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Murcko scaffold

Ring system with 4 rings and 32 atoms

10 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
32
Chemicals
10
With full pages
1
Scaffold SMILES

O=C1C=CC=CCCCCCCCCCC=CC(=O)c2cccc3c2C(=O)C=C(N1)C3=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=CC=CCCCCCCCCCC=CC(=O)c2cccc3c2C(=O)C=C(N1)C3=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Damavaricin C chemical structure, C37H47NO13, CAS 58849-86-8
Damavaricin C
CAS 58849-86-8C37H47NO13
Awamycin chemical structure, C38H49NO12S, CAS 87913-35-7
Awamycin
CAS 87913-35-7C38H49NO12S
(7Z,18E,20Z)-4,10,12,14,16-Pentahydroxy-9-(hydroxymethyl)-3,7,11,13,15,17,21-heptamethyl-23-azatricyclo[22.3.1.05,27]octacosa-1(27),2,4,7,18,20,24-heptaene-6,22,26,28-tetrone chemical structure, C35H45NO10
(7Z,18E,20Z)-4,10,12,14,16-Pentahydroxy-9-(hydroxymethyl)-3,7,11,13,15,17,21-heptamethyl-23-azatricyclo[22.3.1.05,27]octacosa-1(27),2,4,7,18,20,24-heptaene-6,22,26,28-tetrone
C35H45NO10
Rifamycin W chemical structure, C35H45NO11, CAS 53904-81-7
Rifamycin W
CAS 53904-81-7C35H45NO11
Proansamycin B chemical structure, C35H45NO9, CAS 442903-92-6
Proansamycin B
CAS 442903-92-6C35H45NO9
34a-Deoxy-rifamycin W chemical structure, C35H45NO10, CAS 442871-33-2
34a-Deoxy-rifamycin W
CAS 442871-33-2C35H45NO10
Protorifamycin I chemical structure, C35H45NO10, CAS 69239-55-0
Protorifamycin I
CAS 69239-55-0C35H45NO10
31-Homorifamycin W chemical structure, C36H47NO11, CAS 157049-51-9
31-Homorifamycin W
CAS 157049-51-9C36H47NO11
30-Hydroxyrifamycin W chemical structure, C35H45NO12, CAS 79473-23-7
30-Hydroxyrifamycin W
CAS 79473-23-7C35H45NO12
(6Z,8E,10S,11S,12R,13R,14R,15R,16R,17S,18R,19E)-11,12,13,14,15,16,17,18-Octahydro-11,13,15,17,22-pentahydroxy-18-(hydroxymethyl)-6,10,12,14,16,20,23-heptamethyl-3,25-methano-1H-4-benzazacyclotricosine-1,5,21,26(4H,10H)-tetrone chemical structure, C35H45NO10
(6Z,8E,10S,11S,12R,13R,14R,15R,16R,17S,18R,19E)-11,12,13,14,15,16,17,18-Octahydro-11,13,15,17,22-pentahydroxy-18-(hydroxymethyl)-6,10,12,14,16,20,23-heptamethyl-3,25-methano-1H-4-benzazacyclotricosine-1,5,21,26(4H,10H)-tetrone
C35H45NO10