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Murcko scaffold

N1-benzyl-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide scaffold

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
27
Chemicals
7
With full pages
5
Scaffold SMILES

O=C(NCc1ccccc1)C(=O)NCC1OCCN1S(=O)(=O)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N1-benzyl-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide page
Murcko scaffold O=C(NCc1ccccc1)C(=O)NCC1OCCN1S(=O)(=O)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

N'-[(4-Methylphenyl)methyl]-N-{[3-(thiophene-2-sulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide chemical structure, C18H21N3O5S2, CAS 874804-63-4
N'-[(4-Methylphenyl)methyl]-N-{[3-(thiophene-2-sulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide
CAS 874804-63-4C18H21N3O5S2
N1-benzyl-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C17H19N3O5S2, CAS 874804-62-3
N1-benzyl-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 874804-62-3C17H19N3O5S2
N1-(4-methoxybenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C18H21N3O6S2, CAS 874804-77-0
N1-(4-methoxybenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 874804-77-0C18H21N3O6S2
N'-[(4-Fluorophenyl)methyl]-N-{[3-(thiophene-2-sulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide chemical structure, C17H18FN3O5S2, CAS 874804-72-5
N'-[(4-Fluorophenyl)methyl]-N-{[3-(thiophene-2-sulfonyl)-1,3-oxazolidin-2-yl]methyl}ethanediamide
CAS 874804-72-5C17H18FN3O5S2
N1-(4-chlorobenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C17H18ClN3O5S2, CAS 874804-64-5
N1-(4-chlorobenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 874804-64-5C17H18ClN3O5S2
N1-(2-chlorobenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C17H18ClN3O5S2, CAS 874804-93-0
N1-(2-chlorobenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 874804-93-0C17H18ClN3O5S2
N1-(2-methoxybenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide chemical structure, C18H21N3O6S2, CAS 874804-88-3
N1-(2-methoxybenzyl)-N2-((3-(thiophen-2-ylsulfonyl)oxazolidin-2-yl)methyl)oxalamide
CAS 874804-88-3C18H21N3O6S2