Murcko scaffold
Ring system with 5 rings and 29 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 29
- Chemicals
- 8
- With full pages
- 1
Scaffold SMILES
O=C(CCc1cc2c(s1)-n1cnnc1CN=C2c1ccccc1)N1CCOCC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Apafant
CAS 105219-56-5C22H22ClN5O2S
Web 2105
CAS 105219-69-0C21H20ClN5O2S
Morpholine, 4-(3-(9-methyl-4-phenyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-2-yl)-1-oxopropyl)-
CAS 105219-70-3C22H23N5O2S
Morpholine, 4-(3-(9-bromo-4-(2-chlorophenyl)-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-2-yl)-1-oxopropyl)-
CAS 105241-81-4C21H19BrClN5O2S
Morpholine, 4-(3-(4-(2-chlorophenyl)-9-propoxy-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-2-yl)-1-oxopropyl)-
CAS 133714-99-5C24H26ClN5O3S
Morpholine, 4-(3-(9-(chloromethyl)-4-(2-chlorophenyl)-6H-thieno(3,2-f)(1,4)triazolo(4,3-a)(1,4)diazepin-2-yl)-1-oxopropyl)-
CAS 113825-87-9C22H21Cl2N5O2S
Morpholine, 4-(3-(9-(bromomethyl)-4-(2-chlorophenyl)-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-2-yl)-1-oxopropyl)-
CAS 113825-88-0C22H21BrClN5O2S
Apafant-d8
CAS 1185101-22-7C22H22ClN5O2S