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Murcko scaffold

Ring system with 5 rings and 28 atoms

8 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
28
Chemicals
8
With full pages
3
Scaffold SMILES

c1ccc(Cc2nc(-c3ccccc3)cn3cc(Cc4ccco4)nc23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(Cc2nc(-c3ccccc3)cn3cc(Cc4ccco4)nc23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

8-Benzyl-2-[(furan-2-yl)methyl]-6-phenyl-3H,7H-imidazo[1,2-a]pyrazin-3-one chemical structure, C24H19N3O2, CAS 1374040-24-0
8-Benzyl-2-[(furan-2-yl)methyl]-6-phenyl-3H,7H-imidazo[1,2-a]pyrazin-3-one
CAS 1374040-24-0C24H19N3O2
2-(2-Furanylmethyl)-6-(4-hydroxyphenyl)-8-(phenylmethyl)imidazo[1,2-a]pyrazin-3(7H)-one chemical structure, C24H19N3O3, CAS 1374302-53-0
2-(2-Furanylmethyl)-6-(4-hydroxyphenyl)-8-(phenylmethyl)imidazo[1,2-a]pyrazin-3(7H)-one
CAS 1374302-53-0C24H19N3O3
Hydrofurimazine chemical structure, C24H19N3O3, CAS 2179052-10-7
Hydrofurimazine
CAS 2179052-10-7C24H19N3O3
6-(3-Amino-2-fluorophenyl)-8-((2-fluorophenyl)methyl)-2-((furan-2-yl)methyl)-3H,7H-imidazo(1,2-a)pyrazin-3-one chemical structure, C24H18F2N4O2, CAS 2412089-96-2
6-(3-Amino-2-fluorophenyl)-8-((2-fluorophenyl)methyl)-2-((furan-2-yl)methyl)-3H,7H-imidazo(1,2-a)pyrazin-3-one
CAS 2412089-96-2C24H18F2N4O2
NanoLuc substrate 1 chemical structure, C24H18FN3O3, CAS 2412089-75-7
NanoLuc substrate 1
CAS 2412089-75-7C24H18FN3O3
NanoLuc substrate 2 chemical structure, C24H19FN4O2, CAS 2412089-80-4
NanoLuc substrate 2
CAS 2412089-80-4C24H19FN4O2
6-(2-Fluoro-3-nitrophenyl)-8-(2-fluorobenzyl)-2-(furan-2-ylmethyl)imidazo[1,2-A]pyrazin-3(7H)-one chemical structure, C24H16F2N4O4, CAS 2412091-25-7
6-(2-Fluoro-3-nitrophenyl)-8-(2-fluorobenzyl)-2-(furan-2-ylmethyl)imidazo[1,2-A]pyrazin-3(7H)-one
CAS 2412091-25-7C24H16F2N4O4
Cephalofurimazine chemical structure, C24H17F2N3O2, CAS 3033659-13-8
Cephalofurimazine
CAS 3033659-13-8C24H17F2N3O2