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Murcko scaffold

2-Phenyl-5,6,7,8-tetrahydroquinazoline scaffold

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
25
With full pages
6
Scaffold SMILES

c1ccc(-c2ncc3c(n2)CCCC3)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-5,6,7,8-tetrahydroquinazoline page
Murcko scaffold c1ccc(-c2ncc3c(n2)CCCC3)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)acetic acid chemical structure, C16H16N2O2S, CAS 632289-45-3
2-((2-Phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)thio)acetic acid
CAS 632289-45-3C16H16N2O2S
2-((2-(m-Tolyl)-5,6,7,8-tetrahydroquinazolin-4-yl)thio)acetic acid chemical structure, C17H18N2O2S, CAS 632289-50-0
2-((2-(m-Tolyl)-5,6,7,8-tetrahydroquinazolin-4-yl)thio)acetic acid
CAS 632289-50-0C17H18N2O2S
4-(Methylsulfanyl)-2-phenyl-5,6,7,8-tetrahydroquinazoline chemical structure, C15H16N2S, CAS 95695-64-0
4-(Methylsulfanyl)-2-phenyl-5,6,7,8-tetrahydroquinazoline
CAS 95695-64-0C15H16N2S
Methyl 2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]acetate chemical structure, C17H18N2O2S, CAS 107466-59-1
Methyl 2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]acetate
CAS 107466-59-1C17H18N2O2S
Quinazoline, 5,6,7,8-tetrahydro-4-methyl-2-phenyl- chemical structure, C15H16N2, CAS 142965-56-8
Quinazoline, 5,6,7,8-tetrahydro-4-methyl-2-phenyl-
CAS 142965-56-8C15H16N2
N,N-Dimethyl-2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]ethanamine chemical structure, C18H23N3S, CAS 847183-40-8
N,N-Dimethyl-2-[(2-phenyl-5,6,7,8-tetrahydroquinazolin-4-yl)sulfanyl]ethanamine
CAS 847183-40-8C18H23N3S
Methyl 2-{[2-(3-methylphenyl)-5,6,7,8-tetrahydroquinazolin-4-yl]sulfanyl}acetate chemical structure, C18H20N2O2S, CAS 694460-85-0
Methyl 2-{[2-(3-methylphenyl)-5,6,7,8-tetrahydroquinazolin-4-yl]sulfanyl}acetate
CAS 694460-85-0C18H20N2O2S
N,N-Dimethyl-2-(2-phenyl-5,6,7,8-tetrahydro-quinazolin-4-ylsulfanyl)-acetamide chemical structure, C18H21N3OS, CAS 780777-52-8
N,N-Dimethyl-2-(2-phenyl-5,6,7,8-tetrahydro-quinazolin-4-ylsulfanyl)-acetamide
CAS 780777-52-8C18H21N3OS
N,N-Dimethyl-2-(2-m-tolyl-5,6,7,8-tetrahydro-quinazolin-4-ylsulfanyl)-acetamide chemical structure, C19H23N3OS, CAS 799256-17-0
N,N-Dimethyl-2-(2-m-tolyl-5,6,7,8-tetrahydro-quinazolin-4-ylsulfanyl)-acetamide
CAS 799256-17-0C19H23N3OS
2-Phenyl-5,6,7,8-tetrahydroquinazoline chemical structure, C14H14N2, CAS 100869-87-2
2-Phenyl-5,6,7,8-tetrahydroquinazoline
CAS 100869-87-2C14H14N2
2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine chemical structure, C14H15N3, CAS 929973-44-4
2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine
CAS 929973-44-4C14H15N3
4-Chloro-2-phenyl-5,6,7,8-tetrahydroquinazoline chemical structure, C14H13ClN2, CAS 17709-79-4
4-Chloro-2-phenyl-5,6,7,8-tetrahydroquinazoline
CAS 17709-79-4C14H13ClN2
4-Chloro-2-(3-chlorophenyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C14H12Cl2N2, CAS 184109-90-8
4-Chloro-2-(3-chlorophenyl)-5,6,7,8-tetrahydroquinazoline
CAS 184109-90-8C14H12Cl2N2
2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine hydrochloride chemical structure, C14H16ClN3, CAS 1193387-22-2
2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine hydrochloride
CAS 1193387-22-2C14H16ClN3
2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine dihydrochloride chemical structure, C14H17Cl2N3, CAS 1193389-46-6
2-Phenyl-5,6,7,8-tetrahydroquinazolin-6-amine dihydrochloride
CAS 1193389-46-6C14H17Cl2N3
4-Chloro-2-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydroquinazoline chemical structure, C15H12ClF3N2, CAS 1303652-63-2
4-Chloro-2-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydroquinazoline
CAS 1303652-63-2C15H12ClF3N2
2-Phenyl-5,6,7,8-tetrahydroquinazolin-5-amine chemical structure, C14H15N3, CAS 927803-68-7
2-Phenyl-5,6,7,8-tetrahydroquinazolin-5-amine
CAS 927803-68-7C14H15N3
2-Phenyl-5-[(prop-2-yn-1-yl)oxy]-5,6,7,8-tetrahydroquinazoline chemical structure, C17H16N2O, CAS 140655-13-6
2-Phenyl-5-[(prop-2-yn-1-yl)oxy]-5,6,7,8-tetrahydroquinazoline
CAS 140655-13-6C17H16N2O
5-Quinazolinol,5,6,7,8-tetrahydro-2-phenyl- chemical structure, C14H14N2O, CAS 140655-02-3
5-Quinazolinol,5,6,7,8-tetrahydro-2-phenyl-
CAS 140655-02-3C14H14N2O
2-Phenyl-5,6,7,8-tetrahydroquinazoline hydrochloride chemical structure, C14H15ClN2, CAS 109126-56-9
2-Phenyl-5,6,7,8-tetrahydroquinazoline hydrochloride
CAS 109126-56-9C14H15ClN2
Ethyl 2-(3-bromophenyl)-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline-4-carboxylate chemical structure, C19H21BrN2O2, CAS 1660116-73-3
Ethyl 2-(3-bromophenyl)-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline-4-carboxylate
CAS 1660116-73-3C19H21BrN2O2
2-(3-Bromophenyl)-5,6,7,8-tetrahydro-4-quinazolinecarboxamide chemical structure, C15H14BrN3O, CAS 1660116-79-9
2-(3-Bromophenyl)-5,6,7,8-tetrahydro-4-quinazolinecarboxamide
CAS 1660116-79-9C15H14BrN3O
2-(3-Bromophenyl)-5,6,7,8-tetrahydro-4-quinazolinecarboxylic acid chemical structure, C15H13BrN2O2, CAS 1660116-77-7
2-(3-Bromophenyl)-5,6,7,8-tetrahydro-4-quinazolinecarboxylic acid
CAS 1660116-77-7C15H13BrN2O2
2-(4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazolin-2-yl)-phenol chemical structure, C15H15ClN2O, CAS 845548-14-3
2-(4-Chloro-7-methyl-5,6,7,8-tetrahydroquinazolin-2-yl)-phenol
CAS 845548-14-3C15H15ClN2O