CompoundList
Sign in
Murcko scaffold

Ring system with 3 rings and 17 atoms

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
5
With full pages
1
Scaffold SMILES

O=C1C=C(c2ccc3ccccc3c2)CCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1C=C(c2ccc3ccccc3c2)CCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

RefChem:357155 chemical structure, C17H16O2, CAS 5446-71-9
RefChem:357155
CAS 5446-71-9C17H16O2
3-(Naphthalen-2-yl)-2-[(propan-2-yl)amino]cyclohex-2-en-1-one chemical structure, C19H21NO, CAS 62297-28-3
3-(Naphthalen-2-yl)-2-[(propan-2-yl)amino]cyclohex-2-en-1-one
CAS 62297-28-3C19H21NO
N-(4-(Naphthalen-2-yl)-2-oxocyclohex-3-en-1-yl)acetamide chemical structure, C18H17NO2, CAS 88141-46-2
N-(4-(Naphthalen-2-yl)-2-oxocyclohex-3-en-1-yl)acetamide
CAS 88141-46-2C18H17NO2
2-(Ethylamino)-3-(naphthalen-2-yl)cyclohex-2-en-1-one chemical structure, C18H19NO, CAS 62297-30-7
2-(Ethylamino)-3-(naphthalen-2-yl)cyclohex-2-en-1-one
CAS 62297-30-7C18H19NO
3-(6-(Dimethylamino)naphthalen-2-yl)cyclohex-2-enone chemical structure, C18H19NO, CAS 960319-81-7
3-(6-(Dimethylamino)naphthalen-2-yl)cyclohex-2-enone
CAS 960319-81-7C18H19NO