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Murcko scaffold

Ring system with 3 rings and 14 atoms

21 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 14
Chemicals: 21
With full pages: 3

Scaffold SMILES

c1ccc2nc3c(cc2c1)CNCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1ccc2nc3c(cc2c1)CNCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

2-Methyl-1H,2H,3H,4H-benzo(b)1,6-naphthyridine-10-carboxylic acid chemical structure, C14H14N2O2, CAS 380432-30-4

2-Methyl-1H,2H,3H,4H-benzo(b)1,6-naphthyridine-10-carboxylic acid

CAS 380432-30-4C₁₄H₁₄N₂O₂

8-Fluoro-2-methyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxamide chemical structure, C14H14FN3O, CAS 844882-85-5

8-Fluoro-2-methyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxamide

CAS 844882-85-5C₁₄H₁₄FN₃O

2-Ethyl-1,2,3,4-tetrahydro-benzo[b][1,6]naphthyridine-10-carboxylic acid chemical structure, C15H16N2O2, CAS 519150-65-3

2-Ethyl-1,2,3,4-tetrahydro-benzo[b][1,6]naphthyridine-10-carboxylic acid

CAS 519150-65-3C₁₅H₁₆N₂O₂

Hydrazinecarboxamide, 2-(7-chloro-1,2,3,4-tetrahydro-2-propylbenzo(b)(1,6)naphthyridin-10-yl)- chemical structure, C16H20ClN5O, CAS 177406-18-7

Hydrazinecarboxamide, 2-(7-chloro-1,2,3,4-tetrahydro-2-propylbenzo(b)(1,6)naphthyridin-10-yl)-

CAS 177406-18-7C₁₆H₂₀ClN₅O

2-(tert-Butylcarbonyl)-1,2,3,4-tetrahydrobenzo(b)(1,6)naphthyridine-10-carboxylic acid chemical structure, C18H20N2O3, CAS 887432-93-1

2-(tert-Butylcarbonyl)-1,2,3,4-tetrahydrobenzo(b)(1,6)naphthyridine-10-carboxylic acid

CAS 887432-93-1C₁₈H₂₀N₂O₃

1H,2H,3H,4H-Benzo[B]1,6-naphthyridin-10-amine chemical structure, C12H13N3, CAS 134315-04-1

1H,2H,3H,4H-Benzo[B]1,6-naphthyridin-10-amine

CAS 134315-04-1C₁₂H₁₃N₃

2-Methyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridin-10-amine chemical structure, C13H15N3, CAS 21805-14-1

2-Methyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridin-10-amine

CAS 21805-14-1C₁₃H₁₅N₃

2-Isopropyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carbonitrile chemical structure, C16H17N3, CAS 849587-90-2

2-Isopropyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carbonitrile

CAS 849587-90-2C₁₆H₁₇N₃

Benzo[b][1,6]naphthyridine-10-carbonitrile, 1,2,3,4-tetrahydro-2-methyl- chemical structure, C14H13N3, CAS 850464-28-7

Benzo[b][1,6]naphthyridine-10-carbonitrile, 1,2,3,4-tetrahydro-2-methyl-

CAS 850464-28-7C₁₄H₁₃N₃

Benzo[b][1,6]naphthyridine, 10-chloro-1,2,3,4-tetrahydro-2-methyl- chemical structure, C13H13ClN2, CAS 59194-39-7

Benzo[b][1,6]naphthyridine, 10-chloro-1,2,3,4-tetrahydro-2-methyl-

CAS 59194-39-7C₁₃H₁₃ClN₂

1,2,3,4-Tetrahydro-2,8-dimethylbenzo[b][1,6]naphthyridine-10-carboxylic acid chemical structure, C15H16N2O2, CAS 953900-65-7

1,2,3,4-Tetrahydro-2,8-dimethylbenzo[b][1,6]naphthyridine-10-carboxylic acid

CAS 953900-65-7C₁₅H₁₆N₂O₂

8-Fluoro-2-methyl-1H,2H,3H,4H-benzo[B]1,6-naphthyridine-10-carboxylic acid chemical structure, C14H13FN2O2, CAS 1016501-46-4

8-Fluoro-2-methyl-1H,2H,3H,4H-benzo[B]1,6-naphthyridine-10-carboxylic acid

CAS 1016501-46-4C₁₄H₁₃FN₂O₂

2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxylic acid chemical structure, C18H20N2O4, CAS 219536-91-1

2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carboxylic acid

CAS 219536-91-1C₁₈H₂₀N₂O₄

2-Ethyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridine-10-carboxylic acid hydrochloride chemical structure, C15H17ClN2O2, CAS 1170283-86-9

2-Ethyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridine-10-carboxylic acid hydrochloride

CAS 1170283-86-9C₁₅H₁₇ClN₂O₂

2-Methyl-6-(propan-2-yl)-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carbonitrile chemical structure, C17H19N3, CAS 1368141-76-7

2-Methyl-6-(propan-2-yl)-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine-10-carbonitrile

CAS 1368141-76-7C₁₇H₁₉N₃

2-(tert-Butoxycarbonyl)-6-chloro-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridine-10-carboxylic acid chemical structure, C18H19ClN2O4, CAS 1443978-03-7

2-(tert-Butoxycarbonyl)-6-chloro-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridine-10-carboxylic acid

CAS 1443978-03-7C₁₈H₁₉ClN₂O₄

1-(10-Ethoxy-8-methyl-3,4-dihydro-1H-benzo[b][1,6]naphthyridin-2-yl)-2,2,2-trifluoro-ethanone chemical structure, C17H17F3N2O2, CAS 1553969-12-2

1-(10-Ethoxy-8-methyl-3,4-dihydro-1H-benzo[b][1,6]naphthyridin-2-yl)-2,2,2-trifluoro-ethanone

CAS 1553969-12-2C₁₇H₁₇F₃N₂O₂

Methyl 8-fluoro-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridine-10-carboxylate chemical structure, C14H13FN2O2, CAS 1895002-63-7

Methyl 8-fluoro-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridine-10-carboxylate

CAS 1895002-63-7C₁₄H₁₃FN₂O₂

Methyl 8-chloro-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridine-10-carboxylate chemical structure, C14H13ClN2O2, CAS 1888803-69-7

Methyl 8-chloro-1,2,3,4-tetrahydrobenzo[b]-1,6-naphthyridine-10-carboxylate

CAS 1888803-69-7C₁₄H₁₃ClN₂O₂

2-Methyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridine-10-carboxylic acid dihydrochloride chemical structure, C14H16Cl2N2O2, CAS 2109412-34-0

2-Methyl-1H,2H,3H,4H-benzo[b]1,6-naphthyridine-10-carboxylic acid dihydrochloride

CAS 2109412-34-0C₁₄H₁₆Cl₂N₂O₂

6-Bromo-2-methyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine chemical structure, C13H13BrN2, CAS 2598264-95-8

6-Bromo-2-methyl-1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine

CAS 2598264-95-8C₁₃H₁₃BrN₂