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Murcko scaffold

7-Phenyl-1,6-naphthyridine scaffold

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
28
With full pages
4
Scaffold SMILES

c1ccc(-c2cc3ncccc3cn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 7-Phenyl-1,6-naphthyridine page
Murcko scaffold c1ccc(-c2cc3ncccc3cn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

N-{7-[4-(Dimethylamino)phenyl]-1,6-Naphthyridin-5-Yl}propane-1,3-Diamine chemical structure, C19H23N5, CAS 562050-39-9
N-{7-[4-(Dimethylamino)phenyl]-1,6-Naphthyridin-5-Yl}propane-1,3-Diamine
CAS 562050-39-9C19H23N5
7-[4-(Dimethylamino)phenyl]-n,n-dimethyl-1,6-naphthyridin-5-amine chemical structure, C18H20N4, CAS 562050-49-1
7-[4-(Dimethylamino)phenyl]-n,n-dimethyl-1,6-naphthyridin-5-amine
CAS 562050-49-1C18H20N4
N1-(7-(3-chlorophenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C17H17ClN4, CAS 562050-31-1
N1-(7-(3-chlorophenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-31-1C17H17ClN4
N1-(7-(4-isopropylphenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C20H24N4, CAS 562050-47-9
N1-(7-(4-isopropylphenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-47-9C20H24N4
N1-(7-(4-methoxyphenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C18H20N4O, CAS 562050-17-3
N1-(7-(4-methoxyphenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-17-3C18H20N4O
1-Amino-3-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-ylamino)propan-2-ol chemical structure, C19H23N5O, CAS 562050-60-6
1-Amino-3-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-ylamino)propan-2-ol
CAS 562050-60-6C19H23N5O
N1-[7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl]-1,5-pentanediamine chemical structure, C21H27N5, CAS 562050-51-5
N1-[7-[4-(dimethylamino)phenyl]-1,6-naphthyridin-5-yl]-1,5-pentanediamine
CAS 562050-51-5C21H27N5
7-[4-(Dimethylamino)phenyl]-N-methyl-1,6-naphthyridin-5-amine chemical structure, C17H18N4, CAS 562050-48-0
7-[4-(Dimethylamino)phenyl]-N-methyl-1,6-naphthyridin-5-amine
CAS 562050-48-0C17H18N4
N*1*-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-yl]-2,2-dimethyl-propane-1,3-diamine chemical structure, C21H27N5, CAS 562050-61-7
N*1*-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-yl]-2,2-dimethyl-propane-1,3-diamine
CAS 562050-61-7C21H27N5
N'-[7-(4-Bromophenyl)-1,6-naphthyridin-5-yl]propane-1,3-diamine chemical structure, C17H17BrN4, CAS 562050-44-6
N'-[7-(4-Bromophenyl)-1,6-naphthyridin-5-yl]propane-1,3-diamine
CAS 562050-44-6C17H17BrN4
N1-(7-phenyl-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C17H18N4, CAS 562050-25-3
N1-(7-phenyl-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-25-3C17H18N4
N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-yl)ethane-1,2-diamine chemical structure, C18H21N5, CAS 562050-20-8
N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-yl)ethane-1,2-diamine
CAS 562050-20-8C18H21N5
3-(7-(4-(Dimethylamino)phenyl)-1,6-naphthyridin-5-yloxy)propan-1-ol chemical structure, C19H21N3O2, CAS 562050-52-6
3-(7-(4-(Dimethylamino)phenyl)-1,6-naphthyridin-5-yloxy)propan-1-ol
CAS 562050-52-6C19H21N3O2
N1-(7-p-tolyl-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C18H20N4, CAS 562050-45-7
N1-(7-p-tolyl-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-45-7C18H20N4
N1-(7-(4-chlorophenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C17H17ClN4, CAS 562050-36-6
N1-(7-(4-chlorophenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-36-6C17H17ClN4
4-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-ylamino]-butan-1-ol chemical structure, C20H24N4O, CAS 562050-54-8
4-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-ylamino]-butan-1-ol
CAS 562050-54-8C20H24N4O
N*1*-[7-(4-Diethylamino-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine chemical structure, C21H27N5, CAS 562050-40-2
N*1*-[7-(4-Diethylamino-phenyl)-[1,6]naphthyridin-5-yl]-propane-1,3-diamine
CAS 562050-40-2C21H27N5
N1-[3-bromo-7-(4-methoxyphenyl)-1,6-naphthyridin-5-yl]-1,3-propanediamine chemical structure, C18H19BrN4O, CAS 562050-23-1
N1-[3-bromo-7-(4-methoxyphenyl)-1,6-naphthyridin-5-yl]-1,3-propanediamine
CAS 562050-23-1C18H19BrN4O
N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-yl)butane-1,4-diamine chemical structure, C20H25N5, CAS 562050-50-4
N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-yl)butane-1,4-diamine
CAS 562050-50-4C20H25N5
7-Phenyl-1,6-naphthyridine chemical structure, C14H10N2, CAS 222168-29-8
7-Phenyl-1,6-naphthyridine
CAS 222168-29-8C14H10N2
4-(5-(4-Aminobutoxy)-1,6-naphthyridin-7-yl)-N,N-dimethylaniline chemical structure, C20H24N4O, CAS 562050-53-7
4-(5-(4-Aminobutoxy)-1,6-naphthyridin-7-yl)-N,N-dimethylaniline
CAS 562050-53-7C20H24N4O
7-(4-Methoxyphenyl)-N-methyl-1,6-naphthyridin-5-amine chemical structure, C16H15N3O, CAS 562050-12-8
7-(4-Methoxyphenyl)-N-methyl-1,6-naphthyridin-5-amine
CAS 562050-12-8C16H15N3O
5-(3-Aminopropylamino)-2-trifluoromethyl-7-(4-methoxyphenyl)-[1,6]naphthyridine chemical structure, C19H19F3N4O, CAS 562050-22-0
5-(3-Aminopropylamino)-2-trifluoromethyl-7-(4-methoxyphenyl)-[1,6]naphthyridine
CAS 562050-22-0C19H19F3N4O
N1-(7-(4-((2-(dimethylamino)ethyl)(methyl)amino)phenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine chemical structure, C22H30N6, CAS 562050-42-4
N1-(7-(4-((2-(dimethylamino)ethyl)(methyl)amino)phenyl)-1,6-naphthyridin-5-yl)propane-1,3-diamine
CAS 562050-42-4C22H30N6