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Murcko scaffold

Ring system with 3 rings and 28 atoms

40 chemicals on CompoundList share this ring system.

Rings: 3
Scaffold atoms: 28
Chemicals: 40
With full pages: 2

Scaffold SMILES

O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)NCc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CN(Cc1ccccc1)S(=O)(=O)c1ccccc1)NCc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

N-[(4-Methylphenyl)methyl]-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C25H28N2O3S, CAS 433238-63-2

N-[(4-Methylphenyl)methyl]-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide

CAS 433238-63-2C₂₅H₂₈N₂O₃S

N-(2-Chlorobenzyl)-2-[[(4-chlorophenyl)sulfonyl](3-methylbenzyl)amino]acetamide chemical structure, C23H22Cl2N2O3S, CAS 666821-34-7

N-(2-Chlorobenzyl)-2-[[(4-chlorophenyl)sulfonyl](3-methylbenzyl)amino]acetamide

CAS 666821-34-7C₂₃H₂₂Cl₂N₂O₃S

2-[Benzenesulfonyl(benzyl)amino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C23H24N2O4S, CAS 331426-58-5

2-[Benzenesulfonyl(benzyl)amino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 331426-58-5C₂₃H₂₄N₂O₄S

2-[Benzenesulfonyl(benzyl)amino]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C23H24N2O3S, CAS 332898-77-8

2-[Benzenesulfonyl(benzyl)amino]-N-[(4-methylphenyl)methyl]acetamide

CAS 332898-77-8C₂₃H₂₄N₂O₃S

N-Benzyl-2-[(3,4-dichlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-methylacetamide chemical structure, C24H24Cl2N2O3S, CAS 433236-12-5

N-Benzyl-2-[(3,4-dichlorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-methylacetamide

CAS 433236-12-5C₂₄H₂₄Cl₂N₂O₃S

2-[Benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C23H23ClN2O3S, CAS 428824-74-2

2-[Benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(4-methylphenyl)methyl]acetamide

CAS 428824-74-2C₂₃H₂₃ClN₂O₃S

2-[Benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(2-chlorophenyl)methyl]acetamide chemical structure, C22H20Cl2N2O3S, CAS 433239-50-0

2-[Benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(2-chlorophenyl)methyl]acetamide

CAS 433239-50-0C₂₂H₂₀Cl₂N₂O₃S

N-[(2-Chlorophenyl)methyl]-2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C23H22Cl2N2O3S, CAS 592467-68-0

N-[(2-Chlorophenyl)methyl]-2-[(4-chlorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide

CAS 592467-68-0C₂₃H₂₂Cl₂N₂O₃S

2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-[(2-chlorophenyl)methyl]acetamide chemical structure, C22H19Cl3N2O3S, CAS 432526-10-8

2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-[(2-chlorophenyl)methyl]acetamide

CAS 432526-10-8C₂₂H₁₉Cl₃N₂O₃S

2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-[(4-chlorophenyl)methyl]acetamide chemical structure, C22H19Cl3N2O3S, CAS 431056-40-5

2-[Benzyl-(2,5-dichlorophenyl)sulfonylamino]-N-[(4-chlorophenyl)methyl]acetamide

CAS 431056-40-5C₂₂H₁₉Cl₃N₂O₃S

2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C23H23BrN2O4S, CAS 440098-13-5

2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 440098-13-5C₂₃H₂₃BrN₂O₄S

N-Benzyl-2-[(4-chlorophenyl)sulfonyl-[(4-fluorophenyl)methyl]amino]-N-methylacetamide chemical structure, C23H22ClFN2O3S, CAS 592467-23-7

N-Benzyl-2-[(4-chlorophenyl)sulfonyl-[(4-fluorophenyl)methyl]amino]-N-methylacetamide

CAS 592467-23-7C₂₃H₂₂ClFN₂O₃S

N-Benzyl-2-[(4-chlorophenyl)sulfonyl-[(4-fluorophenyl)methyl]amino]acetamide chemical structure, C22H20ClFN2O3S, CAS 433251-11-7

N-Benzyl-2-[(4-chlorophenyl)sulfonyl-[(4-fluorophenyl)methyl]amino]acetamide

CAS 433251-11-7C₂₂H₂₀ClFN₂O₃S

2-[(4-Chlorophenyl)sulfonyl-[(4-fluorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C23H22ClFN2O4S, CAS 433254-34-3

2-[(4-Chlorophenyl)sulfonyl-[(4-fluorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 433254-34-3C₂₃H₂₂ClFN₂O₄S

N-Benzyl-2-[(2-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-methylacetamide chemical structure, C24H25FN2O3S, CAS 690669-75-1

N-Benzyl-2-[(2-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-methylacetamide

CAS 690669-75-1C₂₄H₂₅FN₂O₃S

2-[(2-Chloro-6-fluorophenyl)methyl-(4-chlorophenyl)sulfonylamino]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C23H21Cl2FN2O3S, CAS 593256-29-2

2-[(2-Chloro-6-fluorophenyl)methyl-(4-chlorophenyl)sulfonylamino]-N-[(4-methylphenyl)methyl]acetamide

CAS 593256-29-2C₂₃H₂₁Cl₂FN₂O₃S

2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-[(4-methylphenyl)methyl]acetamide chemical structure, C23H23BrN2O3S, CAS 432010-65-6

2-[Benzenesulfonyl-[(4-bromophenyl)methyl]amino]-N-[(4-methylphenyl)methyl]acetamide

CAS 432010-65-6C₂₃H₂₃BrN₂O₃S

2-[(2-Fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C24H25FN2O4S, CAS 690671-82-0

2-[(2-Fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 690671-82-0C₂₄H₂₅FN₂O₄S

2-[(2-Chloro-6-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C24H24ClFN2O4S, CAS 499112-97-9

2-[(2-Chloro-6-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 499112-97-9C₂₄H₂₄ClFN₂O₄S

N-[(4-Methoxyphenyl)methyl]-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C25H28N2O4S, CAS 690674-02-3

N-[(4-Methoxyphenyl)methyl]-2-[(4-methylphenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide

CAS 690674-02-3C₂₅H₂₈N₂O₄S

N-[(2-Chlorophenyl)methyl]-2-[(4-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide chemical structure, C23H22ClFN2O3S, CAS 593257-15-9

N-[(2-Chlorophenyl)methyl]-2-[(4-fluorophenyl)methyl-(4-methylphenyl)sulfonylamino]acetamide

CAS 593257-15-9C₂₃H₂₂ClFN₂O₃S

2-[(4-Chlorophenyl)sulfonyl-[(2-fluorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C23H22ClFN2O4S, CAS 593255-66-4

2-[(4-Chlorophenyl)sulfonyl-[(2-fluorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 593255-66-4C₂₃H₂₂ClFN₂O₄S

N-Benzyl-2-[benzyl-(4-bromophenyl)sulfonylamino]-N-methylacetamide chemical structure, C23H23BrN2O3S, CAS 522661-97-8

N-Benzyl-2-[benzyl-(4-bromophenyl)sulfonylamino]-N-methylacetamide

CAS 522661-97-8C₂₃H₂₃BrN₂O₃S

2-[Benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide chemical structure, C23H23ClN2O4S, CAS 593243-55-1

2-[Benzenesulfonyl-[(4-chlorophenyl)methyl]amino]-N-[(4-methoxyphenyl)methyl]acetamide

CAS 593243-55-1C₂₃H₂₃ClN₂O₄S