CompoundList
Sign in
Murcko scaffold

Ring system with 4 rings and 19 atoms

16 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
19
Chemicals
16
With full pages
3
Scaffold SMILES

c1ccc(-c2nnc3sc(-c4cccs4)nn23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nnc3sc(-c4cccs4)nn23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

3-(3,4-Dimethoxyphenyl)-6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C15H12N4O2S2, CAS 129081-89-6
3-(3,4-Dimethoxyphenyl)-6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 129081-89-6C15H12N4O2S2
6-Thiophen-2-yl-3-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C16H14N4O3S2, CAS 825605-62-7
6-Thiophen-2-yl-3-(3,4,5-trimethoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 825605-62-7C16H14N4O3S2
3-(4-Methylphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C14H10N4S2, CAS 724429-15-6
3-(4-Methylphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 724429-15-6C14H10N4S2
3-(3-Fluorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7FN4S2, CAS 724436-16-2
3-(3-Fluorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 724436-16-2C13H7FN4S2
3-(4-Fluorophenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7FN4S2, CAS 353288-21-8
3-(4-Fluorophenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 353288-21-8C13H7FN4S2
3-(3-Chlorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7ClN4S2, CAS 791824-42-5
3-(3-Chlorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 791824-42-5C13H7ClN4S2
3-(4-Chlorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7ClN4S2, CAS 537016-78-7
3-(4-Chlorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 537016-78-7C13H7ClN4S2
3-(3-Methylphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C14H10N4S2, CAS 794550-35-9
3-(3-Methylphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 794550-35-9C14H10N4S2
3-(2-Methylphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C14H10N4S2, CAS 578750-08-0
3-(2-Methylphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 578750-08-0C14H10N4S2
3-(4-Methoxyphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C14H10N4OS2, CAS 577700-42-6
3-(4-Methoxyphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 577700-42-6C14H10N4OS2
3-(2-Methoxyphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C14H10N4OS2, CAS 579442-28-7
3-(2-Methoxyphenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 579442-28-7C14H10N4OS2
3-(2-Bromophenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7BrN4S2, CAS 537016-80-1
3-(2-Bromophenyl)-6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 537016-80-1C13H7BrN4S2
3-(4-Bromophenyl)-6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7BrN4S2, CAS 537016-73-2
3-(4-Bromophenyl)-6-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 537016-73-2C13H7BrN4S2
3-(2-Chlorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C13H7ClN4S2, CAS 577697-51-9
3-(2-Chlorophenyl)-6-(2-thienyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 577697-51-9C13H7ClN4S2
N,N-Dimethyl-4-(6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)aniline chemical structure, C15H13N5S2, CAS 878431-28-8
N,N-Dimethyl-4-(6-thiophen-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl)aniline
CAS 878431-28-8C15H13N5S2
3-(2-Chlorophenyl)-6-(3-methylthiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole chemical structure, C14H9ClN4S2, CAS 1010882-54-8
3-(2-Chlorophenyl)-6-(3-methylthiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
CAS 1010882-54-8C14H9ClN4S2