Murcko scaffold
Ring system with 4 rings and 21 atoms
28 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 21
- Chemicals
- 28
- With full pages
- 4
Scaffold SMILES
c1ccc(-c2cnn3c(NC4CCCC4)ccnc23)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 28 of 28 chemicals
![N-Cyclopentyl-2-methyl-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26N4, CAS 896834-42-7](/s/HUROSOQXTDWWTB-UHFFFAOYSA-N.svg)
N-Cyclopentyl-2-methyl-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896834-42-7C21H26N4
![3-(4-Chlorophenyl)-N-cyclopentyl-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C18H19ClN4, CAS 896845-43-5](/s/IXMWDIRAWQZSJQ-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-N-cyclopentyl-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896845-43-5C18H19ClN4
![5-tert-Butyl-3-(4-chlorophenyl)-N-cyclopentylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H25ClN4, CAS 899396-99-7](/s/LUQXPSJVVZREJX-UHFFFAOYSA-N.svg)
5-tert-Butyl-3-(4-chlorophenyl)-N-cyclopentylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 899396-99-7C21H25ClN4
![5-tert-Butyl-N-cyclopentyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26N4, CAS 900272-80-2](/s/GGEMJORGFHBZQO-UHFFFAOYSA-N.svg)
5-tert-Butyl-N-cyclopentyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900272-80-2C21H26N4
![5-tert-Butyl-N-cyclopentyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H28N4, CAS 850731-59-8](/s/LGDYZWBQZIPNEQ-UHFFFAOYSA-N.svg)
5-tert-Butyl-N-cyclopentyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 850731-59-8C22H28N4
![N-Cyclopentyl-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H22N4, CAS 850746-57-5](/s/QVXSMTHKFBACMS-UHFFFAOYSA-N.svg)
N-Cyclopentyl-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 850746-57-5C19H22N4
![N-Cyclopentyl-2-methyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26N4, CAS 896601-75-5](/s/WUOWNTFXLCUMNU-UHFFFAOYSA-N.svg)
N-Cyclopentyl-2-methyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896601-75-5C21H26N4
![3-(4-Chlorophenyl)-N-cyclopentyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H21ClN4, CAS 877778-35-3](/s/NKDCBQBFIMIMPF-UHFFFAOYSA-N.svg)
3-(4-Chlorophenyl)-N-cyclopentyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877778-35-3C19H21ClN4
![5-tert-Butyl-3-(4-chlorophenyl)-N-cyclopentyl-2-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H27ClN4, CAS 877646-95-2](/s/NAFOTAAJQTUKRM-UHFFFAOYSA-N.svg)
5-tert-Butyl-3-(4-chlorophenyl)-N-cyclopentyl-2-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877646-95-2C22H27ClN4
![N-Cyclopentyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C18H20N4, CAS 877794-27-9](/s/FCUKOCKCWNINSV-UHFFFAOYSA-N.svg)
N-Cyclopentyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877794-27-9C18H20N4
![N-Cyclopentyl-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24N4O, CAS 904262-14-2](/s/KHJRMZBZSNFWHX-UHFFFAOYSA-N.svg)
N-Cyclopentyl-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 904262-14-2C20H24N4O
![5-tert-Butyl-N-cyclopentyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H28N4, CAS 879569-03-6](/s/XGKIREOAJZOZEE-UHFFFAOYSA-N.svg)
5-tert-Butyl-N-cyclopentyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 879569-03-6C22H28N4
![N-Cyclopentyl-3-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H22N4O, CAS 879575-36-7](/s/YHEWULVGLYZFHD-UHFFFAOYSA-N.svg)
N-Cyclopentyl-3-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 879575-36-7C19H22N4O
![N-Cyclopentyl-3-(3,4-dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H26N4O2, CAS 900297-94-1](/s/BOUDAPBUAGZQPU-UHFFFAOYSA-N.svg)
N-Cyclopentyl-3-(3,4-dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900297-94-1C21H26N4O2
![N-Cyclopentyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24N4, CAS 890629-49-9](/s/YKBVAFFJGCHVGS-UHFFFAOYSA-N.svg)
N-Cyclopentyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 890629-49-9C20H24N4
![3-(2-Chlorophenyl)-N-cyclopentyl-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C18H19ClN4, CAS 890635-83-3](/s/SQYXWRXSMKNSLE-UHFFFAOYSA-N.svg)
3-(2-Chlorophenyl)-N-cyclopentyl-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 890635-83-3C18H19ClN4
![N-Cyclopentyl-2,5-dimethyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24N4, CAS 890638-89-8](/s/WHMWHHSDLIAHSW-UHFFFAOYSA-N.svg)
N-Cyclopentyl-2,5-dimethyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 890638-89-8C20H24N4
![N-Cyclopentyl-5-methyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H22N4, CAS 890612-44-9](/s/IQIOYSSADIHDQS-UHFFFAOYSA-N.svg)
N-Cyclopentyl-5-methyl-3-(4-methylphenyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 890612-44-9C19H22N4
![N-Cyclopentyl-2-ethyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24N4, CAS 890620-87-8](/s/GRNCIPBGNMPFRD-UHFFFAOYSA-N.svg)
N-Cyclopentyl-2-ethyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 890620-87-8C20H24N4
![N-Cyclopentyl-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H24N4, CAS 890627-50-6](/s/VIWLMWVEZCNNBH-UHFFFAOYSA-N.svg)
N-Cyclopentyl-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 890627-50-6C20H24N4
![3-(2-Chlorophenyl)-N-cyclopentyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H21ClN4, CAS 890633-77-9](/s/ZPLWNLHAYHTMFA-UHFFFAOYSA-N.svg)
3-(2-Chlorophenyl)-N-cyclopentyl-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 890633-77-9C19H21ClN4
![N-Cyclopentyl-5-methyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H19F3N4, CAS 890637-50-0](/s/BOHITBQGRQADHZ-UHFFFAOYSA-N.svg)
N-Cyclopentyl-5-methyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 890637-50-0C19H19F3N4
![N-Cyclopentyl-5,6-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H22N4, CAS 890617-91-1](/s/SLHXFJVDLUFKBO-UHFFFAOYSA-N.svg)
N-Cyclopentyl-5,6-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 890617-91-1C19H22N4
![N-Cyclopentyl-3-(4-fluorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C19H21FN4, CAS 1031626-91-1](/s/INDNKTRXQUYXNL-UHFFFAOYSA-N.svg)
N-Cyclopentyl-3-(4-fluorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 1031626-91-1C19H21FN4
- N-Cyclopentyl-3-(4-fluorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine1031654-29-1C18H19FN4
- N-Cyclopentyl-3-(4-fluorophenyl)-5-methyl-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine1031937-58-2C19H18F4N4
- 5-tert-Butyl-N-cyclopentyl-3-(4-fluorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine1031654-82-6C22H27FN4
- N-Cyclopentyl-5-methyl-3-(4-methylphenyl)-2-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-7-amine1031938-06-3C20H21F3N4
Related scaffolds
Same ring framework with different atoms or bond orders
