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Murcko scaffold

Ring system with 4 rings and 25 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
13
With full pages
3
Scaffold SMILES

O=C(Nn1cc(C=C2N=c3ccccc3=N2)sc1=S)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nn1cc(C=C2N=c3ccccc3=N2)sc1=S)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-4-bromobenzamide chemical structure, C18H11BrN4O2S2, CAS 307342-39-8
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-4-bromobenzamide
CAS 307342-39-8C18H11BrN4O2S2
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-methoxybenzamide chemical structure, C19H14N4O3S2, CAS 881818-53-7
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-methoxybenzamide
CAS 881818-53-7C19H14N4O3S2
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-2-hydroxybenzamide chemical structure, C18H12N4O3S2, CAS 881818-43-5
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-2-hydroxybenzamide
CAS 881818-43-5C18H12N4O3S2
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-4-chlorobenzamide chemical structure, C18H11ClN4O2S2, CAS 881821-74-5
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-4-chlorobenzamide
CAS 881821-74-5C18H11ClN4O2S2
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2,4-dichlorobenzamide chemical structure, C18H10Cl2N4O2S2, CAS 881818-78-6
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2,4-dichlorobenzamide
CAS 881818-78-6C18H10Cl2N4O2S2
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide chemical structure, C18H12N4O2S2, CAS 1164565-85-8
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide
CAS 1164565-85-8C18H12N4O2S2
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-2-chlorobenzamide chemical structure, C18H11ClN4O2S2, CAS 1164453-74-0
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-2-chlorobenzamide
CAS 1164453-74-0C18H11ClN4O2S2
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-3-chlorobenzamide chemical structure, C18H11ClN4O2S2, CAS 1164453-62-6
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-3-chlorobenzamide
CAS 1164453-62-6C18H11ClN4O2S2
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-bromobenzamide chemical structure, C18H11BrN4O2S2, CAS 881818-73-1
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-bromobenzamide
CAS 881818-73-1C18H11BrN4O2S2
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-4-methylbenzamide chemical structure, C19H14N4O2S2, CAS 1164549-41-0
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-4-methylbenzamide
CAS 1164549-41-0C19H14N4O2S2
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-methylbenzamide chemical structure, C19H14N4O2S2, CAS 881818-33-3
N-[(5Z)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-2-methylbenzamide
CAS 881818-33-3C19H14N4O2S2
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-4-fluorobenzamide chemical structure, C18H11FN4O2S2, CAS 881818-68-4
N-[(5E)-5-(1H-Benzimidazol-2-ylmethylidene)-4-oxo-2-thioxo-1,3-thiazolidin-3-yl]-4-fluorobenzamide
CAS 881818-68-4C18H11FN4O2S2
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-3-nitrobenzamide chemical structure, C18H11N5O4S2, CAS 881818-83-3
(Z)-N-(5-((1H-Benzo[d]imidazol-2-yl)methylene)-4-oxo-2-thioxothiazolidin-3-yl)-3-nitrobenzamide
CAS 881818-83-3C18H11N5O4S2