Murcko scaffold
N-(5-((2-Oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide scaffold
23 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 22
- Chemicals
- 23
- With full pages
- 10
Scaffold SMILES
O=C(CSc1nnc(NC(=O)C2CC2)s1)Nc1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
![N-[5-[2-(4-Fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H13FN4O2S2, CAS 392297-45-9](/s/DGTABNKXLYHMMP-UHFFFAOYSA-N.svg)
N-[5-[2-(4-Fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 392297-45-9C14H13FN4O2S2
N-(5-((2-Oxo-2-((2-(trifluoromethyl)phenyl)amino)ethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392296-91-2C15H13F3N4O2S2
N-(5-((2-Oxo-2-(phenylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392290-74-3C14H14N4O2S2
N-(5-((2-Oxo-2-(m-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392292-00-1C15H16N4O2S2
![N-[5-[2-(4-Methoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C15H16N4O3S2, CAS 392293-59-3](/s/HFQZQBBGSLSGPI-UHFFFAOYSA-N.svg)
N-[5-[2-(4-Methoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 392293-59-3C15H16N4O3S2
![N-[5-[2-(4-Ethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H18N4O3S2, CAS 391869-63-9](/s/FMJXNTKUJXOASW-UHFFFAOYSA-N.svg)
N-[5-[2-(4-Ethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 391869-63-9C16H18N4O3S2
N-(5-((2-((2-Fluorophenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392298-06-5C14H13FN4O2S2
![N-[5-[2-Oxo-2-[3-(trifluoromethyl)anilino]ethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C15H13F3N4O2S2, CAS 604747-89-9](/s/XVIQYZLLGLWKPD-UHFFFAOYSA-N.svg)
N-[5-[2-Oxo-2-[3-(trifluoromethyl)anilino]ethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 604747-89-9C15H13F3N4O2S2
![N-[5-[2-(2,5-Dimethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H18N4O4S2, CAS 842972-84-3](/s/YAUICKAUEUGINT-UHFFFAOYSA-N.svg)
N-[5-[2-(2,5-Dimethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 842972-84-3C16H18N4O4S2
N-(5-((2-Oxo-2-(p-tolylamino)ethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392291-35-9C15H16N4O2S2
N-(5-((2-((2,3-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392294-25-6C16H18N4O2S2
N-(5-((2-((2,4-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392295-57-7C16H18N4O2S2
N-(5-((2-((2,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392294-93-8C16H18N4O2S2
N-(5-((2-((3,5-Dimethylphenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392296-19-4C16H18N4O2S2
![Ethyl 4-{2-[(5-cyclopropaneamido-1,3,4-thiadiazol-2-yl)sulfanyl]acetamido}benzoate chemical structure, C17H18N4O4S2, CAS 389072-38-2](/s/HBYAPVNQNDWDOO-UHFFFAOYSA-N.svg)
Ethyl 4-{2-[(5-cyclopropaneamido-1,3,4-thiadiazol-2-yl)sulfanyl]acetamido}benzoate
CAS 389072-38-2C17H18N4O4S2
N-(5-((2-((2-Chloro-5-(trifluoromethyl)phenyl)amino)-2-oxoethyl)thio)-1,3,4-thiadiazol-2-yl)cyclopropanecarboxamide
CAS 392298-95-2C15H12ClF3N4O2S2
![N-[5-[2-Oxo-2-[4-(trifluoromethyl)anilino]ethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C15H13F3N4O2S2, CAS 868975-04-6](/s/JBQPIJXLHPCEPR-UHFFFAOYSA-N.svg)
N-[5-[2-Oxo-2-[4-(trifluoromethyl)anilino]ethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 868975-04-6C15H13F3N4O2S2
![N-[5-[2-(3-Fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H13FN4O2S2, CAS 893330-85-3](/s/QEUCPZGVZCFKEA-UHFFFAOYSA-N.svg)
N-[5-[2-(3-Fluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 893330-85-3C14H13FN4O2S2
![N-[5-[2-(2,4-Difluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C14H12F2N4O2S2, CAS 893330-92-2](/s/BNSLPMSTHKSDTA-UHFFFAOYSA-N.svg)
N-[5-[2-(2,4-Difluoroanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 893330-92-2C14H12F2N4O2S2
![N-[5-[2-(3,4-Dimethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H18N4O4S2, CAS 893331-15-2](/s/QPZOIZBQVKNTPP-UHFFFAOYSA-N.svg)
N-[5-[2-(3,4-Dimethoxyanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 893331-15-2C16H18N4O4S2
![N-[5-[2-(4-Acetylanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H16N4O3S2, CAS 893331-72-1](/s/NWNKZPOQTKDWGP-UHFFFAOYSA-N.svg)
N-[5-[2-(4-Acetylanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 893331-72-1C16H16N4O3S2
![N-[5-[2-(3-Acetamidoanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H17N5O3S2, CAS 893331-79-8](/s/YRAIGPNZEGSRGA-UHFFFAOYSA-N.svg)
N-[5-[2-(3-Acetamidoanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 893331-79-8C16H17N5O3S2
![N-[5-[2-(4-Acetamidoanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide chemical structure, C16H17N5O3S2, CAS 893331-86-7](/s/HQBZPRVVNQIJQA-UHFFFAOYSA-N.svg)
N-[5-[2-(4-Acetamidoanilino)-2-oxoethyl]sulfanyl-1,3,4-thiadiazol-2-yl]cyclopropanecarboxamide
CAS 893331-86-7C16H17N5O3S2