2
![(Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-6-bromo-2H-chromen-2-ylidene)-4-fluoroaniline chemical structure, C22H13BrFN3O, CAS 313954-99-3](/s/TZXKGBDFDBDPOS-UHFFFAOYSA-N.svg)
(Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-6-bromo-2H-chromen-2-ylidene)-4-fluoroaniline
CAS 313954-99-3C22H13BrFN3O
(2Z)-3-(1H-1,3-Benzodiazol-2-yl)-6-bromo-N-(2-fluorophenyl)-2H-chromen-2-imine
CAS 313955-00-9C22H13BrFN3O
![Ethyl 4-{[(2z)-3-(1H-benzimidazol-2-yl)-6-methoxy-2H-chromen-2-ylidene]amino}benzoate chemical structure, C26H21N3O4, CAS 312706-97-1](/s/CCYIGQNCLXTSGT-UHFFFAOYSA-N.svg)
Ethyl 4-{[(2z)-3-(1H-benzimidazol-2-yl)-6-methoxy-2H-chromen-2-ylidene]amino}benzoate
CAS 312706-97-1C26H21N3O4
3-(1H-Benzimidazol-2-yl)-N-(2-chlorophenyl)chromen-2-imine
CAS 313243-17-3C22H14ClN3O
![N-[(2Z)-3-(1H-Benzimidazol-2-yl)-2H-chromen-2-ylidene]-2-methylaniline chemical structure, C23H17N3O, CAS 314035-48-8](/s/WFPGLINMIBVOOJ-UHFFFAOYSA-N.svg)
N-[(2Z)-3-(1H-Benzimidazol-2-yl)-2H-chromen-2-ylidene]-2-methylaniline
CAS 314035-48-8C23H17N3O
![Ethyl 4-[[3-(1H-benzimidazol-2-yl)-8-methoxychromen-2-ylidene]amino]benzoate chemical structure, C26H21N3O4, CAS 313234-47-8](/s/ROHVQLRGFZAKDV-UHFFFAOYSA-N.svg)
Ethyl 4-[[3-(1H-benzimidazol-2-yl)-8-methoxychromen-2-ylidene]amino]benzoate
CAS 313234-47-8C26H21N3O4
![N-[3-(1H-Benzimidazol-2-yl)-6-methoxy-2H-chromen-2-ylidene]-N-(4-methoxyphenyl)amine chemical structure, C24H19N3O3, CAS 1164499-69-7](/s/LSHHOSMKXZQGNT-UHFFFAOYSA-N.svg)
N-[3-(1H-Benzimidazol-2-yl)-6-methoxy-2H-chromen-2-ylidene]-N-(4-methoxyphenyl)amine
CAS 1164499-69-7C24H19N3O3
3-(1H-Benzimidazol-2-yl)-6-methoxy-N-(3-methoxyphenyl)chromen-2-imine
CAS 1164474-00-3C24H19N3O3
3-(1H-Benzimidazol-2-yl)-6-bromo-N-phenylchromen-2-imine
CAS 313956-50-2C22H14BrN3O
3-(1H-Benzimidazol-2-yl)-N-(2-chlorophenyl)-6-methoxychromen-2-imine
CAS 313243-18-4C23H16ClN3O2
![3-(1H-Benzimidazol-2-yl)-6-bromo-N-[4-(trifluoromethyl)phenyl]chromen-2-imine chemical structure, C23H13BrF3N3O, CAS 330158-08-2](/s/BFIJJKRMINUGIS-UHFFFAOYSA-N.svg)
3-(1H-Benzimidazol-2-yl)-6-bromo-N-[4-(trifluoromethyl)phenyl]chromen-2-imine
CAS 330158-08-2C23H13BrF3N3O
3-(1H-Benzimidazol-2-yl)-6-bromo-N-(2-chlorophenyl)chromen-2-imine
CAS 313243-20-8C22H13BrClN3O
3-(1H-Benzimidazol-2-yl)-N-(3-fluorophenyl)-6-methoxychromen-2-imine
CAS 313954-92-6C23H16FN3O2
![3-[[3-(1H-Benzimidazol-2-yl)-7-methoxychromen-2-ylidene]amino]benzonitrile chemical structure, C24H16N4O2, CAS 324021-08-1](/s/DSZNVWNQKGPPDI-UHFFFAOYSA-N.svg)
3-[[3-(1H-Benzimidazol-2-yl)-7-methoxychromen-2-ylidene]amino]benzonitrile
CAS 324021-08-1C24H16N4O2
![4-{[(2Z)-3-(1H-1,3-Benzodiazol-2-yl)-8-methoxy-2H-chromen-2-ylidene]amino}benzamide chemical structure, C24H18N4O3, CAS 1321751-61-4](/s/BKAALDUZCPDYJK-UHFFFAOYSA-N.svg)
4-{[(2Z)-3-(1H-1,3-Benzodiazol-2-yl)-8-methoxy-2H-chromen-2-ylidene]amino}benzamide
CAS 1321751-61-4C24H18N4O3
