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Murcko scaffold

Ring system with 3 rings and 13 atoms

27 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
27
With full pages
1
Scaffold SMILES

c1cnc2[nH]cc(C3CCC3)c2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cnc2[nH]cc(C3CCC3)c2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine chemical structure, C11H13N3, CAS 1515937-87-7
1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine
CAS 1515937-87-7C11H13N3
1-(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine chemical structure, C12H15N3, CAS 1500606-65-4
1-(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine
CAS 1500606-65-4C12H15N3
1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carboxylic acid chemical structure, C12H12N2O2, CAS 1504762-06-4
1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carboxylic acid
CAS 1504762-06-4C12H12N2O2
1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine chemical structure, C12H15N3, CAS 1521131-60-1
1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine
CAS 1521131-60-1C12H15N3
1-(1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine chemical structure, C13H17N3, CAS 1516128-84-9
1-(1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine
CAS 1516128-84-9C13H17N3
1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carboxylic acid chemical structure, C13H14N2O2, CAS 1537286-65-9
1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carboxylic acid
CAS 1537286-65-9C13H14N2O2
5-Bromo-3-cyclobutyl-1H-pyrrolo(2,3-b)pyridine chemical structure, C11H11BrN2, CAS 1936373-90-8
5-Bromo-3-cyclobutyl-1H-pyrrolo(2,3-b)pyridine
CAS 1936373-90-8C11H11BrN2
3-Cyclobutyl-1H-pyrrolo[2,3-b]pyridin-5-amine chemical structure, C11H13N3, CAS 2138294-34-3
3-Cyclobutyl-1H-pyrrolo[2,3-b]pyridin-5-amine
CAS 2138294-34-3C11H13N3
3-Cyclobutyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid chemical structure, C12H12N2O2, CAS 2138251-44-0
3-Cyclobutyl-1H-pyrrolo[2,3-b]pyridine-5-carboxylic acid
CAS 2138251-44-0C12H12N2O2
3-(Aminomethyl)-3-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-ol chemical structure, C13H17N3O, CAS 2229135-67-3
3-(Aminomethyl)-3-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-ol
CAS 2229135-67-3C13H17N3O
(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanol chemical structure, C12H14N2O, CAS 2228343-77-7
(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanol
CAS 2228343-77-7C12H14N2O
3-Amino-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carboxylic acid chemical structure, C12H13N3O2, CAS 2228741-46-4
3-Amino-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carboxylic acid
CAS 2228741-46-4C12H13N3O2
3,3-Difluoro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine chemical structure, C11H11F2N3, CAS 2229123-59-3
3,3-Difluoro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine
CAS 2229123-59-3C11H11F2N3
3-(Aminomethyl)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-ol chemical structure, C12H15N3O, CAS 2228404-69-9
3-(Aminomethyl)-3-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-ol
CAS 2228404-69-9C12H15N3O
1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carbonitrile chemical structure, C12H11N3, CAS 2228970-63-4
1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carbonitrile
CAS 2228970-63-4C12H11N3
(3,3-Difluoro-1-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine chemical structure, C13H15F2N3, CAS 2228298-39-1
(3,3-Difluoro-1-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine
CAS 2228298-39-1C13H15F2N3
(1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanol chemical structure, C13H16N2O, CAS 2229235-57-6
(1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanol
CAS 2229235-57-6C13H16N2O
2-(1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)ethan-1-amine chemical structure, C14H19N3, CAS 2228187-18-4
2-(1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)ethan-1-amine
CAS 2228187-18-4C14H19N3
2-(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)acetic acid chemical structure, C13H14N2O2, CAS 2229259-56-5
2-(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)acetic acid
CAS 2229259-56-5C13H14N2O2
1-(3,3-Difluoro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine chemical structure, C12H13F2N3, CAS 2229492-84-4
1-(3,3-Difluoro-1-{1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)methanamine
CAS 2229492-84-4C12H13F2N3
1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carbonitrile chemical structure, C13H13N3, CAS 2228225-54-3
1-{1-Methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutane-1-carbonitrile
CAS 2228225-54-3C13H13N3
2-(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)ethan-1-amine chemical structure, C13H17N3, CAS 2229241-58-9
2-(1-{1H-Pyrrolo[2,3-b]pyridin-3-yl}cyclobutyl)ethan-1-amine
CAS 2229241-58-9C13H17N3
3,3-Difluoro-1-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine chemical structure, C12H13F2N3, CAS 2229552-79-6
3,3-Difluoro-1-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-amine
CAS 2229552-79-6C12H13F2N3
3-Amino-3-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-ol chemical structure, C12H15N3O, CAS 2228511-06-4
3-Amino-3-{1-methyl-1H-pyrrolo[2,3-b]pyridin-3-yl}cyclobutan-1-ol
CAS 2228511-06-4C12H15N3O