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Murcko scaffold

Ring system with 5 rings and 20 atoms

5 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
20
Chemicals
5
With full pages
1
Scaffold SMILES

O=C(NC1CCNCC1)NC12CC3CC(CC(C3)C1)C2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(NC1CCNCC1)NC12CC3CC(CC(C3)C1)C2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

1-(1-Adamantyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)urea chemical structure, C20H35N3O, CAS 523991-33-5
1-(1-Adamantyl)-3-(2,2,6,6-tetramethylpiperidin-4-yl)urea
CAS 523991-33-5C20H35N3O
AR-9281 chemical structure, C18H29N3O2, CAS 913548-29-5
AR-9281
CAS 913548-29-5C18H29N3O2
1-(Adamantan-1-yl)-3-(1-propylpiperidin-4-yl)urea chemical structure, C19H33N3O, CAS 897522-46-2
1-(Adamantan-1-yl)-3-(1-propylpiperidin-4-yl)urea
CAS 897522-46-2C19H33N3O
1-(1-Adamantyl)-3-(1-methylsulfonylpiperidin-4-yl)urea chemical structure, C17H29N3O3S, CAS 950184-13-1
1-(1-Adamantyl)-3-(1-methylsulfonylpiperidin-4-yl)urea
CAS 950184-13-1C17H29N3O3S
tert-Butyl 4-(3-(adamantan-1-yl)ureido)piperidine-1-carboxylate chemical structure, C21H35N3O3, CAS 1332699-85-0
tert-Butyl 4-(3-(adamantan-1-yl)ureido)piperidine-1-carboxylate
CAS 1332699-85-0C21H35N3O3