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Murcko scaffold

2-Azabicyclo[5.1.0]octane scaffold

31 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
31
With full pages
4
Scaffold SMILES

C1CCC2CC2NC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Azabicyclo[5.1.0]octane page
Murcko scaffold C1CCC2CC2NC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 31 of 31 chemicals

1-(8,8-Dichloro-1-methoxy-2-azabicyclo[5.1.0]octan-2-yl)ethan-1-one chemical structure, C10H15Cl2NO2, CAS 61803-07-4
1-(8,8-Dichloro-1-methoxy-2-azabicyclo[5.1.0]octan-2-yl)ethan-1-one
CAS 61803-07-4C10H15Cl2NO2
(1R,7R,8S)-8-(Trifluoromethyl)-2-azabicyclo[5.1.0]octane hydrochloride chemical structure, C8H13ClF3N, CAS 2408937-70-0
(1R,7R,8S)-8-(Trifluoromethyl)-2-azabicyclo[5.1.0]octane hydrochloride
CAS 2408937-70-0C8H13ClF3N
(1R,7R,8R)-8-(Trifluoromethyl)-2-azabicyclo[5.1.0]octane hydrochloride chemical structure, C8H13ClF3N, CAS 2408938-06-5
(1R,7R,8R)-8-(Trifluoromethyl)-2-azabicyclo[5.1.0]octane hydrochloride
CAS 2408938-06-5C8H13ClF3N
(1R,7R,8R)-8-(Trifluoromethyl)-2-azabicyclo[5.1.0]octane chemical structure, C8H12F3N, CAS 1932192-96-5
(1R,7R,8R)-8-(Trifluoromethyl)-2-azabicyclo[5.1.0]octane
CAS 1932192-96-5C8H12F3N
8,8-Difluoro-2-azabicyclo[5.1.0]octane chemical structure, C7H11F2N, CAS 1240526-61-7
8,8-Difluoro-2-azabicyclo[5.1.0]octane
CAS 1240526-61-7C7H11F2N
2-Azabicyclo[5.1.0]octane chemical structure, C7H13N, CAS 20437-19-8
2-Azabicyclo[5.1.0]octane
CAS 20437-19-8C7H13N
rac-(1R,7R,8R)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[5.1.0]octane-8-carboxylic acid chemical structure, C13H21NO4, CAS 1308650-44-3
rac-(1R,7R,8R)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[5.1.0]octane-8-carboxylic acid
CAS 1308650-44-3C13H21NO4
2-[(tert-Butoxy)carbonyl]-2-azabicyclo[5.1.0]octane-8-carboxylic acid chemical structure, C13H21NO4, CAS 1784079-42-0
2-[(tert-Butoxy)carbonyl]-2-azabicyclo[5.1.0]octane-8-carboxylic acid
CAS 1784079-42-0C13H21NO4
2-Azabicyclo[5.1.0]octan-8-amine chemical structure, C7H14N2, CAS 1367992-88-8
2-Azabicyclo[5.1.0]octan-8-amine
CAS 1367992-88-8C7H14N2
2-Azabicyclo(5.1.0)octane-2-carboxylic acid, 8,8-difluoro-, 1,1-dimethylethyl ester chemical structure, C12H19F2NO2, CAS 1704724-77-5
2-Azabicyclo(5.1.0)octane-2-carboxylic acid, 8,8-difluoro-, 1,1-dimethylethyl ester
CAS 1704724-77-5C12H19F2NO2
rac-(1R,7R,8S)-2-Azabicyclo(5.1.0)octan-8-amine chemical structure, C7H14N2, CAS 2138565-42-9
rac-(1R,7R,8S)-2-Azabicyclo(5.1.0)octan-8-amine
