Murcko scaffold
Ring system with 5 rings and 32 atoms
6 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 32
- Chemicals
- 6
- With full pages
- 2
Scaffold SMILES
O=C(Nc1cccc(C(NCC2CC2)c2ccccc2)c1)c1ccnn1-c1ccccc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 6 of 6 chemicals
(+)-1-(3-(Aminomethyl)phenyl)-N-(5-((3-cyanophenyl)(cyclopropyl-methylamino)methyl)-2-fluorophenyl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
CAS 1809010-16-9C30H26F4N6O
Berotralstat
CAS 1809010-50-1C30H26F4N6O
Berotralstat hydrochloride
CAS 1809010-52-3C30H28Cl2F4N6O
MK95Wxp6MU
CAS 2602377-16-0C35H34F4N6O3
(S)-Berotralstat
CAS 1809010-51-2C30H26F4N6O
Berotralstat dihydrochloride, (S)-
CAS 1809010-53-4C30H28Cl2F4N6O