Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 23 atoms

21 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 23
Chemicals: 21
With full pages: 10

Scaffold SMILES

O=C(Nc1ccccc1)c1cc2cc3c(nc2s1)CCCCC3

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(Nc1ccccc1)c1cc2cc3c(nc2s1)CCCCC3

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 21 of 21 chemicals

3-Amino-N-phenyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C19H19N3OS, CAS 298219-02-0

3-Amino-N-phenyl-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 298219-02-0C₁₉H₁₉N₃OS

3-Amino-N-[4-(trifluoromethoxy)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H18F3N3O2S, CAS 445382-70-7

3-Amino-N-[4-(trifluoromethoxy)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 445382-70-7C₂₀H₁₈F₃N₃O₂S

3-Amino-N-[2-(trifluoromethoxy)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H18F3N3O2S, CAS 489462-22-8

3-Amino-N-[2-(trifluoromethoxy)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 489462-22-8C₂₀H₁₈F₃N₃O₂S

3-Amino-N-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide chemical structure, C19H18FN3OS, CAS 420835-61-6

3-Amino-N-(4-fluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide

CAS 420835-61-6C₁₉H₁₈FN₃OS

3-Amino-N-[2-(trifluoromethyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H18F3N3OS, CAS 387831-27-8

3-Amino-N-[2-(trifluoromethyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 387831-27-8C₂₀H₁₈F₃N₃OS

3-Amino-N-(3-cyanophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C21H17F3N4OS, CAS 626228-78-2

3-Amino-N-(3-cyanophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 626228-78-2C₂₁H₁₇F₃N₄OS

3-Amino-N-(2,4-difluorophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H16F5N3OS, CAS 626227-43-8

3-Amino-N-(2,4-difluorophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 626227-43-8C₂₀H₁₆F₅N₃OS

3-Amino-N-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H16ClF4N3OS, CAS 626227-58-5

3-Amino-N-(3-chloro-4-fluorophenyl)-4-(trifluoromethyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 626227-58-5C₂₀H₁₆ClF₄N₃OS

3-Amino-N-[4-(methylsulfanyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H21N3OS2, CAS 665000-93-1

3-Amino-N-[4-(methylsulfanyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 665000-93-1C₂₀H₂₁N₃OS₂

3-Amino-N-(3,4-dichlorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide chemical structure, C19H17Cl2N3OS, CAS 441718-29-2

3-Amino-N-(3,4-dichlorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide

CAS 441718-29-2C₁₉H₁₇Cl₂N₃OS

3-Amino-N-[2-chloro-5-(trifluoromethyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide chemical structure, C20H17ClF3N3OS, CAS 400864-42-8

3-Amino-N-[2-chloro-5-(trifluoromethyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide

CAS 400864-42-8C₂₀H₁₇ClF₃N₃OS

3-Amino-N-(4-methylphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide chemical structure, C20H21N3OS, CAS 354119-22-5

3-Amino-N-(4-methylphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide

CAS 354119-22-5C₂₀H₂₁N₃OS

3-Amino-N-(2,3-dimethylphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide chemical structure, C21H23N3OS, CAS 354119-24-7

3-Amino-N-(2,3-dimethylphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide

CAS 354119-24-7C₂₁H₂₃N₃OS

3-Amino-N-(3-methylphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide chemical structure, C20H21N3OS, CAS 428483-62-9

3-Amino-N-(3-methylphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide

CAS 428483-62-9C₂₀H₂₁N₃OS

3-Amino-N-(2-fluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide chemical structure, C19H18FN3OS, CAS 354119-25-8

3-Amino-N-(2-fluorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[B]thieno[3,2-E]pyridine-2-carboxamide

CAS 354119-25-8C₁₉H₁₈FN₃OS

3-Amino-N-(2,6-dichlorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C19H17Cl2N3OS, CAS 387831-20-1

3-Amino-N-(2,6-dichlorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 387831-20-1C₁₉H₁₇Cl₂N₃OS

3-Amino-N-[3-(trifluoromethyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H18F3N3OS, CAS 313379-74-7

3-Amino-N-[3-(trifluoromethyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 313379-74-7C₂₀H₁₈F₃N₃OS

3-Amino-N-(3-butoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C23H27N3O2S, CAS 336180-82-6

3-Amino-N-(3-butoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 336180-82-6C₂₃H₂₇N₃O₂S

3-Amino-N-[4-(aminosulfonyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C19H20N4O3S2, CAS 354119-23-6

3-Amino-N-[4-(aminosulfonyl)phenyl]-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 354119-23-6C₁₉H₂₀N₄O₃S₂

3-Amino-N-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide chemical structure, C19H18ClN3OS, CAS 428445-94-7

3-Amino-N-(4-chlorophenyl)-6,7,8,9-tetrahydro-5H-cyclohepta(B)thieno(3,2-E)pyridine-2-carboxamide

CAS 428445-94-7C₁₉H₁₈ClN₃OS

3-Amino-N-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide chemical structure, C20H21N3O2S, CAS 425682-99-1

3-Amino-N-(4-methoxyphenyl)-6,7,8,9-tetrahydro-5H-cyclohepta[b]thieno[3,2-e]pyridine-2-carboxamide

CAS 425682-99-1C₂₀H₂₁N₃O₂S