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Murcko scaffold

Ring system with 4 rings and 24 atoms

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
24
Chemicals
9
With full pages
1
Scaffold SMILES

C1=CC(c2ccccc2)c2cc(C=Nc3ccccc3)ccc2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C1=CC(c2ccccc2)c2cc(C=Nc3ccccc3)ccc2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

2-Amino-6-{[(3-butoxyphenyl)imino]methyl}-7-hydroxy-4-phenyl-4H-chromene-3-carbonitrile chemical structure, C27H25N3O3, CAS 352336-28-8
2-Amino-6-{[(3-butoxyphenyl)imino]methyl}-7-hydroxy-4-phenyl-4H-chromene-3-carbonitrile
CAS 352336-28-8C27H25N3O3
2-Amino-6-{(E)-[(4-bromophenyl)imino]methyl}-7-hydroxy-4-phenyl-4H-chromene-3-carbonitrile chemical structure, C23H16BrN3O2, CAS 368841-27-4
2-Amino-6-{(E)-[(4-bromophenyl)imino]methyl}-7-hydroxy-4-phenyl-4H-chromene-3-carbonitrile
CAS 368841-27-4C23H16BrN3O2
2-Amino-6-[(4-methoxyanilino)methylidene]-7-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile chemical structure, C24H19N3O3, CAS 304875-53-4
2-Amino-6-[(4-methoxyanilino)methylidene]-7-oxo-4-phenyl-4H-1-benzopyran-3-carbonitrile
CAS 304875-53-4C24H19N3O3
2-Amino-6-(((2,4-dimethylphenyl)imino)methyl)-4-phenyl-4H-chromene-3-carbonitrile chemical structure, C25H21N3O, CAS 370872-40-5
2-Amino-6-(((2,4-dimethylphenyl)imino)methyl)-4-phenyl-4H-chromene-3-carbonitrile
CAS 370872-40-5C25H21N3O
2-Amino-6-{(E)-[(3-methoxyphenyl)imino]methyl}-4-phenyl-4H-chromene-3-carbonitrile chemical structure, C24H19N3O2, CAS 300588-22-1
2-Amino-6-{(E)-[(3-methoxyphenyl)imino]methyl}-4-phenyl-4H-chromene-3-carbonitrile
CAS 300588-22-1C24H19N3O2
2-Amino-4-(4-bromophenyl)-6-[(E)-[(4-bromophenyl)imino]methyl]-7-hydroxy-4H-chromene-3-carbonitrile chemical structure, C23H15Br2N3O2, CAS 339191-33-2
2-Amino-4-(4-bromophenyl)-6-[(E)-[(4-bromophenyl)imino]methyl]-7-hydroxy-4H-chromene-3-carbonitrile
CAS 339191-33-2C23H15Br2N3O2
2-Amino-4-(4-bromophenyl)-7-hydroxy-6-[(E)-(phenylimino)methyl]-4H-chromene-3-carbonitrile chemical structure, C23H16BrN3O2, CAS 370075-07-3
2-Amino-4-(4-bromophenyl)-7-hydroxy-6-[(E)-(phenylimino)methyl]-4H-chromene-3-carbonitrile
CAS 370075-07-3C23H16BrN3O2
Ethyl 4-{[(E)-(2-amino-3-cyano-7-hydroxy-4-phenyl-4H-chromen-6-yl)methylidene]amino}benzoate chemical structure, C26H21N3O4, CAS 300393-97-9
Ethyl 4-{[(E)-(2-amino-3-cyano-7-hydroxy-4-phenyl-4H-chromen-6-yl)methylidene]amino}benzoate
CAS 300393-97-9C26H21N3O4
2-Amino-4-(4-bromophenyl)-6-{[(2,4-dimethylphenyl)imino]methyl}-7-hydroxy-4H-chromene-3-carbonitrile chemical structure, C25H20BrN3O2, CAS 352338-36-4
2-Amino-4-(4-bromophenyl)-6-{[(2,4-dimethylphenyl)imino]methyl}-7-hydroxy-4H-chromene-3-carbonitrile
CAS 352338-36-4C25H20BrN3O2