Murcko scaffold
Ring system with 5 rings and 36 atoms
14 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 36
- Chemicals
- 14
- With full pages
- 12
Scaffold SMILES
O=C1C(=O)N(CCN2CCOCC2)C(c2ccccc2)C1=Cc1ccc(OCc2ccccc2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 14 of 14 chemicals
![4-[4-(Benzyloxy)benzoyl]-3-hydroxy-1-[2-(morpholin-4-yl)ethyl]-5-phenyl-2,5-dihydro-1H-pyrrol-2-one chemical structure, C30H30N2O5](/s/AGLBSQAZBLLMEH-UHFFFAOYSA-N.svg)
4-[4-(Benzyloxy)benzoyl]-3-hydroxy-1-[2-(morpholin-4-yl)ethyl]-5-phenyl-2,5-dihydro-1H-pyrrol-2-one
C30H30N2O5
![4-[4-(Benzyloxy)-2-methylbenzoyl]-5-(3-bromophenyl)-3-hydroxy-1-[2-(4-morpholinyl)ethyl]-1,5-dihydro-2H-pyrrol-2-one chemical structure, C31H31BrN2O5, CAS 500278-49-9](/s/DWKYDHCMBARGNA-OHYPFYFLSA-N.svg)
4-[4-(Benzyloxy)-2-methylbenzoyl]-5-(3-bromophenyl)-3-hydroxy-1-[2-(4-morpholinyl)ethyl]-1,5-dihydro-2H-pyrrol-2-one
CAS 500278-49-9C31H31BrN2O5
4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(3-ethoxy-4-hydroxyphenyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 488841-73-2C33H36N2O7
4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(3,4-dimethoxyphenyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 488732-72-5C33H36N2O7
4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(4-tert-butylphenyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 497248-21-2C35H40N2O5
![4-[4-(Benzyloxy)-2-methylbenzoyl]-3-hydroxy-5-(4-methylphenyl)-1-[2-(4-morpholinyl)ethyl]-1,5-dihydro-2H-pyrrol-2-one chemical structure, C32H34N2O5, CAS 489440-58-6](/s/RIUCRDRBXJNAFP-SJCQXOIGSA-N.svg)
4-[4-(Benzyloxy)-2-methylbenzoyl]-3-hydroxy-5-(4-methylphenyl)-1-[2-(4-morpholinyl)ethyl]-1,5-dihydro-2H-pyrrol-2-one
CAS 489440-58-6C32H34N2O5
4-(4-(Benzyloxy)-2-methylbenzoyl)-3-hydroxy-5-(4-hydroxy-3-methoxyphenyl)-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 496775-44-1C32H34N2O7
4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(3,4-dichlorophenyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 488731-77-7C31H30Cl2N2O5
4-(4-(Benzyloxy)benzoyl)-3-hydroxy-1-(2-morpholinoethyl)-5-phenyl-1H-pyrrol-2(5H)-one
CAS 848867-71-0C30H30N2O5
![4-[4-(Benzyloxy)-2-methylbenzoyl]-5-(4-fluorophenyl)-3-hydroxy-1-[2-(4-morpholinyl)ethyl]-1,5-dihydro-2H-pyrrol-2-one chemical structure, C31H31FN2O5, CAS 488811-70-7](/s/RZUASUGGNPKFOL-OHYPFYFLSA-N.svg)
4-[4-(Benzyloxy)-2-methylbenzoyl]-5-(4-fluorophenyl)-3-hydroxy-1-[2-(4-morpholinyl)ethyl]-1,5-dihydro-2H-pyrrol-2-one
CAS 488811-70-7C31H31FN2O5
![4-[4-(Benzyloxy)-2-methylbenzoyl]-3-hydroxy-1-[2-(4-morpholinyl)ethyl]-5-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one chemical structure, C31H31N3O7, CAS 488134-69-6](/s/MBDLTFFHSFKEFT-OHYPFYFLSA-N.svg)
4-[4-(Benzyloxy)-2-methylbenzoyl]-3-hydroxy-1-[2-(4-morpholinyl)ethyl]-5-(3-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 488134-69-6C31H31N3O7
4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(4-ethoxy-3-methoxyphenyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 497244-14-1C34H38N2O7
4-(4-(Benzyloxy)-2-methylbenzoyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-5-(4-nitrophenyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 487022-90-2C31H31N3O7
4-(4-(Benzyloxy)-2-methylbenzoyl)-5-(4-ethylphenyl)-3-hydroxy-1-(2-(4-morpholinyl)ethyl)-1,5-dihydro-2H-pyrrol-2-one
CAS 488121-40-0C33H36N2O5