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Murcko scaffold

Ring system with 3 rings and 21 atoms

11 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
11
With full pages
4
Scaffold SMILES

C(=NNc1ccnc(-c2ccccc2)n1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=NNc1ccnc(-c2ccccc2)n1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

2,3,4,5,6-Pentafluorobenzaldehyde 2-[2-(2-hydroxyphenyl)-6-methyl-4-pyrimidinyl]hydrazone chemical structure, C18H11F5N4O, CAS 300358-35-4
2,3,4,5,6-Pentafluorobenzaldehyde 2-[2-(2-hydroxyphenyl)-6-methyl-4-pyrimidinyl]hydrazone
CAS 300358-35-4C18H11F5N4O
N-[(E)-1-(4-Ethylphenyl)ethylideneamino]-6-methyl-2-phenylpyrimidin-4-amine chemical structure, C21H22N4, CAS 5340-74-9
N-[(E)-1-(4-Ethylphenyl)ethylideneamino]-6-methyl-2-phenylpyrimidin-4-amine
CAS 5340-74-9C21H22N4
1-(4-Aminophenyl)ethanone (5-allyl-6-methyl-2-phenyl-4-pyrimidinyl)hydrazone chemical structure, C22H23N5, CAS 330819-78-8
1-(4-Aminophenyl)ethanone (5-allyl-6-methyl-2-phenyl-4-pyrimidinyl)hydrazone
CAS 330819-78-8C22H23N5
4-Methoxybenzaldehyde (5-allyl-6-methyl-2-phenyl-4-pyrimidinyl)hydrazone chemical structure, C22H22N4O, CAS 330998-10-2
4-Methoxybenzaldehyde (5-allyl-6-methyl-2-phenyl-4-pyrimidinyl)hydrazone
CAS 330998-10-2C22H22N4O
4-Bromobenzaldehyde (5-allyl-6-methyl-2-phenyl-4-pyrimidinyl)hydrazone chemical structure, C21H19BrN4, CAS 352660-89-0
4-Bromobenzaldehyde (5-allyl-6-methyl-2-phenyl-4-pyrimidinyl)hydrazone
CAS 352660-89-0C21H19BrN4
2-[4-[[(E)-Benzylideneamino]-methylamino]-6-methylpyrimidin-2-yl]phenol chemical structure, C19H18N4O, CAS 5256-63-3
2-[4-[[(E)-Benzylideneamino]-methylamino]-6-methylpyrimidin-2-yl]phenol
CAS 5256-63-3C19H18N4O
(E)-2-(4-(2-(2-Hydroxybenzylidene)hydrazinyl)-6-methylpyrimidin-2-yl)phenol chemical structure, C18H16N4O2, CAS 1391922-11-4
(E)-2-(4-(2-(2-Hydroxybenzylidene)hydrazinyl)-6-methylpyrimidin-2-yl)phenol
CAS 1391922-11-4C18H16N4O2
(E)-2-(4-(2-(4-Bromobenzylidene)hydrazinyl)-6-methylpyrimidin-2-yl)phenol chemical structure, C18H15BrN4O, CAS 330981-88-9
(E)-2-(4-(2-(4-Bromobenzylidene)hydrazinyl)-6-methylpyrimidin-2-yl)phenol
CAS 330981-88-9C18H15BrN4O
(E)-2-(4-(2-(2,4-Dimethoxybenzylidene)hydrazinyl)-6-methylpyrimidin-2-yl)phenol chemical structure, C20H20N4O3, CAS 330981-90-3
(E)-2-(4-(2-(2,4-Dimethoxybenzylidene)hydrazinyl)-6-methylpyrimidin-2-yl)phenol
CAS 330981-90-3C20H20N4O3
3,4-Dimethoxybenzaldehyde [2-(3,5-dibromo-2-hydroxyphenyl)-6-methyl-4-pyrimidinyl]hydrazone chemical structure, C20H18Br2N4O3, CAS 330993-81-2
3,4-Dimethoxybenzaldehyde [2-(3,5-dibromo-2-hydroxyphenyl)-6-methyl-4-pyrimidinyl]hydrazone
CAS 330993-81-2C20H18Br2N4O3
2-(4-{(2E)-2-[1-(2-Hydroxyphenyl)ethylidene]hydrazinyl}-6-methylpyrimidin-2-yl)phenol chemical structure, C19H18N4O2, CAS 300837-92-7
2-(4-{(2E)-2-[1-(2-Hydroxyphenyl)ethylidene]hydrazinyl}-6-methylpyrimidin-2-yl)phenol
CAS 300837-92-7C19H18N4O2