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Murcko scaffold

Ring system with 3 rings and 22 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
22
Chemicals
8
With full pages
4
Scaffold SMILES

O=C(CNC(=O)C1CCCN1)Nc1ccc2ccccc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNC(=O)C1CCCN1)Nc1ccc2ccccc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Glycyl-prolyl-methionyl-2-naphthylamide chemical structure, C22H28N4O3S, CAS 95574-36-0
Glycyl-prolyl-methionyl-2-naphthylamide
CAS 95574-36-0C22H28N4O3S
Glycyl-prolyl-leucyl-2-naphthylamide chemical structure, C23H30N4O3, CAS 95574-38-2
Glycyl-prolyl-leucyl-2-naphthylamide
CAS 95574-38-2C23H30N4O3
N-[5-(Diaminomethylideneamino)-1-[(4-methoxynaphthalen-2-yl)amino]-1-oxopentan-2-yl]pyrrolidine-2-carboxamide chemical structure, C22H30N6O3, CAS 42761-75-1
N-[5-(Diaminomethylideneamino)-1-[(4-methoxynaphthalen-2-yl)amino]-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
CAS 42761-75-1C22H30N6O3
L-Prolyl-N-2-naphthalenyl-L-argininamide chemical structure, C21H28N6O2, CAS 138914-35-9
L-Prolyl-N-2-naphthalenyl-L-argininamide
CAS 138914-35-9C21H28N6O2
N-Acetylalanylalanylprolyl-N-naphthalen-2-ylalaninamide chemical structure, C26H33N5O5, CAS 102029-65-2
N-Acetylalanylalanylprolyl-N-naphthalen-2-ylalaninamide
CAS 102029-65-2C26H33N5O5
H-Gly-Pro-Leu-bNA.HCl chemical structure, C23H31ClN4O3
H-Gly-Pro-Leu-bNA.HCl
C23H31ClN4O3
H-Gly-Pro-Leu-beta-na hydrochloride chemical structure, C23H31ClN4O3, CAS 100929-83-7
H-Gly-Pro-Leu-beta-na hydrochloride
CAS 100929-83-7C23H31ClN4O3
H-Pro-Arg-bNA HCl chemical structure, C21H29ClN6O2, CAS 201998-83-6
H-Pro-Arg-bNA HCl
CAS 201998-83-6C21H29ClN6O2