Murcko scaffold
Ring system with 5 rings and 25 atoms
16 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 25
- Chemicals
- 16
- With full pages
- 1
Scaffold SMILES
O=C(OCC1c2ccccc2-c2ccccc21)N1Cc2c[nH]nc2C1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1Cc2c[nH]nc2C1](/scaffold/PVNUUSZAJHPWPQ-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 16 of 16 chemicals
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C22H19N3O4, CAS 2137503-37-6](/s/PITUBEJPZIVPLI-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137503-37-6C22H19N3O4
5-(((9H-Fluoren-9-yl)methoxy)carbonyl)-6,6-dimethyl-1H,4H,5H,6H-pyrrolo(3,4-c)pyrazole-3-carboxylic acid
CAS 2247103-13-3C23H21N3O4
![5-(9H-Fluoren-9-ylmethoxycarbonyl)-1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C22H19N3O4, CAS 2309445-74-5](/s/ZWEMTYCPJUZSOS-UHFFFAOYSA-N.svg)
5-(9H-Fluoren-9-ylmethoxycarbonyl)-1-methyl-4,6-dihydropyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2309445-74-5C22H19N3O4
![2-Butyl-5-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C25H25N3O4, CAS 2137472-66-1](/s/YMJLGLDOIWTJAK-UHFFFAOYSA-N.svg)
2-Butyl-5-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137472-66-1C25H25N3O4
![2-tert-Butyl-5-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C25H25N3O4, CAS 2137506-83-1](/s/CTBKGHXPQFBLBS-UHFFFAOYSA-N.svg)
2-tert-Butyl-5-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137506-83-1C25H25N3O4
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(propan-2-yl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C24H23N3O4, CAS 2137476-63-0](/s/RFOLMRTYNLFGOA-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(propan-2-yl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137476-63-0C24H23N3O4
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-propyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C24H23N3O4, CAS 2137509-19-2](/s/DLNBZQRHEOCSCS-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-propyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137509-19-2C24H23N3O4
![2-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl)acetic acid chemical structure, C22H19N3O4, CAS 2172258-81-8](/s/XFMSESXLYASVDB-UHFFFAOYSA-N.svg)
2-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-4-yl)acetic acid
CAS 2172258-81-8C22H19N3O4
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C21H17N3O4, CAS 2171598-26-6](/s/GZCHWLQREUNLMM-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2171598-26-6C21H17N3O4
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C22H19N3O4, CAS 2803846-84-4](/s/IXTZFPXWFVGMJD-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1-methyl-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2803846-84-4C22H19N3O4
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C21H17N3O4, CAS 2751610-72-5](/s/APEKRBFYLOPPIG-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2751610-72-5C21H17N3O4
![2-Ethyl-5-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C23H21N3O4, CAS 2137503-35-4](/s/MHABYYHVXUHOBE-UHFFFAOYSA-N.svg)
2-Ethyl-5-{[(9H-fluoren-9-yl)methoxy]carbonyl}-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137503-35-4C23H21N3O4
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(2,2,2-trifluoroethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid chemical structure, C23H18F3N3O4, CAS 2137470-27-8](/s/ZMJOZYANLXDIGX-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-(2,2,2-trifluoroethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-4-carboxylic acid
CAS 2137470-27-8C23H18F3N3O4
![(9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate chemical structure, C21H19N3O3, CAS 2764001-71-8](/s/BTIDCFYIJGHISH-UHFFFAOYSA-N.svg)
(9H-Fluoren-9-yl)methyl 4-(hydroxymethyl)-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-5-carboxylate
CAS 2764001-71-8C21H19N3O3
![5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid chemical structure, C22H19N3O4, CAS 2913407-13-1](/s/BBAJBNPGXOPWIP-UHFFFAOYSA-N.svg)
5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-2-methyl-2H,4H,5H,6H-pyrrolo[3,4-c]pyrazole-3-carboxylic acid
CAS 2913407-13-1C22H19N3O4
![2-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-1-yl)acetic acid chemical structure, C22H19N3O4, CAS 3026712-37-5](/s/FLXMTNNUKLRSIV-UHFFFAOYSA-N.svg)
2-(5-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-1-yl)acetic acid
CAS 3026712-37-5C22H19N3O4
Related scaffolds
Same ring framework with different atoms or bond orders
