Free for buyers, contact details stay privateFree for buyers. Your contact details stay private until you accept a quote.

Sign in Join free

Murcko scaffold

Ring system with 4 rings and 30 atoms

10 chemicals on CompoundList share this ring system.

Rings: 4
Scaffold atoms: 30
Chemicals: 10
With full pages: 2

Scaffold SMILES

O=C(CCCN1CCC(C(c2ccccc2)c2ccccc2)CC1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold O=C(CCCN1CCC(C(c2ccccc2)c2ccccc2)CC1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

1-Butanone, 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-, hydrochloride (1:1) chemical structure, C32H40ClNO2, CAS 43076-44-4

1-Butanone, 1-(4-(1,1-dimethylethyl)phenyl)-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-, hydrochloride (1:1)

CAS 43076-44-4C₃₂H₄₀ClNO₂

4'-tert-Butyl-4-(4-(hydroxybenzhydryl)piperidino)butyrophenone chemical structure, C32H39NO2, CAS 43076-30-8

4'-tert-Butyl-4-(4-(hydroxybenzhydryl)piperidino)butyrophenone

CAS 43076-30-8C₃₂H₃₉NO₂

Butyrophenone, 4-(4-(p-chloro-alpha-hydroxy-alpha-phenylbenzyl)piperidino)-4'-fluoro-, hydrochloride chemical structure, C28H30Cl2FNO2, CAS 57257-41-7

Butyrophenone, 4-(4-(p-chloro-alpha-hydroxy-alpha-phenylbenzyl)piperidino)-4'-fluoro-, hydrochloride

CAS 57257-41-7C₂₈H₃₀Cl₂FNO₂

1-Butanone, 1-(4-fluorophenyl)-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-, hydrochloride chemical structure, C28H31ClFNO2, CAS 43076-39-7

1-Butanone, 1-(4-fluorophenyl)-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)-, hydrochloride

CAS 43076-39-7C₂₈H₃₁ClFNO₂

2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid chemical structure, C32H37NO4, CAS 76811-98-8

2-(4-(4-(4-(Hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoic acid

CAS 76811-98-8C₃₂H₃₇NO₄

2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid methyl ester chemical structure, C33H39NO4, CAS 154477-55-1

2-[4-[4-[4-(Hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]phenyl]-2,2-dimethylacetic acid methyl ester

CAS 154477-55-1C₃₃H₃₉NO₄

Ethyl 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethylbenzeneacetate chemical structure, C34H41NO4, CAS 76812-02-7

Ethyl 4-[4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl]-alpha,alpha-dimethylbenzeneacetate

CAS 76812-02-7C₃₄H₄₁NO₄

Ethyl 4-{4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl}-alpha,alpha-dimethylbenzeneacetate hydrochloride chemical structure, C34H42ClNO4, CAS 76811-96-6

Ethyl 4-{4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-oxobutyl}-alpha,alpha-dimethylbenzeneacetate hydrochloride

CAS 76811-96-6C₃₄H₄₂ClNO₄

Methyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate hydrochloride chemical structure, C33H40ClNO4, CAS 169280-33-5

Methyl 2-(4-(4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butanoyl)phenyl)-2-methylpropanoate hydrochloride

CAS 169280-33-5C₃₃H₄₀ClNO₄

1-Keto descarboxy 1-deshydroxy fexofenadine chemical structure, C31H37NO2, CAS 185066-40-4

1-Keto descarboxy 1-deshydroxy fexofenadine

CAS 185066-40-4C₃₁H₃₇NO₂