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Murcko scaffold

Ring system with 5 rings and 27 atoms

11 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
27
Chemicals
11
With full pages
5
Scaffold SMILES

O=C(c1ccccc1)N1CCN2C(=O)c3ccccc3C12c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(c1ccccc1)N1CCN2C(=O)c3ccccc3C12c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

1-Benzoyl-9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one chemical structure, C23H17ClN2O2, CAS 477867-90-6
1-Benzoyl-9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one
CAS 477867-90-6C23H17ClN2O2
9b-(4-Chlorophenyl)-1-(4-methylbenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one chemical structure, C24H19ClN2O2, CAS 477886-49-0
9b-(4-Chlorophenyl)-1-(4-methylbenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one
CAS 477886-49-0C24H19ClN2O2
9b-(4-Chlorophenyl)-1-(4-fluorobenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one chemical structure, C23H16ClFN2O2, CAS 477886-50-3
9b-(4-Chlorophenyl)-1-(4-fluorobenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one
CAS 477886-50-3C23H16ClFN2O2
9b-(4-Chlorophenyl)-1-(3-methoxybenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one chemical structure, C24H19ClN2O3, CAS 477886-54-7
9b-(4-Chlorophenyl)-1-(3-methoxybenzoyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one
CAS 477886-54-7C24H19ClN2O3
1-(4-Methylbenzoyl)-9b-phenyl-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one chemical structure, C24H20N2O2, CAS 338414-88-3
1-(4-Methylbenzoyl)-9b-phenyl-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one
CAS 338414-88-3C24H20N2O2
1-(4-Fluorobenzoyl)-9b-phenyl-1H,2H,3H,5H,9bH-imidazo[2,1-a]isoindol-5-one chemical structure, C23H17FN2O2, CAS 327979-63-5
1-(4-Fluorobenzoyl)-9b-phenyl-1H,2H,3H,5H,9bH-imidazo[2,1-a]isoindol-5-one
CAS 327979-63-5C23H17FN2O2
Ml375 chemical structure, C23H15ClF2N2O2, CAS 1488362-55-5
Ml375
CAS 1488362-55-5C23H15ClF2N2O2
(9bR)-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one chemical structure, C23H15ClF2N2O2, CAS 1488362-56-6
(9bR)-9b-(4-Chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
CAS 1488362-56-6C23H15ClF2N2O2
VU 6008667 chemical structure, C24H17ClF2N2O2, CAS 2092923-21-0
VU 6008667
CAS 2092923-21-0C24H17ClF2N2O2
(Rac)-VU 6008667 chemical structure, C24H17ClF2N2O2, CAS 2092917-63-8
(Rac)-VU 6008667
CAS 2092917-63-8C24H17ClF2N2O2
(R)-VU 6008667 chemical structure, C24H17ClF2N2O2, CAS 2097818-14-7
(R)-VU 6008667
CAS 2097818-14-7C24H17ClF2N2O2