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Murcko scaffold

Ring system with 3 rings and 20 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
20
Chemicals
8
With full pages
3
Scaffold SMILES

O=C(CN1C(=O)COc2ccccc21)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CN1C(=O)COc2ccccc21)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4-[2-(4-Hydroxy-piperidin-1-yl)-2-oxo-ethyl]-6-methyl-4H-benzo[1,4]oxazin-3-one chemical structure, C16H20N2O4, CAS 606119-71-5
4-[2-(4-Hydroxy-piperidin-1-yl)-2-oxo-ethyl]-6-methyl-4H-benzo[1,4]oxazin-3-one
CAS 606119-71-5C16H20N2O4
6-Chloro-4-(2-oxo-2-piperidin-1-ylethyl)-1,4-benzoxazin-3-one chemical structure, C15H17ClN2O3, CAS 26509-22-8
6-Chloro-4-(2-oxo-2-piperidin-1-ylethyl)-1,4-benzoxazin-3-one
CAS 26509-22-8C15H17ClN2O3
6-Methyl-4-[2-(3-methyl-piperidin-1-yl)-2-oxo-ethyl]-4H-benzo[1,4]oxazin-3-one chemical structure, C17H22N2O3, CAS 606119-46-4
6-Methyl-4-[2-(3-methyl-piperidin-1-yl)-2-oxo-ethyl]-4H-benzo[1,4]oxazin-3-one
CAS 606119-46-4C17H22N2O3
Piperidine, 1-[(2,3-dihydro-6-methyl-3-oxo-4H-1,4-benzoxazin-4-yl)acetyl]-2,6-dimethyl- chemical structure, C18H24N2O3, CAS 606119-48-6
Piperidine, 1-[(2,3-dihydro-6-methyl-3-oxo-4H-1,4-benzoxazin-4-yl)acetyl]-2,6-dimethyl-
CAS 606119-48-6C18H24N2O3
2,6-Dimethyl-4-[2-(3-methylpiperidin-1-yl)-2-oxoethyl]-1,4-benzoxazin-3-one chemical structure, C18H24N2O3, CAS 606119-95-3
2,6-Dimethyl-4-[2-(3-methylpiperidin-1-yl)-2-oxoethyl]-1,4-benzoxazin-3-one
CAS 606119-95-3C18H24N2O3
8-Chloro-4-[2-(3,5-dimethylpiperidin-1-yl)-2-oxoethyl]-2H-1,4-benzoxazin-3(4H)-one chemical structure, C17H21ClN2O3, CAS 925592-42-3
8-Chloro-4-[2-(3,5-dimethylpiperidin-1-yl)-2-oxoethyl]-2H-1,4-benzoxazin-3(4H)-one
CAS 925592-42-3C17H21ClN2O3
Methyl 1-[(6-methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetyl]piperidine-4-carboxylate chemical structure, C18H22N2O5, CAS 938019-63-7
Methyl 1-[(6-methyl-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)acetyl]piperidine-4-carboxylate
CAS 938019-63-7C18H22N2O5
6-Amino-2-ethyl-4-[2-oxo-2-(piperidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazin-3-one chemical structure, C17H23N3O3, CAS 1018576-75-4
6-Amino-2-ethyl-4-[2-oxo-2-(piperidin-1-yl)ethyl]-3,4-dihydro-2H-1,4-benzoxazin-3-one
CAS 1018576-75-4C17H23N3O3