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Murcko scaffold

Ring system with 3 rings and 19 atoms

14 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
19
Chemicals
14
With full pages
10
Scaffold SMILES

O=C(NC1CCSc2ccccc21)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCSc2ccccc21)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

3-(Difluoromethoxy)-N-(3,4-dihydro-2H-thiochromen-4-yl)benzamide chemical structure, C17H15F2NO2S, CAS 871906-42-2
3-(Difluoromethoxy)-N-(3,4-dihydro-2H-thiochromen-4-yl)benzamide
CAS 871906-42-2C17H15F2NO2S
3-Chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)benzamide chemical structure, C16H14ClNOS, CAS 876907-65-2
3-Chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)benzamide
CAS 876907-65-2C16H14ClNOS
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3,5-dimethoxybenzamide chemical structure, C18H19NO3S, CAS 876907-67-4
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3,5-dimethoxybenzamide
CAS 876907-67-4C18H19NO3S
Methyl 4-(3,4-dihydro-2H-thiochromen-4-ylcarbamoyl)benzoate chemical structure, C18H17NO3S, CAS 877051-55-3
Methyl 4-(3,4-dihydro-2H-thiochromen-4-ylcarbamoyl)benzoate
CAS 877051-55-3C18H17NO3S
2-Chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)-6-fluorobenzamide chemical structure, C16H13ClFNOS, CAS 926744-37-8
2-Chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)-6-fluorobenzamide
CAS 926744-37-8C16H13ClFNOS
N-(3,4-Dihydro-2H-thiochromen-4-yl)-2,5-dimethoxybenzamide chemical structure, C18H19NO3S, CAS 878927-02-7
N-(3,4-Dihydro-2H-thiochromen-4-yl)-2,5-dimethoxybenzamide
CAS 878927-02-7C18H19NO3S
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3-fluoro-4-methoxybenzamide chemical structure, C17H16FNO2S, CAS 878919-85-8
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3-fluoro-4-methoxybenzamide
CAS 878919-85-8C17H16FNO2S
N-(3,4-Dihydro-2H-thiochromen-4-yl)-4-nitrobenzamide chemical structure, C16H14N2O3S, CAS 923850-98-0
N-(3,4-Dihydro-2H-thiochromen-4-yl)-4-nitrobenzamide
CAS 923850-98-0C16H14N2O3S
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3-sulfamoylbenzamide chemical structure, C16H16N2O3S2, CAS 924049-74-1
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3-sulfamoylbenzamide
CAS 924049-74-1C16H16N2O3S2
4-Chloro-N-(3,4-dihydro-2H-1-benzothiopyran-4-yl)-3-sulfamoylbenzamide chemical structure, C16H15ClN2O3S2, CAS 924371-05-1
4-Chloro-N-(3,4-dihydro-2H-1-benzothiopyran-4-yl)-3-sulfamoylbenzamide
CAS 924371-05-1C16H15ClN2O3S2
N-(3,4-Dihydro-2H-thiochromen-4-yl)-4-(methoxymethyl)benzamide chemical structure, C18H19NO2S, CAS 924721-24-4
N-(3,4-Dihydro-2H-thiochromen-4-yl)-4-(methoxymethyl)benzamide
CAS 924721-24-4C18H19NO2S
N-(3,4-Dihydro-2H-1-benzothiopyran-4-yl)-2-methoxybenzamide chemical structure, C17H17NO2S, CAS 923696-66-6
N-(3,4-Dihydro-2H-1-benzothiopyran-4-yl)-2-methoxybenzamide
CAS 923696-66-6C17H17NO2S
N-(3,4-Dihydro-2H-thiochromen-4-yl)-2-fluorobenzamide chemical structure, C16H14FNOS, CAS 1007729-17-0
N-(3,4-Dihydro-2H-thiochromen-4-yl)-2-fluorobenzamide
CAS 1007729-17-0C16H14FNOS
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3-nitrobenzamide chemical structure, C16H14N2O3S, CAS 1007777-90-3
N-(3,4-Dihydro-2H-thiochromen-4-yl)-3-nitrobenzamide
CAS 1007777-90-3C16H14N2O3S