(2Z)-3-(1H-1,3-Benzodiazol-2-yl)-6-methoxy-N-(2-methylphenyl)-2H-chromen-2-imine
CAS 330837-16-6C24H19N3O2
3-(1H-Benzimidazol-2-yl)-N-(4-fluorophenyl)-6-methoxychromen-2-imine
CAS 313954-91-5C23H16FN3O2
3-(1H-Benzimidazol-2-yl)-6-methoxy-N-phenylchromen-2-imine
CAS 1164532-48-2C23H17N3O2
![3-[[3-(1H-Benzimidazol-2-yl)-8-methoxychromen-2-ylidene]amino]benzonitrile chemical structure, C24H16N4O2, CAS 1321732-93-7](/s/AKITZMMDDXHTKZ-UHFFFAOYSA-N.svg)
3-[[3-(1H-Benzimidazol-2-yl)-8-methoxychromen-2-ylidene]amino]benzonitrile
CAS 1321732-93-7C24H16N4O2
![(Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-2H-chromen-2-ylidene)-4-(trifluoromethyl)aniline chemical structure, C23H14F3N3O, CAS 313668-90-5](/s/ULYKAHYOWCYSHP-UHFFFAOYSA-N.svg)
(Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-2H-chromen-2-ylidene)-4-(trifluoromethyl)aniline
CAS 313668-90-5C23H14F3N3O
(2Z)-3-(1H-1,3-Benzodiazol-2-yl)-N-(2,4-dichlorophenyl)-6-methoxy-2H-chromen-2-imine
CAS 1321734-37-5C23H15Cl2N3O2
![N-[(2Z)-3-(1H-Benzimidazol-2-yl)-6-chloro-2H-chromen-2-ylidene]-2-methylaniline chemical structure, C23H16ClN3O, CAS 444770-51-8](/s/LTFUKRKHLADZGS-UHFFFAOYSA-N.svg)
N-[(2Z)-3-(1H-Benzimidazol-2-yl)-6-chloro-2H-chromen-2-ylidene]-2-methylaniline
CAS 444770-51-8C23H16ClN3O
![(Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-6-bromo-2H-chromen-2-ylidene)-3-fluoroaniline chemical structure, C22H13BrFN3O, CAS 313233-03-3](/s/SNPCCQRIZYMGCX-UHFFFAOYSA-N.svg)
(Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-6-bromo-2H-chromen-2-ylidene)-3-fluoroaniline
CAS 313233-03-3C22H13BrFN3O
- (2Z)-3-(1H-1,3-Benzodiazol-2-yl)-N-[3-(trifluoromethyl)phenyl]-2H-chromen-2-imine313668-92-7C23H14F3N3O
- 4-[[3-(1H-Benzimidazol-2-yl)-8-methoxychromen-2-ylidene]amino]benzonitrile313954-48-2C24H16N4O2
- 3-(1H-Benzimidazol-2-yl)-N-(4-fluorophenyl)-7-methoxychromen-2-imine313233-01-1C23H16FN3O2
- 3-(1H-Benzimidazol-2-yl)-6-methoxy-N-(3-methylphenyl)chromen-2-imine330837-17-7C24H19N3O2
- (Z)-N-(3-(1H-Benzo[d]imidazol-2-yl)-8-methoxy-2H-chromen-2-ylidene)-3-(trifluoromethyl)aniline313954-50-6C24H16F3N3O2
- N-[(2Z)-3-(1H-Benzimidazol-2-yl)-8-methoxy-2H-chromen-2-ylidene]-2-methylaniline313956-51-3C24H19N3O2
- (2Z)-3-(1H-1,3-Benzodiazol-2-yl)-6-methoxy-N-(2-methoxyphenyl)-2H-chromen-2-imine389076-03-3C24H19N3O3
- (2Z)-3-(1H-1,3-Benzodiazol-2-yl)-6-bromo-N-(4-methylphenyl)-2H-chromen-2-imine330158-04-8C23H16BrN3O
- 4-{[(2Z)-3-(1H-1,3-Benzodiazol-2-yl)-7-methoxy-2H-chromen-2-ylidene]amino}benzamide1322298-43-0C24H18N4O3
- (2Z)-3-(1H-1,3-Benzodiazol-2-yl)-N-(2,4-dichlorophenyl)-8-methoxy-2H-chromen-2-imine330837-25-7C23H15Cl2N3O2
- (2Z)-3-(1H-1,3-Benzodiazol-2-yl)-7-ethoxy-N-(2-fluorophenyl)-2H-chromen-2-imine330837-22-4C24H18FN3O2
- 3-(1H-Benzimidazol-2-yl)-6-hexyl-2-(2-methoxyanilino)chromen-7-one313976-80-6C29H29N3O3
- (2Z)-3-(1H-1,3-Benzodiazol-2-yl)-N-(3-fluorophenyl)-7-methoxy-2H-chromen-2-imine2321338-20-7C23H16FN3O2