CAS 2138565-42-9C7H14N2
(1S,7S,8S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[5.1.0]octane-8-carboxylic acid chemical structure, C13H21NO4, CAS 2416218-27-2
(1S,7S,8S)-2-[(tert-Butoxy)carbonyl]-2-azabicyclo[5.1.0]octane-8-carboxylic acid
CAS 2416218-27-2C13H21NO4
8,8-Difluoro-2-azabicyclo[5.1.0]octane 2,2,2-trifluoroacetate chemical structure, C9H12F5NO2, CAS 1704724-80-0
8,8-Difluoro-2-azabicyclo[5.1.0]octane 2,2,2-trifluoroacetate
CAS 1704724-80-0C9H12F5NO2
tert-Butyl 8-amino-2-azabicyclo(5.1.0)octane-2-carboxylate chemical structure, C12H22N2O2, CAS 2155852-87-0
tert-Butyl 8-amino-2-azabicyclo(5.1.0)octane-2-carboxylate
CAS 2155852-87-0C12H22N2O2
tert-Butyl n-{2-azabicyclo[5.1.0]octan-8-yl}carbamate chemical structure, C12H22N2O2, CAS 2171869-46-6
tert-Butyl n-{2-azabicyclo[5.1.0]octan-8-yl}carbamate
CAS 2171869-46-6C12H22N2O2
2-Azabicyclo[5.1.0]octane hydrochloride chemical structure, C7H14ClN, CAS 2445791-14-8
2-Azabicyclo[5.1.0]octane hydrochloride
CAS 2445791-14-8C7H14ClN
2-tert-Butyl 8-chloromethyl (1S,7S,8S)-2-azabicyclo[5.1.0]octane-2,8-dicarboxylate chemical structure, C14H22ClNO4, CAS 2137095-28-2
2-tert-Butyl 8-chloromethyl (1S,7S,8S)-2-azabicyclo[5.1.0]octane-2,8-dicarboxylate
CAS 2137095-28-2C14H22ClNO4
tert-Butyl 2-azabicyclo[5.1.0]octane-2-carboxylate chemical structure, C12H21NO2, CAS 2137722-40-6
tert-Butyl 2-azabicyclo[5.1.0]octane-2-carboxylate
CAS 2137722-40-6C12H21NO2
8,8-Difluoro-2-azabicyclo[5.1.0]octane hydrochloride chemical structure, C7H12ClF2N, CAS 2742660-42-8
8,8-Difluoro-2-azabicyclo[5.1.0]octane hydrochloride
CAS 2742660-42-8C7H12ClF2N
rac-(1R,7R,8R)-2-Azabicyclo[5.1.0]octane-8-carboxylic acid chemical structure, C8H13NO2, CAS 2580092-18-6
rac-(1R,7R,8R)-2-Azabicyclo[5.1.0]octane-8-carboxylic acid
CAS 2580092-18-6C8H13NO2
2-tert-Butyl 8-chloromethyl 2-azabicyclo[5.1.0]octane-2,8-dicarboxylate chemical structure, C14H22ClNO4, CAS 2138256-76-3
2-tert-Butyl 8-chloromethyl 2-azabicyclo[5.1.0]octane-2,8-dicarboxylate
CAS 2138256-76-3C14H22ClNO4
(1S,7R,8S)-8-Fluoro-2-azabicyclo[5.1.0]octane chemical structure, C7H12FN, CAS 3079349-48-4
(1S,7R,8S)-8-Fluoro-2-azabicyclo[5.1.0]octane
CAS 3079349-48-4C7H12FN
Rel-(1S,7R,8R)-8-fluoro-2-azabicyclo[5.1.0]octane chemical structure, C7H12FN, CAS 3079346-41-8
Rel-(1S,7R,8R)-8-fluoro-2-azabicyclo[5.1.0]octane
CAS 3079346-41-8C7H12FN
Rel-(1R,7S,8R)-8-fluoro-2-azabicyclo[5.1.0]octane chemical structure, C7H12FN, CAS 3079346-37-2
Rel-(1R,7S,8R)-8-fluoro-2-azabicyclo[5.1.0]octane
CAS 3079346-37-2C7H12FN