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Murcko scaffold

2-(2-Oxo-2-piperidin-1-ylethyl)sulfanyl-3-phenyl-5H-pyrimido[5,4-b]indol-4-one scaffold

26 chemicals on CompoundList share this ring system.

Rings: 5
Scaffold atoms: 30
Chemicals: 26
With full pages: 5

Scaffold SMILES

O=C(CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1)N1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 2-(2-Oxo-2-piperidin-1-ylethyl)sulfanyl-3-phenyl-5H-pyrimido[5,4-b]indol-4-one page

Murcko scaffold O=C(CSc1nc2c([nH]c3ccccc32)c(=O)n1-c1ccccc1)N1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 26 of 26 chemicals

2-(2-Oxo-2-piperidin-1-ylethyl)sulfanyl-3-phenyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C23H22N4O2S, CAS 537668-61-4

2-(2-Oxo-2-piperidin-1-ylethyl)sulfanyl-3-phenyl-5H-pyrimido[5,4-b]indol-4-one

CAS 537668-61-4C₂₃H₂₂N₄O₂S

3-(4-Methylphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C24H24N4O2S, CAS 536704-36-6

3-(4-Methylphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536704-36-6C₂₄H₂₄N₄O₂S

3-(4-Methylphenyl)-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C25H26N4O2S, CAS 536704-39-9

3-(4-Methylphenyl)-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536704-39-9C₂₅H₂₆N₄O₂S

3-(3,5-Dimethylphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C25H26N4O2S, CAS 536705-31-4

3-(3,5-Dimethylphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536705-31-4C₂₅H₂₆N₄O₂S

3-(3,5-Dimethylphenyl)-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C26H28N4O2S, CAS 536705-34-7

3-(3,5-Dimethylphenyl)-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536705-34-7C₂₆H₂₈N₄O₂S

3-(3-Methoxyphenyl)-2-((2-oxo-2-(piperidin-1-yl)ethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C24H24N4O3S, CAS 536706-25-9

3-(3-Methoxyphenyl)-2-((2-oxo-2-(piperidin-1-yl)ethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536706-25-9C₂₄H₂₄N₄O₃S

3-(4-Methoxyphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C24H24N4O3S, CAS 536707-19-4

3-(4-Methoxyphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536707-19-4C₂₄H₂₄N₄O₃S

3-(4-Ethoxyphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C25H26N4O3S, CAS 536708-13-1

3-(4-Ethoxyphenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536708-13-1C₂₅H₂₆N₄O₃S

3-(4-Ethoxyphenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C26H28N4O3S, CAS 536708-16-4

3-(4-Ethoxyphenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536708-16-4C₂₆H₂₈N₄O₃S

3-(4-Fluorophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C23H21FN4O2S, CAS 536710-64-2

3-(4-Fluorophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536710-64-2C₂₃H₂₁FN₄O₂S

3-(3-Chlorophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C23H21ClN4O2S, CAS 536712-43-3

3-(3-Chlorophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536712-43-3C₂₃H₂₁ClN₄O₂S

3-(4-Chlorophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C23H21ClN4O2S, CAS 536714-30-4

3-(4-Chlorophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536714-30-4C₂₃H₂₁ClN₄O₂S

2-(2-Oxo-2-piperidin-1-ylethyl)sulfanyl-3-[3-(trifluoromethyl)phenyl]-5H-pyrimido[5,4-b]indol-4-one chemical structure, C24H21F3N4O2S, CAS 536715-65-8

2-(2-Oxo-2-piperidin-1-ylethyl)sulfanyl-3-[3-(trifluoromethyl)phenyl]-5H-pyrimido[5,4-b]indol-4-one

CAS 536715-65-8C₂₄H₂₁F₃N₄O₂S

3-(4-Nitrophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C23H21N5O4S, CAS 536716-63-9

3-(4-Nitrophenyl)-2-(2-oxo-2-piperidin-1-ylethyl)sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536716-63-9C₂₃H₂₁N₅O₄S

2-[2-(2-Ethylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3-phenyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C25H26N4O2S, CAS 537668-65-8

2-[2-(2-Ethylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3-phenyl-5H-pyrimido[5,4-b]indol-4-one

CAS 537668-65-8C₂₅H₂₆N₄O₂S

3-(4-Methoxyphenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C25H26N4O3S, CAS 536707-22-9

3-(4-Methoxyphenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536707-22-9C₂₅H₂₆N₄O₃S

3-(4-Chlorophenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C24H23ClN4O2S, CAS 536714-36-0

3-(4-Chlorophenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536714-36-0C₂₄H₂₃ClN₄O₂S

3-(4-Fluorophenyl)-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5H-pyrimido[5,4-b]indol-4-one chemical structure, C24H23FN4O2S, CAS 536710-69-7

3-(4-Fluorophenyl)-2-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]sulfanyl-5H-pyrimido[5,4-b]indol-4-one

CAS 536710-69-7C₂₄H₂₃FN₄O₂S

2-((2-(2-Ethylpiperidin-1-yl)-2-oxoethyl)thio)-3-(4-methoxyphenyl)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C26H28N4O3S, CAS 536707-23-0

2-((2-(2-Ethylpiperidin-1-yl)-2-oxoethyl)thio)-3-(4-methoxyphenyl)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536707-23-0C₂₆H₂₈N₄O₃S

3-(3-Methoxyphenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C25H26N4O3S, CAS 536706-28-2

3-(3-Methoxyphenyl)-2-((2-(4-methylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536706-28-2C₂₅H₂₆N₄O₃S

2-[2-(2-Ethylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3-(4-fluorophenyl)-5H-pyrimido[5,4-b]indol-4-one chemical structure, C25H25FN4O2S, CAS 536710-70-0

2-[2-(2-Ethylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3-(4-fluorophenyl)-5H-pyrimido[5,4-b]indol-4-one

CAS 536710-70-0C₂₅H₂₅FN₄O₂S

3-(4-Ethoxyphenyl)-2-((2-(2-ethylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C27H30N4O3S, CAS 536708-17-5

3-(4-Ethoxyphenyl)-2-((2-(2-ethylpiperidin-1-yl)-2-oxoethyl)thio)-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 536708-17-5C₂₇H₃₀N₄O₃S

2-[2-(2-Ethylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3-(3-methoxyphenyl)-5H-pyrimido[5,4-b]indol-4-one chemical structure, C26H28N4O3S, CAS 536706-29-3

2-[2-(2-Ethylpiperidin-1-yl)-2-oxoethyl]sulfanyl-3-(3-methoxyphenyl)-5H-pyrimido[5,4-b]indol-4-one

CAS 536706-29-3C₂₆H₂₈N₄O₃S

2-((2-(4-Methylpiperidin-1-yl)-2-oxoethyl)thio)-3-phenyl-3H-pyrimido[5,4-b]indol-4(5H)-one chemical structure, C24H24N4O2S, CAS 537668-64-7

2-((2-(4-Methylpiperidin-1-yl)-2-oxoethyl)thio)-3-phenyl-3H-pyrimido[5,4-b]indol-4(5H)-one

CAS 537668-64-7C₂₄H₂₄N₄O₂S