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Murcko scaffold

Ring system with 3 rings and 15 atoms

6 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
6
With full pages
1
Scaffold SMILES

O=c1ncnc2[nH]c3ccccc3cc1-2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1ncnc2[nH]c3ccccc3cc1-2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

2-Amino-10-ethylpyrimido[4,5-b]quinolin-4(10H)-one chemical structure, C13H12N4O, CAS 137932-41-3
2-Amino-10-ethylpyrimido[4,5-b]quinolin-4(10H)-one
CAS 137932-41-3C13H12N4O
10-Methyl-2-methylthio-pyrimido[4,5-b]1,2-dihydroquinolin-4(1H)-one chemical structure, C13H11N3OS, CAS 948578-68-5
10-Methyl-2-methylthio-pyrimido[4,5-b]1,2-dihydroquinolin-4(1H)-one
CAS 948578-68-5C13H11N3OS
Pirolate chemical structure, C16H15N3O5, CAS 55149-05-8
Pirolate
CAS 55149-05-8C16H15N3O5
Ethyl 7-methoxy-8-ethoxypyrimido[4,5-b]quinoline-4(3H)-one-2-carboxylate chemical structure, C17H17N3O5, CAS 55149-37-6
Ethyl 7-methoxy-8-ethoxypyrimido[4,5-b]quinoline-4(3H)-one-2-carboxylate
CAS 55149-37-6C17H17N3O5
Ethyl 3,4-dihydro-4-oxopyrimido(4,5-b)quinoline-2-carboxylate chemical structure, C14H11N3O3, CAS 55149-04-7
Ethyl 3,4-dihydro-4-oxopyrimido(4,5-b)quinoline-2-carboxylate
CAS 55149-04-7C14H11N3O3
Butyl 3,4-dihydro-7,8-dimethoxy-4-oxopyrimido[4,5-b]quinoline-2-carboxylate chemical structure, C18H19N3O5, CAS 55149-06-9
Butyl 3,4-dihydro-7,8-dimethoxy-4-oxopyrimido[4,5-b]quinoline-2-carboxylate
CAS 55149-06-9C18H19N3O5