CompoundList
Sign in
Murcko scaffold

Ring system with 5 rings and 32 atoms

10 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
10
With full pages
6
Scaffold SMILES

O=S(=O)(c1cccc(-c2nnc(Nc3ccccc3)c3ccccc23)c1)N1CCOCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1cccc(-c2nnc(Nc3ccccc3)c3ccccc23)c1)N1CCOCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

N-(4-Fluorophenyl)-4-(4-methyl-3-morpholin-4-ylsulfonylphenyl)phthalazin-1-amine chemical structure, C25H23FN4O3S, CAS 442648-95-5
N-(4-Fluorophenyl)-4-(4-methyl-3-morpholin-4-ylsulfonylphenyl)phthalazin-1-amine
CAS 442648-95-5C25H23FN4O3S
4-[4-Methyl-3-(morpholin-4-ylsulfonyl)phenyl]-N-phenylphthalazin-1-amine chemical structure, C25H24N4O3S, CAS 330829-51-1
4-[4-Methyl-3-(morpholin-4-ylsulfonyl)phenyl]-N-phenylphthalazin-1-amine
CAS 330829-51-1C25H24N4O3S
N-(2,4-Dimethylphenyl)-4-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl]phthalazin-1-amine chemical structure, C27H28N4O3S, CAS 374917-65-4
N-(2,4-Dimethylphenyl)-4-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl]phthalazin-1-amine
CAS 374917-65-4C27H28N4O3S
N-(4-Chlorophenyl)-4-(4-methyl-3-morpholin-4-ylsulfonylphenyl)phthalazin-1-amine chemical structure, C25H23ClN4O3S, CAS 364383-70-0
N-(4-Chlorophenyl)-4-(4-methyl-3-morpholin-4-ylsulfonylphenyl)phthalazin-1-amine
CAS 364383-70-0C25H23ClN4O3S
4-((4-(4-Methyl-3-(morpholinosulfonyl)phenyl)phthalazin-1-yl)amino)phenol chemical structure, C25H24N4O4S, CAS 376374-54-8
4-((4-(4-Methyl-3-(morpholinosulfonyl)phenyl)phthalazin-1-yl)amino)phenol
CAS 376374-54-8C25H24N4O4S
N-(3,4-Dichlorophenyl)-4-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl]phthalazin-1-amine chemical structure, C25H22Cl2N4O3S, CAS 375362-54-2
N-(3,4-Dichlorophenyl)-4-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl]phthalazin-1-amine
CAS 375362-54-2C25H22Cl2N4O3S
4-(4-Methyl-3-morpholin-4-ylsulfonylphenyl)-N-(4-methylphenyl)phthalazin-1-amine chemical structure, C26H26N4O3S, CAS 375364-22-0
4-(4-Methyl-3-morpholin-4-ylsulfonylphenyl)-N-(4-methylphenyl)phthalazin-1-amine
CAS 375364-22-0C26H26N4O3S
N-Methyl-4-({4-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl]phthalazin-1-yl}amino)benzamide chemical structure, C27H27N5O4S, CAS 375835-06-6
N-Methyl-4-({4-[4-methyl-3-(morpholin-4-ylsulfonyl)phenyl]phthalazin-1-yl}amino)benzamide
CAS 375835-06-6C27H27N5O4S
N-(4-Methoxyphenyl)-4-(4-methyl-3-morpholin-4-ylsulfonylphenyl)phthalazin-1-amine chemical structure, C26H26N4O4S, CAS 364596-66-7
N-(4-Methoxyphenyl)-4-(4-methyl-3-morpholin-4-ylsulfonylphenyl)phthalazin-1-amine
CAS 364596-66-7C26H26N4O4S
4-[4-Methyl-3-(morpholin-4-ylsulfonyl)phenyl]-N-[3-(trifluoromethyl)phenyl]phthalazin-1-amine chemical structure, C26H23F3N4O3S, CAS 442648-99-9
4-[4-Methyl-3-(morpholin-4-ylsulfonyl)phenyl]-N-[3-(trifluoromethyl)phenyl]phthalazin-1-amine
CAS 442648-99-9C26H23F3N4O3S