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Murcko scaffold

Ring system with 4 rings and 18 atoms

5 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
18
Chemicals
5
With full pages
2
Scaffold SMILES

c1csc(C2Nc3ccccc3C3OCCC23)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1csc(C2Nc3ccccc3C3OCCC23)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

1-(7,9-Dimethyl-4-thiophen-2-yl-3,3a,4,9b-tetrahydro-2H-furo[3,2-c]quinolin-5-yl)ethanone chemical structure, C19H21NO2S, CAS 1005110-51-9
1-(7,9-Dimethyl-4-thiophen-2-yl-3,3a,4,9b-tetrahydro-2H-furo[3,2-c]quinolin-5-yl)ethanone
CAS 1005110-51-9C19H21NO2S
8-Methyl-4-thiophen-2-yl-2,3,3a,4,5,9b-hexahydro-furo[3,2-c]quinoline chemical structure, C16H17NOS, CAS 937169-58-9
8-Methyl-4-thiophen-2-yl-2,3,3a,4,5,9b-hexahydro-furo[3,2-c]quinoline
CAS 937169-58-9C16H17NOS
(3aS,4S,9bS)-8-Bromo-4-thiophen-2-yl-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline chemical structure, C15H14BrNOS, CAS 957270-64-3
(3aS,4S,9bS)-8-Bromo-4-thiophen-2-yl-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline
CAS 957270-64-3C15H14BrNOS
(3aR,4R,9bR)-8-Methyl-4-thiophen-2-yl-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline chemical structure, C16H17NOS, CAS 1212073-23-8
(3aR,4R,9bR)-8-Methyl-4-thiophen-2-yl-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline
CAS 1212073-23-8C16H17NOS
7,9-Dimethyl-4-(2-thienyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline chemical structure, C17H19NOS, CAS 957496-53-6
7,9-Dimethyl-4-(2-thienyl)-2,3,3a,4,5,9b-hexahydrofuro[3,2-c]quinoline
CAS 957496-53-6C17H19NOS