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Murcko scaffold

2-Benzamido-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide scaffold

26 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
26
With full pages
6
Scaffold SMILES

O=C(Nc1sc2c(c1C(=O)Nc1ccccc1)CCC2)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Benzamido-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide page
Murcko scaffold O=C(Nc1sc2c(c1C(=O)Nc1ccccc1)CCC2)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-[(3-Methylbenzoyl)amino]-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H20N2O2S, CAS 329068-73-7
2-[(3-Methylbenzoyl)amino]-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329068-73-7C22H20N2O2S
2-[(2-Chlorobenzoyl)amino]-N-(4-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H21ClN2O3S, CAS 328286-15-3
2-[(2-Chlorobenzoyl)amino]-N-(4-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 328286-15-3C23H21ClN2O3S
2-[(2-Chlorobenzoyl)amino]-N-(4-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H19ClN2O2S, CAS 329067-08-5
2-[(2-Chlorobenzoyl)amino]-N-(4-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329067-08-5C22H19ClN2O2S
2-[(4-Methylbenzoyl)amino]-N-(4-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H22N2O2S, CAS 329066-78-6
2-[(4-Methylbenzoyl)amino]-N-(4-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329066-78-6C23H22N2O2S
N-(4-Ethoxyphenyl)-2-[(4-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C24H24N2O3S, CAS 329067-15-4
N-(4-Ethoxyphenyl)-2-[(4-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329067-15-4C24H24N2O3S
2-Benzamido-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C21H18N2O2S, CAS 301322-20-3
2-Benzamido-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 301322-20-3C21H18N2O2S
N-(3-Methoxyphenyl)-2-[(2-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H22N2O3S, CAS 663217-72-9
N-(3-Methoxyphenyl)-2-[(2-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 663217-72-9C23H22N2O3S
2-(Benzoylamino)-N-(2-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H20N2O2S, CAS 328286-08-4
2-(Benzoylamino)-N-(2-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 328286-08-4C22H20N2O2S
2-Benzamido-N-(4-chlorophenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C21H17ClN2O2S, CAS 5586-84-5
2-Benzamido-N-(4-chlorophenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 5586-84-5C21H17ClN2O2S
2-Benzamido-N-(4-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H22N2O3S, CAS 329067-07-4
2-Benzamido-N-(4-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329067-07-4C23H22N2O3S
2-[(2-Chlorobenzoyl)amino]-N-(3-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H19ClN2O2S, CAS 329067-09-6
2-[(2-Chlorobenzoyl)amino]-N-(3-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329067-09-6C22H19ClN2O2S
2-[(2-Chlorobenzoyl)amino]-N-(2-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H19ClN2O2S, CAS 329067-10-9
2-[(2-Chlorobenzoyl)amino]-N-(2-methylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329067-10-9C22H19ClN2O2S
2-[(4-Nitrobenzoyl)amino]-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C21H17N3O4S, CAS 306285-39-2
2-[(4-Nitrobenzoyl)amino]-N-phenyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 306285-39-2C21H17N3O4S
N-(4-Ethoxyphenyl)-2-[(4-nitrobenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H21N3O5S, CAS 313397-48-7
N-(4-Ethoxyphenyl)-2-[(4-nitrobenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 313397-48-7C23H21N3O5S
N-(4-Methoxyphenyl)-2-[(4-nitrobenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H19N3O5S, CAS 329067-16-5
N-(4-Methoxyphenyl)-2-[(4-nitrobenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329067-16-5C22H19N3O5S
2-Benzamido-N-(2-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H20N2O3S, CAS 328278-69-9
2-Benzamido-N-(2-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 328278-69-9C22H20N2O3S
2-[(2-Fluorobenzoyl)amino]-N-(2-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C22H19FN2O3S, CAS 397852-76-5
2-[(2-Fluorobenzoyl)amino]-N-(2-methoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 397852-76-5C22H19FN2O3S
N-(2-Ethoxyphenyl)-2-[(4-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C24H24N2O3S, CAS 329068-93-1
N-(2-Ethoxyphenyl)-2-[(4-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329068-93-1C24H24N2O3S
2-[(2-Chlorobenzoyl)amino]-N-(2-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H21ClN2O3S, CAS 6079-30-7
2-[(2-Chlorobenzoyl)amino]-N-(2-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 6079-30-7C23H21ClN2O3S
N-(4-Ethoxyphenyl)-2-[(3-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C24H24N2O3S, CAS 397854-76-1
N-(4-Ethoxyphenyl)-2-[(3-methylbenzoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 397854-76-1C24H24N2O3S
2-[(2-Chlorobenzoyl)amino]-N-(4-chlorophenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C21H16Cl2N2O2S, CAS 5580-35-8
2-[(2-Chlorobenzoyl)amino]-N-(4-chlorophenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 5580-35-8C21H16Cl2N2O2S
2-Benzamido-N-(2-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H22N2O3S, CAS 329068-88-4
2-Benzamido-N-(2-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 329068-88-4C23H22N2O3S
2-[(2-Chlorobenzoyl)amino]-N-(2-ethylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H21ClN2O2S, CAS 389073-44-3
2-[(2-Chlorobenzoyl)amino]-N-(2-ethylphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 389073-44-3C23H21ClN2O2S
2-[(2-Bromobenzoyl)amino]-N-(2-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C23H21BrN2O3S, CAS 354531-40-1
2-[(2-Bromobenzoyl)amino]-N-(2-ethoxyphenyl)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 354531-40-1C23H21BrN2O3S