Murcko scaffold
Ring system with 5 rings and 33 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 33
- Chemicals
- 8
- With full pages
- 5
Scaffold SMILES
O=C(CCC1N=C2c3ccccc3N=C(SCc3ccccc3)N2C1=O)NCc1ccco1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
![3-{5-[(2-Chlorobenzyl)thio]-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-2-yl}-N-(2-furylmethyl)propanamide chemical structure, C25H21ClN4O3S, CAS 1028018-33-8](/s/QMFWYWDZCAZGFT-UHFFFAOYSA-N.svg)
3-{5-[(2-Chlorobenzyl)thio]-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-2-yl}-N-(2-furylmethyl)propanamide
CAS 1028018-33-8C25H21ClN4O3S
![3-{5-[(4-Chlorobenzyl)thio]-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-2-yl}-N-(2-furylmethyl)propanamide chemical structure, C25H21ClN4O3S, CAS 1028018-38-3](/s/SKAVCAKFTFEDJA-UHFFFAOYSA-N.svg)
3-{5-[(4-Chlorobenzyl)thio]-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-2-yl}-N-(2-furylmethyl)propanamide
CAS 1028018-38-3C25H21ClN4O3S
![N-[(Furan-2-yl)methyl]-3-(5-{[(4-methylphenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)propanamide chemical structure, C26H24N4O3S, CAS 1034909-86-8](/s/LTDJOUXXLQRJML-UHFFFAOYSA-N.svg)
N-[(Furan-2-yl)methyl]-3-(5-{[(4-methylphenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)propanamide
CAS 1034909-86-8C26H24N4O3S
![3-(5-{[(3-Chlorophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)-N-[(furan-2-yl)methyl]propanamide chemical structure, C25H21ClN4O3S, CAS 1035035-98-3](/s/WMGRMVKKNJXQDA-UHFFFAOYSA-N.svg)
3-(5-{[(3-Chlorophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)-N-[(furan-2-yl)methyl]propanamide
CAS 1035035-98-3C25H21ClN4O3S
![3-{5-[(4-Fluorobenzyl)thio]-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-2-yl}-N-(2-furylmethyl)propanamide chemical structure, C25H21FN4O3S, CAS 1028024-75-0](/s/LKENQCHADBQIHZ-UHFFFAOYSA-N.svg)
3-{5-[(4-Fluorobenzyl)thio]-3-oxo-2,3-dihydroimidazo[1,2-c]quinazolin-2-yl}-N-(2-furylmethyl)propanamide
CAS 1028024-75-0C25H21FN4O3S
![N-[(Furan-2-yl)methyl]-3-(5-{[(3-nitrophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)propanamide chemical structure, C25H21N5O5S, CAS 1028031-42-6](/s/PJPDLRSSWLICPA-UHFFFAOYSA-N.svg)
N-[(Furan-2-yl)methyl]-3-(5-{[(3-nitrophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)propanamide
CAS 1028031-42-6C25H21N5O5S
![3-(5-{[(3-Fluorophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)-N-[(furan-2-yl)methyl]propanamide chemical structure, C25H21FN4O3S, CAS 1037824-50-2](/s/HQKYKZSNRKTSJO-UHFFFAOYSA-N.svg)
3-(5-{[(3-Fluorophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)-N-[(furan-2-yl)methyl]propanamide
CAS 1037824-50-2C25H21FN4O3S
![3-(5-{[(2-Fluorophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)-N-[(furan-2-yl)methyl]propanamide chemical structure, C25H21FN4O3S, CAS 1038400-75-7](/s/VVQUWBYQZKXZPS-UHFFFAOYSA-N.svg)
3-(5-{[(2-Fluorophenyl)methyl]sulfanyl}-3-oxo-2H,3H-imidazo[1,2-c]quinazolin-2-yl)-N-[(furan-2-yl)methyl]propanamide
CAS 1038400-75-7C25H21FN4O3S