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Murcko scaffold

Ring system with 4 rings and 27 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
13
With full pages
2
Scaffold SMILES

O=c1[nH]c2ccccc2nc1-c1ccccc1NS(=O)(=O)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c2ccccc2nc1-c1ccccc1NS(=O)(=O)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

4-Methyl-N-(2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide chemical structure, C21H17N3O3S, CAS 316361-54-3
4-Methyl-N-(2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide
CAS 316361-54-3C21H17N3O3S
4-Methoxy-N-[2-(3-oxo-3,4-dihydro-quinoxalin-2-yl)-phenyl]-benzenesulfonamide chemical structure, C21H17N3O4S, CAS 871307-62-9
4-Methoxy-N-[2-(3-oxo-3,4-dihydro-quinoxalin-2-yl)-phenyl]-benzenesulfonamide
CAS 871307-62-9C21H17N3O4S
4-Fluoro-N-[4-methyl-2-(3-oxo-4H-quinoxalin-2-yl)phenyl]benzenesulfonamide chemical structure, C21H16FN3O3S, CAS 899350-93-7
4-Fluoro-N-[4-methyl-2-(3-oxo-4H-quinoxalin-2-yl)phenyl]benzenesulfonamide
CAS 899350-93-7C21H16FN3O3S
N-[4-Chloro-2-(3-oxo-4H-quinoxalin-2-yl)phenyl]benzenesulfonamide chemical structure, C20H14ClN3O3S, CAS 899982-55-9
N-[4-Chloro-2-(3-oxo-4H-quinoxalin-2-yl)phenyl]benzenesulfonamide
CAS 899982-55-9C20H14ClN3O3S
2,4,6-Trimethyl-N-(2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide chemical structure, C23H21N3O3S, CAS 927556-21-6
2,4,6-Trimethyl-N-(2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide
CAS 927556-21-6C23H21N3O3S
N-[4-Methyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-4-nitrobenzene-1-sulfonamide chemical structure, C21H16N4O5S, CAS 927542-74-3
N-[4-Methyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]-4-nitrobenzene-1-sulfonamide
CAS 927542-74-3C21H16N4O5S
2,4,6-Trimethyl-N-(4-methyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide chemical structure, C24H23N3O3S, CAS 927625-44-3
2,4,6-Trimethyl-N-(4-methyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide
CAS 927625-44-3C24H23N3O3S
4-Chloro-N-(4-methyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide chemical structure, C21H16ClN3O3S, CAS 887197-36-6
4-Chloro-N-(4-methyl-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)benzenesulfonamide
CAS 887197-36-6C21H16ClN3O3S
N-(4-Chloro-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)-4-methylbenzenesulfonamide chemical structure, C21H16ClN3O3S, CAS 887197-88-8
N-(4-Chloro-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl)-4-methylbenzenesulfonamide
CAS 887197-88-8C21H16ClN3O3S
N-[4-Bromo-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]benzenesulfonamide chemical structure, C20H14BrN3O3S, CAS 887869-74-1
N-[4-Bromo-2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]benzenesulfonamide
CAS 887869-74-1C20H14BrN3O3S
N-[4-Bromo-2-(3-hydroxyquinoxalin-2-yl)phenyl]-4-methylbenzene-1-sulfonamide chemical structure, C21H16BrN3O3S, CAS 899350-92-6
N-[4-Bromo-2-(3-hydroxyquinoxalin-2-yl)phenyl]-4-methylbenzene-1-sulfonamide
CAS 899350-92-6C21H16BrN3O3S
4-Fluoro-N-(2-(3-hydroxyquinoxalin-2-yl)-6-methylphenyl)benzenesulfonamide chemical structure, C21H16FN3O3S, CAS 1797257-64-7
4-Fluoro-N-(2-(3-hydroxyquinoxalin-2-yl)-6-methylphenyl)benzenesulfonamide
CAS 1797257-64-7C21H16FN3O3S
3-Fluoro-N-[2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]benzene-1-sulfonamide chemical structure, C20H14FN3O3S, CAS 1795345-47-9
3-Fluoro-N-[2-(3-oxo-3,4-dihydroquinoxalin-2-yl)phenyl]benzene-1-sulfonamide
CAS 1795345-47-9C20H14FN3O3S