CompoundList
Sign in
Murcko scaffold

Ring system with 6 rings and 20 atoms

19 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
20
Chemicals
19
With full pages
8
Scaffold SMILES

O=C1C2CN3CC1CN(C2)C3c1c[nH]c2ccccc12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C2CN3CC1CN(C2)C3c1c[nH]c2ccccc12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1H-indol-3-yl)- chemical structure, C18H21N3O, CAS 108790-75-6
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1H-indol-3-yl)-
CAS 108790-75-6C18H21N3O
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(5-methoxy-1H-indol-3-yl)- chemical structure, C19H23N3O2, CAS 134828-31-2
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(5-methoxy-1H-indol-3-yl)-
CAS 134828-31-2C19H23N3O2
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1,2-dimethyl-1H-indol-3-yl)- chemical structure, C20H25N3O, CAS 134828-30-1
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1,2-dimethyl-1H-indol-3-yl)-
CAS 134828-30-1C20H25N3O
5,7-Diethyl-2-(1H-indol-3-yl)-1,3-diazaadamantan-6-one chemical structure, C20H25N3O, CAS 354992-85-1
5,7-Diethyl-2-(1H-indol-3-yl)-1,3-diazaadamantan-6-one
CAS 354992-85-1C20H25N3O
5,7-Diethyl-2-(2-methyl-1H-indol-3-yl)-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one chemical structure, C21H27N3O, CAS 633286-28-9
5,7-Diethyl-2-(2-methyl-1H-indol-3-yl)-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one
CAS 633286-28-9C21H27N3O
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1-methyl-1H-indol-3-yl)- chemical structure, C19H23N3O, CAS 134828-28-7
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1-methyl-1H-indol-3-yl)-
CAS 134828-28-7C19H23N3O
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(2-methyl-1H-indol-3-yl)- chemical structure, C19H23N3O, CAS 134828-29-8
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(2-methyl-1H-indol-3-yl)-
CAS 134828-29-8C19H23N3O
1H-Indole-5-sulfonamide, N,N-dimethyl-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)- chemical structure, C20H26N4O3S, CAS 134828-33-4
1H-Indole-5-sulfonamide, N,N-dimethyl-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-
CAS 134828-33-4C20H26N4O3S
1H-Indole-5-sulfonamide, 3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-N,N,1-trimethyl- chemical structure, C21H28N4O3S, CAS 134828-34-5
1H-Indole-5-sulfonamide, 3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-N,N,1-trimethyl-
CAS 134828-34-5C21H28N4O3S
2-(1H-Indol-3-yl)-5,7-diisopropyl-1,3-diazaadamantan-6-one chemical structure, C22H29N3O, CAS 354992-86-2
2-(1H-Indol-3-yl)-5,7-diisopropyl-1,3-diazaadamantan-6-one
CAS 354992-86-2C22H29N3O
5,7-Diethyl-2-(5-methoxy-1H-indol-3-yl)-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one chemical structure, C21H27N3O2, CAS 698980-37-9
5,7-Diethyl-2-(5-methoxy-1H-indol-3-yl)-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one
CAS 698980-37-9C21H27N3O2
5,7-Diethyl-2-(1-ethyl-1H-indol-3-yl)-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one chemical structure, C22H29N3O, CAS 698980-43-7
5,7-Diethyl-2-(1-ethyl-1H-indol-3-yl)-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one
CAS 698980-43-7C22H29N3O
2-(1-Ethyl-2-methyl-1H-indol-3-yl)-5,7-dimethyl-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one chemical structure, C21H27N3O, CAS 698980-57-3
2-(1-Ethyl-2-methyl-1H-indol-3-yl)-5,7-dimethyl-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one
CAS 698980-57-3C21H27N3O
1H-Indole-5-sulfonamide, N,N-diethyl-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)- chemical structure, C22H30N4O3S, CAS 134828-35-6
1H-Indole-5-sulfonamide, N,N-diethyl-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-
CAS 134828-35-6C22H30N4O3S
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1,2-dimethyl-5-methoxy-1H-indol-3-yl)- chemical structure, C21H27N3O2, CAS 134828-32-3
1,3-Diazatricyclo(3.3.1.1(sup 3,7))decan-6-one, 5,7-dimethyl-2-(1,2-dimethyl-5-methoxy-1H-indol-3-yl)-
CAS 134828-32-3C21H27N3O2
1H-Indole-5-sulfonamide, N,N-diethyl-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-1-methyl- chemical structure, C23H32N4O3S, CAS 134828-36-7
1H-Indole-5-sulfonamide, N,N-diethyl-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-1-methyl-
CAS 134828-36-7C23H32N4O3S
1H-Indole-5-sulfonamide, N,N-bis(2-chloroethyl)-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)- chemical structure, C22H28Cl2N4O3S, CAS 134828-37-8
1H-Indole-5-sulfonamide, N,N-bis(2-chloroethyl)-3-(5,7-dimethyl-6-oxo-1,3-diazatricyclo(3.3.1.1(sup 3,7))dec-2-yl)-
CAS 134828-37-8C22H28Cl2N4O3S
5-Ethyl-2-(1H-indol-3-yl)-7-methyl-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one chemical structure, C19H23N3O, CAS 956986-32-6
5-Ethyl-2-(1H-indol-3-yl)-7-methyl-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one
CAS 956986-32-6C19H23N3O
5-Ethyl-2-(5-methoxy-1H-indol-3-yl)-7-methyl-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one chemical structure, C20H25N3O2, CAS 956756-72-2
5-Ethyl-2-(5-methoxy-1H-indol-3-yl)-7-methyl-1,3-diazatricyclo[3.3.1.1~3,7~]decan-6-one
CAS 956756-72-2C20H25N3O2