Murcko scaffold
1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl azetidine-3-carboxylate scaffold
8 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 18
- Chemicals
- 8
- With full pages
- 0
Scaffold SMILES
O=C(ON1C(=O)c2ccccc2C1=O)C1CNC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-acetylazetidine-3-carboxylate
CAS 2248416-17-1C14H12N2O5
1-tert-Butyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) 3-methylazetidine-1,3-dicarboxylate
CAS 2248367-32-8C18H20N2O6
1-tert-Butyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) azetidine-1,3-dicarboxylate
CAS 2170793-65-2C17H18N2O6
1-tert-Butyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) 3-(prop-2-en-1-yl)azetidine-1,3-dicarboxylate
CAS 2248356-68-3C20H22N2O6
1-tert-Butyl 3-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl) 3-methoxyazetidine-1,3-dicarboxylate
CAS 2248326-69-2C18H20N2O7
1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-methanesulfonylazetidine-3-carboxylate
CAS 2248280-48-8C13H12N2O6S
1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(2,2-difluoroethyl)azetidine-3-carboxylate
CAS 2248397-60-4C14H12F2N2O4
1,3-Dioxo-2,3-dihydro-1H-isoindol-2-yl azetidine-3-carboxylate
CAS 2920116-96-5C12H10N2O4