Murcko scaffold
Ring system with 4 rings and 18 atoms
7 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 18
- Chemicals
- 7
- With full pages
- 3
Scaffold SMILES
c1ccc2cc(C3CCn4cncc43)ccc2c1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 7 of 7 chemicals
Orteronel
CAS 566939-85-3C18H17N3O2
![6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide chemical structure, C18H17N3O2, CAS 426219-18-3](/s/OZPFIJIOIVJZMN-UHFFFAOYSA-N.svg)
6-(7-Hydroxy-6,7-dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
CAS 426219-18-3C18H17N3O2
Orteronel, (R)-
CAS 752243-39-3C18H17N3O2
![6-(6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide chemical structure, C18H17N3O, CAS 426219-44-5](/s/KVDGTWKQXMEUBX-UHFFFAOYSA-N.svg)
6-(6,7-Dihydro-5H-pyrrolo[1,2-c]imidazol-7-yl)-N-methyl-2-naphthamide
CAS 426219-44-5C18H17N3O
TAK-700(salt)
CAS 426219-53-6C28H28N4O7
TAK-700(salt)
C28H28N4O7
TAK-700 salt
C28H28N4O7
Related scaffolds
Same ring framework with different atoms or bond orders
