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Murcko scaffold

Ring system with 3 rings and 25 atoms

23 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
25
Chemicals
23
With full pages
13
Scaffold SMILES

O=C(N1CCNCC1)N(Cc1ccccc1)S(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(N1CCNCC1)N(Cc1ccccc1)S(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 23 of 23 chemicals

4-Methyl-N-(2-methylbenzyl)-N-tosylpiperazine-1-carboxamide chemical structure, C21H27N3O3S, CAS 887196-82-9
4-Methyl-N-(2-methylbenzyl)-N-tosylpiperazine-1-carboxamide
CAS 887196-82-9C21H27N3O3S
4-Methyl-N-(3-methylbenzyl)-N-tosylpiperazine-1-carboxamide chemical structure, C21H27N3O3S, CAS 887196-84-1
4-Methyl-N-(3-methylbenzyl)-N-tosylpiperazine-1-carboxamide
CAS 887196-84-1C21H27N3O3S
N-(2,5-Dimethylbenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C22H29N3O3S, CAS 887196-85-2
N-(2,5-Dimethylbenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887196-85-2C22H29N3O3S
4-Methyl-N-(4-methylbenzyl)-N-tosylpiperazine-1-carboxamide chemical structure, C21H27N3O3S, CAS 887196-86-3
4-Methyl-N-(4-methylbenzyl)-N-tosylpiperazine-1-carboxamide
CAS 887196-86-3C21H27N3O3S
N-(4-Fluorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H24FN3O3S, CAS 899991-57-2
N-(4-Fluorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 899991-57-2C20H24FN3O3S
N-(4-Chlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H24ClN3O3S, CAS 887196-97-6
N-(4-Chlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887196-97-6C20H24ClN3O3S
N-(2-Chlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H24ClN3O3S, CAS 887196-99-8
N-(2-Chlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887196-99-8C20H24ClN3O3S
N-(2-Fluorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H24FN3O3S, CAS 887197-00-4
N-(2-Fluorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887197-00-4C20H24FN3O3S
N-(3-Chlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H24ClN3O3S, CAS 887197-01-5
N-(3-Chlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887197-01-5C20H24ClN3O3S
N-(2,5-Dimethylbenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide chemical structure, C23H31N3O3S, CAS 887197-04-8
N-(2,5-Dimethylbenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide
CAS 887197-04-8C23H31N3O3S
N-(4-Bromobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H24BrN3O3S, CAS 887196-96-5
N-(4-Bromobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887196-96-5C20H24BrN3O3S
N-(2-Chloro-6-fluorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H23ClFN3O3S, CAS 887196-98-7
N-(2-Chloro-6-fluorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887196-98-7C20H23ClFN3O3S
N-(3,4-Dichlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H23Cl2N3O3S, CAS 899745-00-7
N-(3,4-Dichlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 899745-00-7C20H23Cl2N3O3S
N-(2,4-Dichlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C20H23Cl2N3O3S, CAS 887197-02-6
N-(2,4-Dichlorobenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887197-02-6C20H23Cl2N3O3S
N-(4-Bromobenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide chemical structure, C21H26BrN3O3S, CAS 899949-37-2
N-(4-Bromobenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide
CAS 899949-37-2C21H26BrN3O3S
N-(4-Chlorobenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide chemical structure, C21H26ClN3O3S, CAS 887197-05-9
N-(4-Chlorobenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide
CAS 887197-05-9C21H26ClN3O3S
N-(3,4-Dichlorobenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide chemical structure, C21H25Cl2N3O3S, CAS 899745-06-3
N-(3,4-Dichlorobenzyl)-4-ethyl-N-tosylpiperazine-1-carboxamide
CAS 899745-06-3C21H25Cl2N3O3S
N-(3,5-Dimethoxybenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide chemical structure, C22H29N3O5S, CAS 887196-88-5
N-(3,5-Dimethoxybenzyl)-4-methyl-N-tosylpiperazine-1-carboxamide
CAS 887196-88-5C22H29N3O5S
4-Methyl-N-(4-nitrobenzyl)-N-tosylpiperazine-1-carboxamide chemical structure, C20H24N4O5S, CAS 887196-83-0
4-Methyl-N-(4-nitrobenzyl)-N-tosylpiperazine-1-carboxamide
CAS 887196-83-0C20H24N4O5S
4-Methyl-N-(3-nitrobenzyl)-N-tosylpiperazine-1-carboxamide chemical structure, C20H24N4O5S, CAS 899991-45-8
4-Methyl-N-(3-nitrobenzyl)-N-tosylpiperazine-1-carboxamide
CAS 899991-45-8C20H24N4O5S
Methyl 4-((4-methyl-N-tosylpiperazine-1-carboxamido)methyl)benzoate chemical structure, C22H27N3O5S, CAS 899744-84-4
Methyl 4-((4-methyl-N-tosylpiperazine-1-carboxamido)methyl)benzoate
CAS 899744-84-4C22H27N3O5S
4-Methyl-N-tosyl-N-(3-(trifluoromethyl)benzyl)piperazine-1-carboxamide chemical structure, C21H24F3N3O3S, CAS 899949-27-0
4-Methyl-N-tosyl-N-(3-(trifluoromethyl)benzyl)piperazine-1-carboxamide
CAS 899949-27-0C21H24F3N3O3S
4-Methyl-N-tosyl-N-(4-(trifluoromethyl)benzyl)piperazine-1-carboxamide chemical structure, C21H24F3N3O3S, CAS 899991-61-8
4-Methyl-N-tosyl-N-(4-(trifluoromethyl)benzyl)piperazine-1-carboxamide
CAS 899991-61-8C21H24F3N3O3S