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Murcko scaffold

8,13,13b,14-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one scaffold

12 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
22
Chemicals
12
With full pages
4
Scaffold SMILES

O=C1c2ccccc2NC2c3[nH]c4ccccc4c3CCN12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 8,13,13b,14-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one page
Murcko scaffold O=C1c2ccccc2NC2c3[nH]c4ccccc4c3CCN12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

Isoevodiamine chemical structure, C19H17N3O, CAS 5956-87-6
Isoevodiamine
CAS 5956-87-6C19H17N3O
Evodiamine chemical structure, C19H17N3O, CAS 518-17-2
Evodiamine
CAS 518-17-2C19H17N3O
8,13,13b,14-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one chemical structure, C18H15N3O, CAS 59863-00-2
8,13,13b,14-Tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
CAS 59863-00-2C18H15N3O
7-Fluoro-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15,17,19-heptaen-14-one chemical structure, C19H16FN3O, CAS 706789-63-1
7-Fluoro-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15,17,19-heptaen-14-one
CAS 706789-63-1C19H16FN3O
Hydroxy evodiamine chemical structure, C19H17N3O2, CAS 1238-43-3
Hydroxy evodiamine
CAS 1238-43-3C19H17N3O2
(1S)-7-Hydroxy-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15,17,19-heptaen-14-one chemical structure, C19H17N3O2, CAS 920265-63-0
(1S)-7-Hydroxy-21-methyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15,17,19-heptaen-14-one
CAS 920265-63-0C19H17N3O2
(R)-3-Fluoro-10-hydroxy-14-methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one chemical structure, C19H16FN3O2, CAS 1355078-09-9
(R)-3-Fluoro-10-hydroxy-14-methyl-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(13H)-one
CAS 1355078-09-9C19H16FN3O2
3-(14-Methyl-5-oxo-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-13(5H)-yl)propanoic acid chemical structure, C22H21N3O3, CAS 1987341-48-9
3-(14-Methyl-5-oxo-7,8,13b,14-tetrahydroindolo[2',3':3,4]pyrido[2,1-b]quinazolin-13(5H)-yl)propanoic acid
CAS 1987341-48-9C22H21N3O3
Tubulin inhibitor 35 chemical structure, C21H21N3O, CAS 2247047-77-2
Tubulin inhibitor 35
CAS 2247047-77-2C21H21N3O
3-Amino-8,13,13b,14-tetrahydroindolo[2 inverted exclamation marka,3 inverted exclamation marka:3,4]pyrido[2,1-b]quinazolin-5(7H)-one chemical structure, C18H16N4O, CAS 2377675-25-5
3-Amino-8,13,13b,14-tetrahydroindolo[2 inverted exclamation marka,3 inverted exclamation marka:3,4]pyrido[2,1-b]quinazolin-5(7H)-one
CAS 2377675-25-5C18H16N4O
(21-Methyl-14-oxo-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15,17,19-heptaen-7-yl) acetate chemical structure, C21H19N3O3, CAS 2820245-53-0
(21-Methyl-14-oxo-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4(9),5,7,15,17,19-heptaen-7-yl) acetate
CAS 2820245-53-0C21H19N3O3
21-Prop-2-enyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one chemical structure, C21H19N3O, CAS 2247047-81-8
21-Prop-2-enyl-3,13,21-triazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15,17,19-heptaen-14-one
CAS 2247047-81-8C21H19N3O