Murcko scaffold

N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)thiophene-2-carboxamide scaffold

17 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 20
Chemicals: 17
With full pages: 1

Scaffold SMILES

O=C(Nc1nc2cc3c(cc2s1)OCO3)c1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)thiophene-2-carboxamide page

Murcko scaffold O=C(Nc1nc2cc3c(cc2s1)OCO3)c1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 17 of 17 chemicals

N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)thiophene-2-carboxamide

CAS 892855-22-0C₁₃H₈N₂O₃S₂

N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)-5-nitrothiophene-2-carboxamide

CAS 892856-56-3C₁₃H₇N₃O₅S₂

5-Bromo-N-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-yl)thiophene-2-carboxamide

CAS 892857-19-1C₁₃H₇BrN₂O₃S₂

5-Chloro-N-([1,3]dioxolo[4,5-f][1,3]benzothiazol-6-yl)thiophene-2-carboxamide

CAS 892857-27-1C₁₃H₇ClN₂O₃S₂

N-[3-(Dimethylamino)propyl]-N-[1,3]dioxolo[4,5-f][1,3]benzothiazol-6-ylthiophene-2-carboxamide

CAS 1052539-21-5C₁₈H₂₀ClN₃O₃S₂

$5-Bromo-N-[2-(diethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride chemical structure, C19H21BrClN3O3S2, CAS 1052529-78-8$

5-Bromo-N-[2-(diethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride

CAS 1052529-78-8C₁₉H₂₁BrClN₃O₃S₂

N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-5-bromo-N-(3-(dimethylamino)propyl)thiophene-2-carboxamide hydrochloride

CAS 1052537-54-8C₁₈H₁₉BrClN₃O₃S₂

N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-N-(2-(dimethylamino)ethyl)thiophene-2-carboxamide hydrochloride

CAS 1215731-83-1C₁₇H₁₈ClN₃O₃S₂

$5-Bromo-N-[2-(dimethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride chemical structure, C17H17BrClN3O3S2, CAS 1216988-42-9$

5-Bromo-N-[2-(dimethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride

CAS 1216988-42-9C₁₇H₁₇BrClN₃O₃S₂

N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-5-chloro-N-(2-(dimethylamino)ethyl)thiophene-2-carboxamide hydrochloride

CAS 1216629-62-7C₁₇H₁₇Cl₂N₃O₃S₂

$5-Chloro-N-[2-(diethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride chemical structure, C19H21Cl2N3O3S2, CAS 1215804-85-5$

5-Chloro-N-[2-(diethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride

CAS 1215804-85-5C₁₉H₂₁Cl₂N₃O₃S₂

$5-Chloro-N-[3-(dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride chemical structure, C18H19Cl2N3O3S2, CAS 1217029-17-8$

5-Chloro-N-[3-(dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}thiophene-2-carboxamide hydrochloride

CAS 1217029-17-8C₁₈H₁₉Cl₂N₃O₃S₂

$Ethyl 2-[(11Z)-11-[(thiophene-2-carbonyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate chemical structure, C17H14N2O5S2, CAS 905661-37-2$

Ethyl 2-[(11Z)-11-[(thiophene-2-carbonyl)imino]-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-12-yl]acetate

CAS 905661-37-2C₁₇H₁₄N₂O₅S₂

$5-Chloro-N-[(11Z)-12-propyl-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-11-ylidene]thiophene-2-carboxamide chemical structure, C16H13ClN2O3S2, CAS 899362-38-0$

5-Chloro-N-[(11Z)-12-propyl-4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7-trien-11-ylidene]thiophene-2-carboxamide

CAS 899362-38-0C₁₆H₁₃ClN₂O₃S₂

(Z)-N-(7-(2-(Methylthio)ethyl)-[1,3]dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6(7H)-ylidene)thiophene-2-carboxamide

CAS 1007063-68-4C₁₆H₁₄N₂O₃S₃

$N-[2-(Dimethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-5-nitrothiophene-2-carboxamide hydrochloride chemical structure, C17H17ClN4O5S2, CAS 1322016-72-7$

N-[2-(Dimethylamino)ethyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-5-nitrothiophene-2-carboxamide hydrochloride

CAS 1322016-72-7C₁₇H₁₇ClN₄O₅S₂

$N-[3-(Dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-5-nitrothiophene-2-carboxamide hydrochloride chemical structure, C18H19ClN4O5S2, CAS 1321923-44-7$

N-[3-(Dimethylamino)propyl]-N-{4,6-dioxa-10-thia-12-azatricyclo[7.3.0.0^{3,7}]dodeca-1(9),2,7,11-tetraen-11-yl}-5-nitrothiophene-2-carboxamide hydrochloride

CAS 1321923-44-7C₁₈H₁₉ClN₄O₅S₂

N-([1,3]Dioxolo[4,5-f][1,3]benzothiazol-6-yl)thiophene-2-carboxamide scaffold

Chemicals with this scaffold

Related scaffolds